cinchonidine-7190 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cinchonidine-7190 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARNT aryl hydrocarbon receptor nuclear translocator
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP3 caspase 3, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CD24 CD24 molecule
CDC25C cell division cycle 25C
CFLAR CASP8 and FADD-like apoptosis regulator
CLCN6 chloride channel, voltage-sensitive 6
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DLL3 delta-like 3 (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELSPBP1 epididymal sperm binding protein 1
EXOC7 exocyst complex component 7
EXTL3 exostosin-like glycosyltransferase 3
FAM189A2 family with sequence similarity 189, member A2
FAS Fas cell surface death receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPATCH2L G patch domain containing 2-like
GRB10 growth factor receptor-bound protein 10
GRM4 glutamate receptor, metabotropic 4
HIPK3 homeodomain interacting protein kinase 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HRK harakiri, BCL2 interacting protein
IL20RA interleukin 20 receptor, alpha
IL6ST interleukin 6 signal transducer
INO80B INO80 complex subunit B
KDM5B lysine (K)-specific demethylase 5B
KRT17 keratin 17, type I
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBNL2 muscleblind-like splicing regulator 2
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MFN2 mitofusin 2
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCOA2 nuclear receptor coactivator 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA6 protocadherin alpha 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PODXL2 podocalyxin-like 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
QKI QKI, KH domain containing, RNA binding
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB6A RAB6A, member RAS oncogene family
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RARG retinoic acid receptor, gamma
RECQL5 RecQ protein-like 5
RNASEH2B ribonuclease H2, subunit B
RNGTT RNA guanylyltransferase and 5'-phosphatase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RUNDC3A RUN domain containing 3A
SCAPER S-phase cyclin A-associated protein in the ER
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SKIL SKI-like proto-oncogene
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC39A9 solute carrier family 39, member 9
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SNUPN snurportin 1
SP100 SP100 nuclear antigen
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAC SH3 and cysteine rich domain
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAGLN3 transgelin 3
TBL1Y transducin (beta)-like 1, Y-linked
TESC tescalcin
THRA thyroid hormone receptor, alpha
TMPRSS2 transmembrane protease, serine 2
TRIM10 tripartite motif containing 10
TRIM23 tripartite motif containing 23
UTRN utrophin
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YY2 YY2 transcription factor
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF287 zinc finger protein 287
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACIN1 apoptotic chromatin condensation inducer 1
AEN apoptosis enhancing nuclease
AHDC1 AT hook, DNA binding motif, containing 1
ALAS1 5'-aminolevulinate synthase 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD36 ankyrin repeat domain 36
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCL9 B-cell CLL/lymphoma 9
C16ORF45 chromosome 16 open reading frame 45
C17ORF70 chromosome 17 open reading frame 70
C7ORF43 chromosome 7 open reading frame 43
CASKIN2 CASK interacting protein 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CORO2A coronin, actin binding protein, 2A
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
DGKZ diacylglycerol kinase, zeta
DNAAF2 dynein, axonemal, assembly factor 2
DPH2 DPH2 homolog (S. cerevisiae)
DSN1 DSN1, MIS12 kinetochore complex component
DSPP dentin sialophosphoprotein
EFCAB2 EF-hand calcium binding domain 2
ELP3 elongator acetyltransferase complex subunit 3
FAM102A family with sequence similarity 102, member A
FAM188A family with sequence similarity 188, member A
FAM189B family with sequence similarity 189, member B
FCHO1 FCH domain only 1
FHOD1 formin homology 2 domain containing 1
GALK1 galactokinase 1
GRWD1 glutamate-rich WD repeat containing 1
HPS6 Hermansky-Pudlak syndrome 6
ICK intestinal cell (MAK-like) kinase
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
IPO8 importin 8
KRT13 keratin 13, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
PANX1 pannexin 1
PAQR6 progestin and adipoQ receptor family member VI
PARP16 poly (ADP-ribose) polymerase family, member 16
PLAC8 placenta-specific 8
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POR P450 (cytochrome) oxidoreductase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP6R3 protein phosphatase 6, regulatory subunit 3
RAB8B RAB8B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RNF31 ring finger protein 31
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SALL2 spalt-like transcription factor 2
SCAMP4 secretory carrier membrane protein 4
SH2B3 SH2B adaptor protein 3
SKA1 spindle and kinetochore associated complex subunit 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TFRC transferrin receptor
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TNRC6B trinucleotide repeat containing 6B
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRIM52 tripartite motif containing 52
TSPAN1 tetraspanin 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN6 UBX domain protein 6
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VGF VGF nerve growth factor inducible
WDR60 WD repeat domain 60
XYLT2 xylosyltransferase II
YEATS4 YEATS domain containing 4
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC24 zinc finger, DHHC-type containing 24
ZFHX3 zinc finger homeobox 3
ZNF32 zinc finger protein 32
ZNHIT2 zinc finger, HIT-type containing 2