clebopride-6311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the clebopride-6311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOLD1 apolipoprotein L domain containing 1
ATXN2L ataxin 2-like
B3GAT3 beta-1,3-glucuronyltransferase 3
BTD biotinidase
C14ORF93 chromosome 14 open reading frame 93
C17ORF85 chromosome 17 open reading frame 85
C19ORF60 chromosome 19 open reading frame 60
C3 complement component 3
CCDC71 coiled-coil domain containing 71
CDH7 cadherin 7, type 2
CDK9 cyclin-dependent kinase 9
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP69 cilia and flagella associated protein 69
COL8A2 collagen, type VIII, alpha 2
COX4I1 cytochrome c oxidase subunit IV isoform 1
CTNS cystinosin, lysosomal cystine transporter
CTSF cathepsin F
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EML2 echinoderm microtubule associated protein like 2
ETNK2 ethanolamine kinase 2
FBXL7 F-box and leucine-rich repeat protein 7
FBXO11 F-box protein 11
FGFR1 fibroblast growth factor receptor 1
GPM6B glycoprotein M6B
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHMBP2 immunoglobulin mu binding protein 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL11 interleukin 11
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LRP6 low density lipoprotein receptor-related protein 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED28 mediator complex subunit 28
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NID1 nidogen 1
NOTCH4 notch 4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRP2 neuropilin 2
NUP160 nucleoporin 160kDa
OCLM oculomedin
OVOL2 ovo-like zinc finger 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PNMA2 paraneoplastic Ma antigen 2
POMT2 protein-O-mannosyltransferase 2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCH1 patched 1
PTCRA pre T-cell antigen receptor alpha
PTK6 protein tyrosine kinase 6
PTK7 protein tyrosine kinase 7 (inactive)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAD23B RAD23 homolog B (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGCC regulator of cell cycle
SIX2 SIX homeobox 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC46A3 solute carrier family 46, member 3
SMAD1 SMAD family member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SUGCT succinyl-CoA:glutarate-CoA transferase
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SVIL supervillin
TBCD tubulin folding cofactor D
TMEM180 transmembrane protein 180
TPMT thiopurine S-methyltransferase
TRABD TraB domain containing
VGLL3 vestigial-like family member 3
WDR76 WD repeat domain 76
WSB1 WD repeat and SOCS box containing 1
WWOX WW domain containing oxidoreductase
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP36L1 ZFP36 ring finger protein-like 1
ZMAT5 zinc finger, matrin-type 5
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMT aminomethyltransferase
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF73 chromosome 11 open reading frame 73
C5 complement component 5
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC88C coiled-coil domain containing 88C
CCNL2 cyclin L2
CD70 CD70 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC45 cell division cycle 45
CDKL3 cyclin-dependent kinase-like 3
CHKB choline kinase beta
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
DCAF17 DDB1 and CUL4 associated factor 17
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSPP dentin sialophosphoprotein
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ERCC2 excision repair cross-complementation group 2
FAM50B family with sequence similarity 50, member B
FOXN2 forkhead box N2
FSD1 fibronectin type III and SPRY domain containing 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GJC1 gap junction protein, gamma 1, 45kDa
HIST1H2AM histone cluster 1, H2am
HLX H2.0-like homeobox
HOOK2 hook microtubule-tethering protein 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11RA interleukin 11 receptor, alpha
IRF1 interferon regulatory factor 1
KCTD7 potassium channel tetramerization domain containing 7
LMO7 LIM domain 7
LY6E lymphocyte antigen 6 complex, locus E
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MEIS1 Meis homeobox 1
MID1IP1 MID1 interacting protein 1
MOXD1 monooxygenase, DBH-like 1
MRPL2 mitochondrial ribosomal protein L2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NHEJ1 nonhomologous end-joining factor 1
NLGN1 neuroligin 1
NOTCH1 notch 1
ONECUT2 one cut homeobox 2
PCDHGB5 protocadherin gamma subfamily B, 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFRL platelet-derived growth factor receptor-like
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKN1 protein kinase N1
PLCD1 phospholipase C, delta 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PTCD2 pentatricopeptide repeat domain 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIBC2 RIB43A domain with coiled-coils 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPE ribulose-5-phosphate-3-epimerase
RPGR retinitis pigmentosa GTPase regulator
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STIM1 stromal interaction molecule 1
TAGLN3 transgelin 3
THBS3 thrombospondin 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TLN1 talin 1
TMEM242 transmembrane protein 242
TMEM57 transmembrane protein 57
TSSC4 tumor suppressing subtransferable candidate 4
TTC26 tetratricopeptide repeat domain 26
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
ULBP2 UL16 binding protein 2
URM1 ubiquitin related modifier 1
XAB2 XPA binding protein 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862