cloperastine-3408 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the cloperastine-3408 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C11ORF16 chromosome 11 open reading frame 16
C14ORF79 chromosome 14 open reading frame 79
C1ORF105 chromosome 1 open reading frame 105
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAPN15 calpain 15
CCNG2 cyclin G2
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CNTNAP2 contactin associated protein-like 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DICER1 dicer 1, ribonuclease type III
DLX2 distal-less homeobox 2
EGR1 early growth response 1
EIF1 eukaryotic translation initiation factor 1
ERCC5 excision repair cross-complementation group 5
FAM46C family with sequence similarity 46, member C
FAS Fas cell surface death receptor
FGL1 fibrinogen-like 1
FKBP8 FK506 binding protein 8, 38kDa
GM2A GM2 ganglioside activator
GOLGB1 golgin B1
GPR87 G protein-coupled receptor 87
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPG2 heparan sulfate proteoglycan 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
IQCE IQ motif containing E
IRS2 insulin receptor substrate 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KHSRP KH-type splicing regulatory protein
KLHL24 kelch-like family member 24
KLHL28 kelch-like family member 28
LEPR leptin receptor
LMAN1 lectin, mannose-binding, 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MPZL1 myelin protein zero-like 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MTCL1 microtubule crosslinking factor 1
MYL10 myosin, light chain 10, regulatory
NEB nebulin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NKX3-2 NK3 homeobox 2
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCDHA6 protocadherin alpha 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POPDC3 popeye domain containing 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
RND1 Rho family GTPase 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RTN2 reticulon 2
S100A13 S100 calcium binding protein A13
SAMD4A sterile alpha motif domain containing 4A
SCAMP4 secretory carrier membrane protein 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SPRED2 sprouty-related, EVH1 domain containing 2
SRCAP Snf2-related CREBBP activator protein
SRPX sushi-repeat containing protein, X-linked
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D17 TBC1 domain family, member 17
TBCD tubulin folding cofactor D
TBX19 T-box 19
TNK2 tyrosine kinase, non-receptor, 2
TOP3A topoisomerase (DNA) III alpha
TREX1 three prime repair exonuclease 1
TRIB3 tribbles pseudokinase 3
TUBGCP3 tubulin, gamma complex associated protein 3
UBA7 ubiquitin-like modifier activating enzyme 7
VASH1 vasohibin 1
VEGFA vascular endothelial growth factor A
WDR62 WD repeat domain 62
ZFP64 ZFP64 zinc finger protein
ZNF287 zinc finger protein 287
ZNF639 zinc finger protein 639
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C17ORF80 chromosome 17 open reading frame 80
C19ORF24 chromosome 19 open reading frame 24
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC25 coiled-coil domain containing 25
CFAP44 cilia and flagella associated protein 44
CGREF1 cell growth regulator with EF-hand domain 1
CHML choroideremia-like (Rab escort protein 2)
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF16 DDB1 and CUL4 associated factor 16
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELMO3 engulfment and cell motility 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
ERCC4 excision repair cross-complementation group 4
EVPL envoplakin
FAR2 fatty acyl CoA reductase 2
FBXO22 F-box protein 22
FKBPL FK506 binding protein like
FMO4 flavin containing monooxygenase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLCE glucuronic acid epimerase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA0125 KIAA0125
KIAA0895 KIAA0895
LAMB2 laminin, beta 2 (laminin S)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00115 long intergenic non-protein coding RNA 115
LOC730101 uncharacterized LOC730101
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MATK megakaryocyte-associated tyrosine kinase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED15 mediator complex subunit 15
METTL2B methyltransferase like 2B
MON1B MON1 secretory trafficking family member B
MRPL11 mitochondrial ribosomal protein L11
MVD mevalonate (diphospho) decarboxylase
NDRG4 NDRG family member 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRGN neurogranin (protein kinase C substrate, RC3)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP12 poly (ADP-ribose) polymerase family, member 12
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZRN3 PDZ domain containing ring finger 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PNPO pyridoxamine 5'-phosphate oxidase
PODXL2 podocalyxin-like 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRPH peripherin
PTK6 protein tyrosine kinase 6
RCOR3 REST corepressor 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFWD3 ring finger and WD repeat domain 3
RIBC2 RIB43A domain with coiled-coils 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPS17P5 ribosomal protein S17 pseudogene 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNHG3 small nucleolar RNA host gene 3
SRD5A3 steroid 5 alpha-reductase 3
STAG3 stromal antigen 3
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TNS2 tensin 2
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSPAN15 tetraspanin 15
TTC30A tetratricopeptide repeat domain 30A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VASP vasodilator-stimulated phosphoprotein
VAX2 ventral anterior homeobox 2
VEGFC vascular endothelial growth factor C
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZC3H3 zinc finger CCCH-type containing 3
ZNF574 zinc finger protein 574
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862