clobetasol-4497 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the clobetasol-4497 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAP1 ArfGAP with dual PH domains 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANGPTL4 angiopoietin-like 4
ATF7IP activating transcription factor 7 interacting protein
BMP1 bone morphogenetic protein 1
C18ORF25 chromosome 18 open reading frame 25
C1ORF61 chromosome 1 open reading frame 61
CACFD1 calcium channel flower domain containing 1
CCR1 chemokine (C-C motif) receptor 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFAP70 cilia and flagella associated protein 70
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
CLCA1 chloride channel accessory 1
CLEC3B C-type lectin domain family 3, member B
CNTD2 cyclin N-terminal domain containing 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DPF1 D4, zinc and double PHD fingers family 1
DSCAM Down syndrome cell adhesion molecule
DUSP1 dual specificity phosphatase 1
EFNB2 ephrin-B2
EGR1 early growth response 1
ERC2 ELKS/RAB6-interacting/CAST family member 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2 fibroblast growth factor receptor 2
FMO5 flavin containing monooxygenase 5
GAS7 growth arrest-specific 7
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H4B histone cluster 1, H4b
HUS1 HUS1 checkpoint homolog (S. pombe)
IGFALS insulin-like growth factor binding protein, acid labile subunit
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INE1 inactivation escape 1 (non-protein coding)
IQCC IQ motif containing C
ITGB6 integrin, beta 6
JADE2 jade family PHD finger 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0319L KIAA0319-like
KIAA0391 KIAA0391
KIAA1467 KIAA1467
KLK13 kallikrein-related peptidase 13
KRT19P2 keratin 19 pseudogene 2
KRT6A keratin 6A, type II
LBP lipopolysaccharide binding protein
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MBP myelin basic protein
MLNR motilin receptor
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAV2 neuron navigator 2
NEBL nebulette
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NNMT nicotinamide N-methyltransferase
NPHP1 nephronophthisis 1 (juvenile)
NR4A3 nuclear receptor subfamily 4, group A, member 3
PCDH11Y protocadherin 11 Y-linked
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE9A phosphodiesterase 9A
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLAG1 pleiomorphic adenoma gene 1
PRKCE protein kinase C, epsilon
PSG1 pregnancy specific beta-1-glycoprotein 1
PTCRA pre T-cell antigen receptor alpha
RAB36 RAB36, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RLN2 relaxin 2
RUNX1 runt-related transcription factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SPHK2 sphingosine kinase 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STRA6 stimulated by retinoic acid 6
STRN3 striatin, calmodulin binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYN3 synapsin III
TACC1 transforming, acidic coiled-coil containing protein 1
TAOK2 TAO kinase 2
TJP3 tight junction protein 3
TLR2 toll-like receptor 2
TNK2 tyrosine kinase, non-receptor, 2
TSC22D2 TSC22 domain family, member 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AADAC arylacetamide deacetylase
ANXA10 annexin A10
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARL15 ADP-ribosylation factor-like 15
ARMCX4 armadillo repeat containing, X-linked 4
C14ORF93 chromosome 14 open reading frame 93
C4ORF19 chromosome 4 open reading frame 19
CBX8 chromobox homolog 8
CCL27 chemokine (C-C motif) ligand 27
CD101 CD101 molecule
CDKN2AIP CDKN2A interacting protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGREF1 cell growth regulator with EF-hand domain 1
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COBL cordon-bleu WH2 repeat protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DCAF17 DDB1 and CUL4 associated factor 17
DFNB31 deafness, autosomal recessive 31
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOC2A double C2-like domains, alpha
DPF3 D4, zinc and double PHD fingers, family 3
DTX2 deltex 2, E3 ubiquitin ligase
EDC4 enhancer of mRNA decapping 4
EGF epidermal growth factor
ELMO3 engulfment and cell motility 3
FAM204A family with sequence similarity 204, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FKBP10 FK506 binding protein 10, 65 kDa
FZD3 frizzled class receptor 3
FZD8 frizzled class receptor 8
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDAP1 ganglioside induced differentiation associated protein 1
GDAP2 ganglioside induced differentiation associated protein 2
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNL1 guanine nucleotide binding protein-like 1
GRPR gastrin-releasing peptide receptor
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AI histone cluster 1, H2ai
HOXA6 homeobox A6
HYAL3 hyaluronoglucosaminidase 3
IL1B interleukin 1, beta
IL33 interleukin 33
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1462 KIAA1462
KRI1 KRI1 homolog (S. cerevisiae)
KRT75 keratin 75, type II
LIG4 ligase IV, DNA, ATP-dependent
LMO7 LIM domain 7
LY86 lymphocyte antigen 86
MAGEF1 melanoma antigen family F1
MAP1S microtubule-associated protein 1S
MCC mutated in colorectal cancers
MXD3 MAX dimerization protein 3
NBEAL2 neurobeachin-like 2
NME5 NME/NM23 family member 5
NOL6 nucleolar protein 6 (RNA-associated)
NPY1R neuropeptide Y receptor Y1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PAQR6 progestin and adipoQ receptor family member VI
PARM1 prostate androgen-regulated mucin-like protein 1
PAX9 paired box 9
PC pyruvate carboxylase
PCDHA9 protocadherin alpha 9
PDE12 phosphodiesterase 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLAU plasminogen activator, urokinase
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK2 polo-like kinase 2
PODXL2 podocalyxin-like 2
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PROSER1 proline and serine rich 1
PRR7 proline rich 7 (synaptic)
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
S100A3 S100 calcium binding protein A3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SPEG SPEG complex locus
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TUBG2 tubulin, gamma 2
TXLNG taxilin gamma
VN1R1 vomeronasal 1 receptor 1
WNT7A wingless-type MMTV integration site family, member 7A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF675 zinc finger protein 675
ZNF702P zinc finger protein 702, pseudogene
ZNF711 zinc finger protein 711
ZNF76 zinc finger protein 76