clemastine-2412 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the clemastine-2412 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
ADGRB1 adhesion G protein-coupled receptor B1
AGTPBP1 ATP/GTP binding protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ANGEL2 angel homolog 2 (Drosophila)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNT aryl hydrocarbon receptor nuclear translocator
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATG10 autophagy related 10
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AURKA aurora kinase A
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDC25C cell division cycle 25C
CLEC3B C-type lectin domain family 3, member B
CLTA clathrin, light chain A
COL15A1 collagen, type XV, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DAPK2 death-associated protein kinase 2
DBT dihydrolipoamide branched chain transacylase E2
DCAF4 DDB1 and CUL4 associated factor 4
DMTN dematin actin binding protein
DSCAM Down syndrome cell adhesion molecule
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPN2 epsin 2
FCF1 FCF1 rRNA-processing protein
FLJ21369 uncharacterized protein FLJ21369
FRMD1 FERM domain containing 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GEMIN7 gem (nuclear organelle) associated protein 7
GLRA1 glycine receptor, alpha 1
GPR1 G protein-coupled receptor 1
GPR137B G protein-coupled receptor 137B
GPX2 glutathione peroxidase 2
GTPBP1 GTP binding protein 1
HIST1H2AG histone cluster 1, H2ag
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HYI hydroxypyruvate isomerase (putative)
ICAM1 intercellular adhesion molecule 1
IGHD immunoglobulin heavy constant delta
INSL4 insulin-like 4 (placenta)
JAK3 Janus kinase 3
KANK2 KN motif and ankyrin repeat domains 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KHK ketohexokinase (fructokinase)
LARP4B La ribonucleoprotein domain family, member 4B
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MCAM melanoma cell adhesion molecule
MID1 midline 1
MKL2 MKL/myocardin-like 2
MOB3B MOB kinase activator 3B
MYF5 myogenic factor 5
NPR1 natriuretic peptide receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PCNXL2 pecanex-like 2 (Drosophila)
PDCL phosducin-like
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM5 PDZ and LIM domain 5
PEX11A peroxisomal biogenesis factor 11 alpha
POLL polymerase (DNA directed), lambda
PRDM12 PR domain containing 12
PRO2964 uncharacterized protein PRO2964
PTAFR platelet-activating factor receptor
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRF protein tyrosine phosphatase, receptor type, F
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RBKS ribokinase
RBPMS RNA binding protein with multiple splicing
RECQL5 RecQ protein-like 5
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMAD3 SMAD family member 3
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOS2 son of sevenless homolog 2 (Drosophila)
STS steroid sulfatase (microsomal), isozyme S
STX5 syntaxin 5
TBC1D17 TBC1 domain family, member 17
TBL1X transducin (beta)-like 1X-linked
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCF3 transcription factor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEF thyrotrophic embryonic factor
TEX15 testis expressed 15
TIMP2 TIMP metallopeptidase inhibitor 2
TJAP1 tight junction associated protein 1 (peripheral)
TRAF4 TNF receptor-associated factor 4
TROVE2 TROVE domain family, member 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USH1C Usher syndrome 1C (autosomal recessive, severe)
USP2 ubiquitin specific peptidase 2
ZMYM5 zinc finger, MYM-type 5
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AGO4 argonaute RISC catalytic component 4
APH1B APH1B gamma secretase subunit
ATAT1 alpha tubulin acetyltransferase 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAK1 BCL2-antagonist/killer 1
BSPRY B-box and SPRY domain containing
C1ORF105 chromosome 1 open reading frame 105
C1ORF95 chromosome 1 open reading frame 95
C9ORF9 chromosome 9 open reading frame 9
CAMKMT calmodulin-lysine N-methyltransferase
CCDC85C coiled-coil domain containing 85C
CD34 CD34 molecule
CD82 CD82 molecule
CDA cytidine deaminase
CDR2L cerebellar degeneration-related protein 2-like
CEP97 centrosomal protein 97kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CNPY4 canopy FGF signaling regulator 4
CRELD1 cysteine-rich with EGF-like domains 1
CROT carnitine O-octanoyltransferase
CRY2 cryptochrome circadian clock 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDN dendrin
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOC2A double C2-like domains, alpha
EDC3 enhancer of mRNA decapping 3
EXD3 exonuclease 3'-5' domain containing 3
FAM163A family with sequence similarity 163, member A
FAM184A family with sequence similarity 184, member A
FAM57A family with sequence similarity 57, member A
FANCC Fanconi anemia, complementation group C
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDAP2 ganglioside induced differentiation associated protein 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRIP2 glutamate receptor interacting protein 2
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IPO8 importin 8
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDM8 lysine (K)-specific demethylase 8
KIAA0753 KIAA0753
KLHL26 kelch-like family member 26
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMB2 laminin, beta 2 (laminin S)
LHFP lipoma HMGIC fusion partner
LOC729164 hCG1732469
LRP5 low density lipoprotein receptor-related protein 5
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAST3 microtubule associated serine/threonine kinase 3
MEF2D myocyte enhancer factor 2D
MEGF8 multiple EGF-like-domains 8
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NLRX1 NLR family member X1
NT5M 5',3'-nucleotidase, mitochondrial
PDE12 phosphodiesterase 12
PEAK1 pseudopodium-enriched atypical kinase 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGP phosphoglycolate phosphatase
PIAS3 protein inhibitor of activated STAT, 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLS1 plastin 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKG2 protein kinase, cGMP-dependent, type II
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF2 ring finger protein 2
RPAP2 RNA polymerase II associated protein 2
SALL2 spalt-like transcription factor 2
SETD1A SET domain containing 1A
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SSTR5 somatostatin receptor 5
STXBP5L syntaxin binding protein 5-like
TCTN2 tectonic family member 2
TMC7 transmembrane channel-like 7
TMEM177 transmembrane protein 177
TOR4A torsin family 4, member A
TUBA4B tubulin, alpha 4b
UCN urocortin
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
VEGFB vascular endothelial growth factor B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZMAT5 zinc finger, matrin-type 5
ZNF16 zinc finger protein 16
ZNF286A zinc finger protein 286A
ZNF324 zinc finger protein 324
ZNF493 zinc finger protein 493
ZNF747 zinc finger protein 747