citalopram-4555 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the citalopram-4555 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
AMT aminomethyltransferase
APOC1 apolipoprotein C-I
ARPIN actin-related protein 2/3 complex inhibitor
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BMP10 bone morphogenetic protein 10
BTG2 BTG family, member 2
BTN3A2 butyrophilin, subfamily 3, member A2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSF1 colony stimulating factor 1 (macrophage)
CST4 cystatin S
CTF1 cardiotrophin 1
CTRC chymotrypsin C (caldecrin)
CXCR2 chemokine (C-X-C motif) receptor 2
DGCR2 DiGeorge syndrome critical region gene 2
DOK4 docking protein 4
DRD2 dopamine receptor D2
DST dystonin
EMX1 empty spiracles homeobox 1
EPN1 epsin 1
ERCC4 excision repair cross-complementation group 4
FGF5 fibroblast growth factor 5
FH fumarate hydratase
FRMD1 FERM domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GK glycerol kinase
GPATCH4 G patch domain containing 4
GPR161 G protein-coupled receptor 161
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2BM histone cluster 1, H2bm
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IPCEF1 interaction protein for cytohesin exchange factors 1
JAK3 Janus kinase 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1467 KIAA1467
KRT14 keratin 14, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00216 long intergenic non-protein coding RNA 216
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MERTK MER proto-oncogene, tyrosine kinase
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MOCS1 molybdenum cofactor synthesis 1
MTMR3 myotubularin related protein 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA2 nuclear receptor coactivator 2
NGF nerve growth factor (beta polypeptide)
NKTR natural killer cell triggering receptor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIP prolactin-induced protein
PITX1 paired-like homeodomain 1
POLG polymerase (DNA directed), gamma
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTAFR platelet-activating factor receptor
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PURA purine-rich element binding protein A
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB2A RAB2A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RASA3 RAS p21 protein activator 3
RBM26 RNA binding motif protein 26
RPS3A ribosomal protein S3A
RUNDC3A RUN domain containing 3A
SEC24D SEC24 family member D
SH3GL3 SH3-domain GRB2-like 3
SHOX2 short stature homeobox 2
SIRT5 sirtuin 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SSBP2 single-stranded DNA binding protein 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT12 synaptotagmin XII
TBXA2R thromboxane A2 receptor
TLE4 transducin-like enhancer of split 4
TLN2 talin 2
TMPRSS2 transmembrane protease, serine 2
TNIK TRAF2 and NCK interacting kinase
TTLL3 tubulin tyrosine ligase-like family member 3
TXK TXK tyrosine kinase
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WT1-AS WT1 antisense RNA
ZER1 zyg-11 related, cell cycle regulator
ZFHX2 zinc finger homeobox 2
ZNF219 zinc finger protein 219
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ANP32A-IT1 ANP32A intronic transcript 1
APOL6 apolipoprotein L, 6
BAHD1 bromo adjacent homology domain containing 1
BEND5 BEN domain containing 5
C19ORF54 chromosome 19 open reading frame 54
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
C5ORF42 chromosome 5 open reading frame 42
C5ORF45 chromosome 5 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CA9 carbonic anhydrase IX
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD101 CD101 molecule
CEP131 centrosomal protein 131kDa
CLEC16A C-type lectin domain family 16, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTNAP3B contactin associated protein-like 3B
COL9A2 collagen, type IX, alpha 2
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE7 copine VII
CRYBB2P1 crystallin, beta B2 pseudogene 1
DENND4A DENN/MADD domain containing 4A
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM53B family with sequence similarity 53, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKRP fukutin related protein
FOXN2 forkhead box N2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLDC glycine dehydrogenase (decarboxylating)
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HIST1H2BO histone cluster 1, H2bo
HMHA1 histocompatibility (minor) HA-1
IPO8 importin 8
IRF1 interferon regulatory factor 1
ISL1 ISL LIM homeobox 1
ITPKC inositol-trisphosphate 3-kinase C
KLHDC4 kelch domain containing 4
KLHL28 kelch-like family member 28
LOC100286895 cell division cycle 27 homolog pseudogene
LOC390998 ribosomal protein L10 pseudogene
LYPD3 LY6/PLAUR domain containing 3
MCC mutated in colorectal cancers
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
NACA2 nascent polypeptide-associated complex alpha subunit 2
NID2 nidogen 2 (osteonidogen)
NRTN neurturin
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OVGP1 oviductal glycoprotein 1, 120kDa
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PCOLCE procollagen C-endopeptidase enhancer
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTK7 protein tyrosine kinase 7 (inactive)
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRS protein tyrosine phosphatase, receptor type, S
RAI2 retinoic acid induced 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RUNDC3B RUN domain containing 3B
RUNX1-IT1 RUNX1 intronic transcript 1
S100A3 S100 calcium binding protein A3
SCG5 secretogranin V
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD1A SET domain containing 1A
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SNORA21 small nucleolar RNA, H/ACA box 21
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TENM1 teneurin transmembrane protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSKU tsukushi, small leucine rich proteoglycan
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR25 WD repeat domain 25
WNT10B wingless-type MMTV integration site family, member 10B
YOD1 YOD1 deubiquitinase
ZNF557 zinc finger protein 557