chronic myeloproliferative disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A myeloma that is characterized by a group of slow growing blood cancers in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood. (Human Disease Ontology, DOID_2226)
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Genes

108 genes co-occuring with the disease chronic myeloproliferative disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
JAK2 Janus kinase 2 2.25213
THPO thrombopoietin 1.68498
MPL MPL proto-oncogene, thrombopoietin receptor 1.526
BCR breakpoint cluster region 1.44518
CD177 CD177 molecule 1.32236
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.15112
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 1.06942
FGFR1 fibroblast growth factor receptor 1 0.974221
ZNF577 zinc finger protein 577 0.960378
TOP1MT topoisomerase (DNA) I, mitochondrial 0.958287
ZMYM2 zinc finger, MYM-type 2 0.944521
CD34 CD34 molecule 0.930414
IFNA1 interferon, alpha 1 0.901978
FIP1L1 factor interacting with PAPOLA and CPSF1 0.889668
ZNF77 zinc finger protein 77 0.843802
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.834378
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.806898
VWF von Willebrand factor 0.799103
ETV6 ets variant 6 0.796642
FAIM Fas apoptotic inhibitory molecule 0.787623
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.767576
CCDC88C coiled-coil domain containing 88C 0.761047
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.730571
RPN1 ribophorin I 0.71078
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.710378
PGK1 phosphoglycerate kinase 1 0.700321
IFNA2 interferon, alpha 2 0.666358
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.656441
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.656046
TGFB1 transforming growth factor, beta 1 0.648928
CD36 CD36 molecule (thrombospondin receptor) 0.643797
MPO myeloperoxidase 0.590558
FGF2 fibroblast growth factor 2 (basic) 0.587833
ELN elastin 0.586665
LHX2 LIM homeobox 2 0.580828
CAPRIN2 caprin family member 2 0.560227
SESN2 sestrin 2 0.538118
WIF1 WNT inhibitory factor 1 0.533088
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.527676
PF4 platelet factor 4 0.526518
FEN1 flap structure-specific endonuclease 1 0.504973
F8 coagulation factor VIII, procoagulant component 0.498849
RXRB retinoid X receptor, beta 0.493503
TBXA2R thromboxane A2 receptor 0.493503
VAV1 vav 1 guanine nucleotide exchange factor 0.479807
FLT3 fms-related tyrosine kinase 3 0.455601
PGM1 phosphoglucomutase 1 0.454847
ALPPL2 alkaline phosphatase, placental-like 2 0.444676
ALPP alkaline phosphatase, placental 0.4443
ALPL alkaline phosphatase, liver/bone/kidney 0.443923
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.440538
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.438658
PTH parathyroid hormone 0.42289
SOCS3 suppressor of cytokine signaling 3 0.42139
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.420641
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.419892
IGHA1 immunoglobulin heavy constant alpha 1 0.418394
LAT linker for activation of T cells 0.415773
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.378885
BCAM basal cell adhesion molecule (Lutheran blood group) 0.363347
XAF1 XIAP associated factor 1 0.349349
MATN1 matrilin 1, cartilage matrix protein 0.347144
NIN ninein (GSK3B interacting protein) 0.333218
PLAU plasminogen activator, urokinase 0.326646
SFRP5 secreted frizzled-related protein 5 0.311377
SCARB2 scavenger receptor class B, member 2 0.307757
CNTLN centlein, centrosomal protein 0.302337
CD68 CD68 molecule 0.300533
AGO2 argonaute RISC catalytic component 2 0.295132
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.289744
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.277227
CD9 CD9 molecule 0.27687
EFNA5 ephrin-A5 0.276514
RARS arginyl-tRNA synthetase 0.266913
OPRK1 opioid receptor, kappa 1 0.26514
SCARB1 scavenger receptor class B, member 1 0.254183
S100A10 S100 calcium binding protein A10 0.248203
BCL2L1 BCL2-like 1 0.241546
SFRP4 secreted frizzled-related protein 4 0.238752
CRABP2 cellular retinoic acid binding protein 2 0.238054
FKBP5 FK506 binding protein 5 0.232489
SPAG9 sperm associated antigen 9 0.227988
PRAME preferentially expressed antigen in melanoma 0.225573
HRAS Harvey rat sarcoma viral oncogene homolog 0.210589
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.208579
TP53 tumor protein p53 0.200656
TFG TRK-fused gene 0.196779
PNPLA6 patatin-like phospholipase domain containing 6 0.189244
SFRP2 secreted frizzled-related protein 2 0.185016
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.185016
IL6 interleukin 6 0.176757
HBA1 hemoglobin, alpha 1 0.170544
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.164149
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.162908
RUNX1 runt-related transcription factor 1 0.158778
HBA2 hemoglobin, alpha 2 0.158434
SMAD4 SMAD family member 4 0.144279
CDH13 cadherin 13 0.144096
IGLV2-8 immunoglobulin lambda variable 2-8 0.143892
HDC histidine decarboxylase 0.143616
TYK2 tyrosine kinase 2 0.143464
TET2 tet methylcytosine dioxygenase 2 0.143247
SPTA1 spectrin, alpha, erythrocytic 1 0.143036
SFRP1 secreted frizzled-related protein 1 0.142688
ANG angiogenin, ribonuclease, RNase A family, 5 0.141876
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.141749
COX5A cytochrome c oxidase subunit Va 0.141679
PROS1 protein S (alpha) 0.141137