cinchonine-2789 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cinchonine-2789 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
APLP2 amyloid beta (A4) precursor-like protein 2
ARNT aryl hydrocarbon receptor nuclear translocator
ATRNL1 attractin-like 1
BAIAP3 BAI1-associated protein 3
BTD biotinidase
C2ORF27A chromosome 2 open reading frame 27A
C2ORF68 chromosome 2 open reading frame 68
C5AR1 complement component 5a receptor 1
CABIN1 calcineurin binding protein 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD22 CD22 molecule
CD34 CD34 molecule
CD53 CD53 molecule
CD8A CD8a molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CRELD1 cysteine-rich with EGF-like domains 1
CTSF cathepsin F
CYLD cylindromatosis (turban tumor syndrome)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEPDC5 DEP domain containing 5
DFNB31 deafness, autosomal recessive 31
DLX2 distal-less homeobox 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPYSL4 dihydropyrimidinase-like 4
ERAP1 endoplasmic reticulum aminopeptidase 1
EXD3 exonuclease 3'-5' domain containing 3
EXOC7 exocyst complex component 7
FGA fibrinogen alpha chain
FGFR1 fibroblast growth factor receptor 1
FMO5 flavin containing monooxygenase 5
HBEGF heparin-binding EGF-like growth factor
HDAC7 histone deacetylase 7
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
HNF1B HNF1 homeobox B
HRASLS2 HRAS-like suppressor 2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ICA1 islet cell autoantigen 1, 69kDa
IL17RC interleukin 17 receptor C
ING1 inhibitor of growth family, member 1
KAT6A K(lysine) acetyltransferase 6A
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA1456 KIAA1456
KRT6B keratin 6B, type II
LAPTM5 lysosomal protein transmembrane 5
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFGE8 milk fat globule-EGF factor 8 protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP3 matrix metallopeptidase 3
MRC2 mannose receptor, C type 2
NCR2 natural cytotoxicity triggering receptor 2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NPY4R neuropeptide Y receptor Y4
NR4A1 nuclear receptor subfamily 4, group A, member 1
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX14 peroxisomal biogenesis factor 14
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRF1 perforin 1 (pore forming protein)
PTK2B protein tyrosine kinase 2 beta
REPS1 RALBP1 associated Eps domain containing 1
RNF19B ring finger protein 19B
RNF39 ring finger protein 39
RUNX1 runt-related transcription factor 1
SDC2 syndecan 2
SDF4 stromal cell derived factor 4
SHOX2 short stature homeobox 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35E2 solute carrier family 35, member E2
SLC41A3 solute carrier family 41, member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D2 TBC1 domain family, member 2
THTPA thiamine triphosphatase
TOP3B topoisomerase (DNA) III beta
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC9 tetratricopeptide repeat domain 9
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WDR78 WD repeat domain 78
ZBTB40 zinc finger and BTB domain containing 40
ZCCHC24 zinc finger, CCHC domain containing 24
ZMYND8 zinc finger, MYND-type containing 8
ZNF175 zinc finger protein 175
ZNF37BP zinc finger protein 37B, pseudogene
ZNF695 zinc finger protein 695
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSF2 acyl-CoA synthetase family member 2
ALAS1 5'-aminolevulinate synthase 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CDK3 cyclin-dependent kinase 3
CEMIP cell migration inducing protein, hyaluronan binding
CENPO centromere protein O
CIC capicua transcriptional repressor
CLDN15 claudin 15
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYHR1 cysteine/histidine-rich 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
FAM118A family with sequence similarity 118, member A
FAM184A family with sequence similarity 184, member A
FCHO1 FCH domain only 1
FLCN folliculin
FRAS1 Fraser extracellular matrix complex subunit 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GAS2 growth arrest-specific 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRTP1 growth hormone regulated TBC protein 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H3E histone cluster 1, H3e
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA4 homeobox A4
HYAL1 hyaluronoglucosaminidase 1
IL17RA interleukin 17 receptor A
INPP1 inositol polyphosphate-1-phosphatase
INPP5J inositol polyphosphate-5-phosphatase J
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNK12 potassium channel, two pore domain subfamily K, member 12
LINC00597 long intergenic non-protein coding RNA 597
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP6D1 MAP6 domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MT1H metallothionein 1H
NBEAL2 neurobeachin-like 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLXNA3 plexin A3
POLL polymerase (DNA directed), lambda
POTEKP POTE ankyrin domain family, member K, pseudogene
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF31 ring finger protein 31
RPL23AP32 ribosomal protein L23a pseudogene 32
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCRN3 secernin 3
SIRT6 sirtuin 6
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP1 Sp1 transcription factor
SPON2 spondin 2, extracellular matrix protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT17 synaptotagmin XVII
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TFRC transferrin receptor
TMSB15A thymosin beta 15a
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOR4A torsin family 4, member A
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
VEZT vezatin, adherens junctions transmembrane protein
WDR33 WD repeat domain 33
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB33 zinc finger and BTB domain containing 33
ZBTB6 zinc finger and BTB domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF160 zinc finger protein 160
ZNF329 zinc finger protein 329
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF804A zinc finger protein 804A