clofilium tosylate-4492 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the clofilium tosylate-4492 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKH ANKH inorganic pyrophosphate transport regulator
ANP32A-IT1 ANP32A intronic transcript 1
APAF1 apoptotic peptidase activating factor 1
ARHGAP26 Rho GTPase activating protein 26
ARL3 ADP-ribosylation factor-like 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF7IP activating transcription factor 7 interacting protein
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B9D1 B9 protein domain 1
BCAS1 breast carcinoma amplified sequence 1
C4ORF29 chromosome 4 open reading frame 29
CCDC170 coiled-coil domain containing 170
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLTCL1 clathrin, heavy chain-like 1
COL9A3 collagen, type IX, alpha 3
CSF1 colony stimulating factor 1 (macrophage)
CUZD1 CUB and zona pellucida-like domains 1
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT4 DNA-damage-inducible transcript 4
DFNB31 deafness, autosomal recessive 31
DPY19L1 dpy-19-like 1 (C. elegans)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EMC3 ER membrane protein complex subunit 3
ERAP1 endoplasmic reticulum aminopeptidase 1
EREG epiregulin
ESR1 estrogen receptor 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM63B family with sequence similarity 63, member B
FRS3 fibroblast growth factor receptor substrate 3
GLB1L galactosidase, beta 1-like
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR1 G protein-coupled receptor 1
HPX hemopexin
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
LAMC3 laminin, gamma 3
LAPTM5 lysosomal protein transmembrane 5
LINC00472 long intergenic non-protein coding RNA 472
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MFAP3 microfibrillar-associated protein 3
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPZ myelin protein zero
MYO1B myosin IB
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCAPH2 non-SMC condensin II complex, subunit H2
NCOR2 nuclear receptor corepressor 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NGLY1 N-glycanase 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRF1 nuclear respiratory factor 1
OLFML2B olfactomedin-like 2B
PDE4A phosphodiesterase 4A, cAMP-specific
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRDM1 PR domain containing 1, with ZNF domain
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTBP3 polypyrimidine tract binding protein 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PTPRU protein tyrosine phosphatase, receptor type, U
QKI QKI, KH domain containing, RNA binding
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3D RAB3D, member RAS oncogene family
RANBP1 RAN binding protein 1
RND1 Rho family GTPase 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SENP5 SUMO1/sentrin specific peptidase 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
STOML1 stomatin (EPB72)-like 1
STRN3 striatin, calmodulin binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TRIO trio Rho guanine nucleotide exchange factor
TRO trophinin
TTC38 tetratricopeptide repeat domain 38
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WSB1 WD repeat and SOCS box containing 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF41 zinc finger protein 41
ZNF652 zinc finger protein 652
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRB2 adhesion G protein-coupled receptor B2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARMC6 armadillo repeat containing 6
ARMCX4 armadillo repeat containing, X-linked 4
ATG10 autophagy related 10
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BFSP1 beaded filament structural protein 1, filensin
BTBD18 BTB (POZ) domain containing 18
C14ORF79 chromosome 14 open reading frame 79
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBX8 chromobox homolog 8
CCNE1 cyclin E1
CCRL2 chemokine (C-C motif) receptor-like 2
CDHR2 cadherin-related family member 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
E4F1 E4F transcription factor 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ELMO3 engulfment and cell motility 3
EXOSC1 exosome component 1
FAM46C family with sequence similarity 46, member C
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL1 guanine nucleotide binding protein-like 1
GPR27 G protein-coupled receptor 27
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H3A histone cluster 1, H3a
HIST1H3C histone cluster 1, H3c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA7 homeobox A7
HPN hepsin
HYAL3 hyaluronoglucosaminidase 3
IFNA14 interferon, alpha 14
IQSEC2 IQ motif and Sec7 domain 2
ISYNA1 inositol-3-phosphate synthase 1
KDM5C lysine (K)-specific demethylase 5C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LOC100287590 uncharacterized LOC100287590
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP4 low density lipoprotein receptor-related protein 4
LTC4S leukotriene C4 synthase
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEA5 melanoma antigen family A5
MDFI MyoD family inhibitor
MEGF8 multiple EGF-like-domains 8
MFAP2 microfibrillar-associated protein 2
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
NME5 NME/NM23 family member 5
NNAT neuronatin
NPIPB15 nuclear pore complex interacting protein family, member B15
NTSR1 neurotensin receptor 1 (high affinity)
OSR2 odd-skipped related transciption factor 2
PARD6A par-6 family cell polarity regulator alpha
PCDHA9 protocadherin alpha 9
PID1 phosphotyrosine interaction domain containing 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLXNB3 plexin B3
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRB3 proline-rich protein BstNI subfamily 3
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAA4 serum amyloid A4, constitutive
SLC22A14 solute carrier family 22, member 14
SPEG SPEG complex locus
STAC SH3 and cysteine rich domain
STMN4 stathmin-like 4
SYNPO synaptopodin
TCTN2 tectonic family member 2
TESPA1 thymocyte expressed, positive selection associated 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TUBA4B tubulin, alpha 4b
UNC119 unc-119 homolog (C. elegans)
WT1-AS WT1 antisense RNA
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNF214 zinc finger protein 214
ZNF574 zinc finger protein 574