ciclosporin-602 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ciclosporin-602 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AHCYL1 adenosylhomocysteinase-like 1
AIM1L absent in melanoma 1-like
AIM2 absent in melanoma 2
AQP3 aquaporin 3 (Gill blood group)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AVPR1B arginine vasopressin receptor 1B
B9D1 B9 protein domain 1
C10ORF76 chromosome 10 open reading frame 76
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF156 chromosome 9 open reading frame 156
CADM1 cell adhesion molecule 1
CAMK1G calcium/calmodulin-dependent protein kinase IG
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC87 coiled-coil domain containing 87
CD101 CD101 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL5A3 collagen, type V, alpha 3
COMT catechol-O-methyltransferase
CPT2 carnitine palmitoyltransferase 2
DENND2A DENN/MADD domain containing 2A
DRP2 dystrophin related protein 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERCC4 excision repair cross-complementation group 4
FBLN1 fibulin 1
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FRMD1 FERM domain containing 1
GLRA2 glycine receptor, alpha 2
GOLPH3L golgi phosphoprotein 3-like
GPR3 G protein-coupled receptor 3
GPRC5D G protein-coupled receptor, class C, group 5, member D
GYPB glycophorin B (MNS blood group)
HLA-G major histocompatibility complex, class I, G
HNF4A hepatocyte nuclear factor 4, alpha
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IFFO1 intermediate filament family orphan 1
IL1B interleukin 1, beta
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITSN2 intersectin 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIF16B kinesin family member 16B
KIF5A kinesin family member 5A
LGALS8 lectin, galactoside-binding, soluble, 8
LOC647070 uncharacterized LOC647070
MAGED2 melanoma antigen family D2
MAN1C1 mannosidase, alpha, class 1C, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MED18 mediator complex subunit 18
MGC2889 uncharacterized protein MGC2889
MLN motilin
MNAT1 MNAT CDK-activating kinase assembly factor 1
MSH3 mutS homolog 3
MTUS1 microtubule associated tumor suppressor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPAT nuclear protein, ataxia-telangiectasia locus
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OLFM1 olfactomedin 1
PAIP2B poly(A) binding protein interacting protein 2B
PEX11A peroxisomal biogenesis factor 11 alpha
PHF20 PHD finger protein 20
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLAC1 placenta-specific 1
RAB11B RAB11B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RIMS2 regulating synaptic membrane exocytosis 2
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RORC RAR-related orphan receptor C
RPL35A ribosomal protein L35a
RRBP1 ribosome binding protein 1
RUNX1 runt-related transcription factor 1
RWDD2A RWD domain containing 2A
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEZ6L seizure related 6 homolog (mouse)-like
SH2D3C SH2 domain containing 3C
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC43A3 solute carrier family 43, member 3
SLPI secretory leukocyte peptidase inhibitor
SPTB spectrin, beta, erythrocytic
STAC SH3 and cysteine rich domain
STARD5 StAR-related lipid transfer (START) domain containing 5
SUSD4 sushi domain containing 4
TCL1A T-cell leukemia/lymphoma 1A
TMEM176A transmembrane protein 176A
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53I11 tumor protein p53 inducible protein 11
TSPAN32 tetraspanin 32
TTC3 tetratricopeptide repeat domain 3
TYR tyrosinase
VENTX VENT homeobox
WDR48 WD repeat domain 48
WWOX WW domain containing oxidoreductase
ZC3H12A zinc finger CCCH-type containing 12A
ZNF473 zinc finger protein 473
ZNF91 zinc finger protein 91
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
AKIRIN1 akirin 1
ALLC allantoicase
AMDHD2 amidohydrolase domain containing 2
ASUN asunder spermatogenesis regulator
ATF7IP2 activating transcription factor 7 interacting protein 2
BRIX1 BRX1, biogenesis of ribosomes
C10ORF88 chromosome 10 open reading frame 88
C16ORF59 chromosome 16 open reading frame 59
CEP131 centrosomal protein 131kDa
CLCN2 chloride channel, voltage-sensitive 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COLEC11 collectin sub-family member 11
CRY1 cryptochrome circadian clock 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND4C DENN/MADD domain containing 4C
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSCAM Down syndrome cell adhesion molecule
ECT2 epithelial cell transforming 2
EGFL7 EGF-like-domain, multiple 7
EMILIN2 elastin microfibril interfacer 2
EPX eosinophil peroxidase
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
FIP1L1 factor interacting with PAPOLA and CPSF1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPATCH1 G patch domain containing 1
GPHN gephyrin
HHLA1 HERV-H LTR-associating 1
HOXC4 homeobox C4
HPSE heparanase
IGFBP6 insulin-like growth factor binding protein 6
IL2RB interleukin 2 receptor, beta
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JOSD1 Josephin domain containing 1
KIFC3 kinesin family member C3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRI1 KRI1 homolog (S. cerevisiae)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAD2L1BP MAD2L1 binding protein
MARC1 mitochondrial amidoxime reducing component 1
MAST3 microtubule associated serine/threonine kinase 3
METTL8 methyltransferase like 8
MEX3C mex-3 RNA binding family member C
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MOB3B MOB kinase activator 3B
MOGAT2 monoacylglycerol O-acyltransferase 2
MYL12B myosin, light chain 12B, regulatory
MYO1D myosin ID
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NMU neuromedin U
NXN nucleoredoxin
OLFML2B olfactomedin-like 2B
OR10H3 olfactory receptor, family 10, subfamily H, member 3
PADI1 peptidyl arginine deiminase, type I
PARVA parvin, alpha
PCYOX1 prenylcysteine oxidase 1
PFAS phosphoribosylformylglycinamidine synthase
PHF21A PHD finger protein 21A
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCD1 phospholipase C, delta 1
PMP22 peripheral myelin protein 22
PPCS phosphopantothenoylcysteine synthetase
PRSS53 protease, serine, 53
PTDSS2 phosphatidylserine synthase 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
QTRT1 queuine tRNA-ribosyltransferase 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCOR3 REST corepressor 3
RFWD3 ring finger and WD repeat domain 3
RRP1 ribosomal RNA processing 1
SLC17A4 solute carrier family 17, member 4
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SNX6 sorting nexin 6
TARBP1 TAR (HIV-1) RNA binding protein 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM131 transmembrane protein 131
TMEM206 transmembrane protein 206
TMEM50A transmembrane protein 50A
TMOD3 tropomodulin 3 (ubiquitous)
TRIM8 tripartite motif containing 8
TSC22D4 TSC22 domain family, member 4
UBXN2B UBX domain protein 2B
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
XPA xeroderma pigmentosum, complementation group A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF354A zinc finger protein 354A
ZNF394 zinc finger protein 394