chromaffin granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. (Gene Ontology, GO_0042583)
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Genes

96 proteins co-occuring with the chromaffin granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.42082
CHGA chromogranin A 2.18006
PENK proenkephalin 2.17786
CHGB chromogranin B 1.99548
ANXA7 annexin A7 1.63896
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.50453
SCG2 secretogranin II 1.47514
DNAH8 dynein, axonemal, heavy chain 8 1.40634
CPE carboxypeptidase E 1.39907
CPA6 carboxypeptidase A6 1.18235
CPB1 carboxypeptidase B1 (tissue) 1.10002
PNMT phenylethanolamine N-methyltransferase 1.07359
CGB7 chorionic gonadotropin, beta polypeptide 7 1.06853
CGB5 chorionic gonadotropin, beta polypeptide 5 1.06853
NPY neuropeptide Y 1.06549
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.06549
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.06448
CGB chorionic gonadotropin, beta polypeptide 1.0569
CGB8 chorionic gonadotropin, beta polypeptide 8 1.05438
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 1.00497
NPS neuropeptide S 0.985367
CYB561A3 cytochrome b561 family, member A3 0.970814
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.850665
ANXA2 annexin A2 0.841023
ANXA1 annexin A1 0.838728
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.771819
ANXA4 annexin A4 0.770451
TH tyrosine hydroxylase 0.769539
CYBRD1 cytochrome b reductase 1 0.764527
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.757707
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.757253
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.757253
PDYN prodynorphin 0.742318
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 0.719906
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 0.69164
ATP11A ATPase, class VI, type 11A 0.69164
SYP synaptophysin 0.681155
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.667693
MGAM maltase-glucoamylase 0.665096
RAB3A RAB3A, member RAS oncogene family 0.661208
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.660776
PCSK2 proprotein convertase subtilisin/kexin type 2 0.620954
NGF nerve growth factor (beta polypeptide) 0.596014
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 0.595173
ANXA6 annexin A6 0.593072
NYNRIN NYN domain and retroviral integrase containing 0.579669
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.57008
POMC proopiomelanocortin 0.532488
CCDC27 coiled-coil domain containing 27 0.51694
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.490135
LPO lactoperoxidase 0.481258
ACHE acetylcholinesterase (Yt blood group) 0.468001
PAM peptidylglycine alpha-amidating monooxygenase 0.426318
UNC13B unc-13 homolog B (C. elegans) 0.415728
PCSK1 proprotein convertase subtilisin/kexin type 1 0.391615
MIR4315-2 microRNA 4315-2 0.386208
MIR4315-1 microRNA 4315-1 0.386208
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.381969
SCIN scinderin 0.35899
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.353282
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.340395
ERF Ets2 repressor factor 0.328708
INS insulin 0.324951
SCG5 secretogranin V 0.31783
NSF N-ethylmaleimide-sensitive factor 0.307377
TAC1 tachykinin, precursor 1 0.30626
VAMP3 vesicle-associated membrane protein 3 0.301797
STX1A syntaxin 1A (brain) 0.296601
AVP arginine vasopressin 0.29586
PLA2G1B phospholipase A2, group IB (pancreas) 0.283295
PRCD progressive rod-cone degeneration 0.282926
UNC13A unc-13 homolog A (C. elegans) 0.280716
SYT1 synaptotagmin I 0.274468
RPH3A rabphilin 3A 0.2708
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.263485
STMN3 stathmin-like 3 0.261296
APP amyloid beta (A4) precursor protein 0.259109
PHOX2A paired-like homeobox 2a 0.252927
CTSD cathepsin D 0.245685
PLA2G15 phospholipase A2, group XV 0.245685
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.230958
ASCL1 achaete-scute family bHLH transcription factor 1 0.230245
GSN gelsolin 0.229176
HAND2 heart and neural crest derivatives expressed 2 0.196669
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.190495
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.18859
NTS neurotensin 0.18702
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.183631
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.178877
FURIN furin (paired basic amino acid cleaving enzyme) 0.175188
ARF6 ADP-ribosylation factor 6 0.170371
OCM oncomodulin 0.164542
RAB3C RAB3C, member RAS oncogene family 0.16298
RGS19 regulator of G-protein signaling 19 0.160254
MGLL monoglyceride lipase 0.159856
OCM2 oncomodulin 2 0.156513