chromosomal breakage induced by crosslinking agents Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Increased amount of chromosomal breaks in cultured blood lymphocytes or other cells induced by treatment with DNA cross-linking agents such as diepoxybutane and mitomycin C. (Human Phenotype Ontology, HP_0003221)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0003221
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Genes

8 genes associated with the chromosomal breakage induced by crosslinking agents phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
FANCA Fanconi anemia, complementation group A
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCI Fanconi anemia, complementation group I
PALB2 partner and localizer of BRCA2