chondrosarcoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A connective tissue cancer that has_material_basis_in cells derived from transformed cells that produce cartilage. (Human Disease Ontology, DOID_3371)
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Genes

348 genes co-occuring with the disease chondrosarcoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 1.92014
EXT2 exostosin glycosyltransferase 2 1.90288
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.83274
EXT1 exostosin glycosyltransferase 1 1.80201
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 1.68317
ACAN aggrecan 1.6624
SOX9 SRY (sex determining region Y)-box 9 1.29877
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1.24776
FMNL2 formin-like 2 1.22172
LECT1 leukocyte cell derived chemotaxin 1 1.21175
IHH indian hedgehog 1.20915
FMNL1 formin-like 1 1.19661
DAAM2 dishevelled associated activator of morphogenesis 2 1.18453
TFG TRK-fused gene 1.14942
FMNL3 formin-like 3 1.1422
FHDC1 FH2 domain containing 1 1.13585
DIAPH2 diaphanous-related formin 2 1.12909
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.12235
COL2A1 collagen, type II, alpha 1 1.09881
TP53 tumor protein p53 1.07824
FHOD1 formin homology 2 domain containing 1 1.06732
FAM195A family with sequence similarity 195, member A 1.06648
ENO2 enolase 2 (gamma, neuronal) 1.0627
DAAM1 dishevelled associated activator of morphogenesis 1 1.06144
TCF12 transcription factor 12 1.05892
MMP13 matrix metallopeptidase 13 1.05765
FAM86DP family with sequence similarity 86, member D, pseudogene 1.05555
DIAPH1 diaphanous-related formin 1 1.05219
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.994861
TMEM30C transmembrane protein 30C 0.988535
COL27A1 collagen, type XXVII, alpha 1 0.982636
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.982636
MMP1 matrix metallopeptidase 1 0.964148
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.959123
NCOA2 nuclear receptor coactivator 2 0.953273
YEATS2 YEATS domain containing 2 0.937044
CSAG2 CSAG family, member 2 0.922149
CSAG3 CSAG family, member 3 0.922149
CTGF connective tissue growth factor 0.916787
FMN2 formin 2 0.899924
PTHLH parathyroid hormone-like hormone 0.894179
FGF1 fibroblast growth factor 1 (acidic) 0.889668
CSAG1 chondrosarcoma associated gene 1 0.852402
FNBP1 formin binding protein 1 0.844621
ARHGAP23 Rho GTPase activating protein 23 0.840115
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.806077
ARHGAP12 Rho GTPase activating protein 12 0.803616
MTAP methylthioadenosine phosphorylase 0.798692
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.795411
FMN1 formin 1 0.788852
CD99 CD99 molecule 0.788442
DIAPH3 diaphanous-related formin 3 0.785984
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.776977
ARHGAP10 Rho GTPase activating protein 10 0.772479
GLI2 GLI family zinc finger 2 0.772479
CHAD chondroadherin 0.768393
CDKN2A cyclin-dependent kinase inhibitor 2A 0.764718
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.763902
FUS FUS RNA binding protein 0.74761
MMP2 matrix metallopeptidase 2 0.742329
ARHGAP25 Rho GTPase activating protein 25 0.738676
SYP synaptophysin 0.738676
BAX BCL2-associated X protein 0.728952
GLI1 GLI family zinc finger 1 0.714811
TMEM30A transmembrane protein 30A 0.707157
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 0.705949
MYOG myogenin (myogenic factor 4) 0.70233
ARHGAP19 Rho GTPase activating protein 19 0.70233
FNBP4 formin binding protein 4 0.701526
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.699116
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.698715
CREB3L2 cAMP responsive element binding protein 3-like 2 0.6939
SS18 synovial sarcoma translocation, chromosome 18 0.683493
ARHGAP4 Rho GTPase activating protein 4 0.679499
COMP cartilage oligomeric matrix protein 0.678701
ADAMTSL1 ADAMTS-like 1 0.673518
CD44 CD44 molecule (Indian blood group) 0.669936
C11ORF95 chromosome 11 open reading frame 95 0.668742
ALPPL2 alkaline phosphatase, placental-like 2 0.668345
ALPP alkaline phosphatase, placental 0.667947
ALPL alkaline phosphatase, liver/bone/kidney 0.667152
GMIP GEM interacting protein 0.664372
GPR78 G protein-coupled receptor 78 0.650113
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.641827
ARHGAP15 Rho GTPase activating protein 15 0.639463
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.636708
FGFR3 fibroblast growth factor receptor 3 0.632384
MB myoglobin 0.631205
CDK4 cyclin-dependent kinase 4 0.62728
ARHGAP22 Rho GTPase activating protein 22 0.62728
ARHGAP17 Rho GTPase activating protein 17 0.624927
BCL2L1 BCL2-like 1 0.616703
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.614356
HAPLN1 hyaluronan and proteoglycan link protein 1 0.612401
ARHGAP20 Rho GTPase activating protein 20 0.610057
NPM3 nucleophosmin/nucleoplasmin 3 0.604591
NUP107 nucleoporin 107kDa 0.604591
ARHGAP9 Rho GTPase activating protein 9 0.604201
PTCH1 patched 1 0.59952
DAP3 death associated protein 3 0.596792
TMEM30B transmembrane protein 30B 0.595623
CD34 CD34 molecule 0.581606
B3GAT1 beta-1,3-glucuronyltransferase 1 0.575772
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.571107
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.566831
IFT88 intraflagellar transport 88 0.562558
MYOD1 myogenic differentiation 1 0.561392
PDCD5 programmed cell death 5 0.556344
BMP7 bone morphogenetic protein 7 0.556344
EPYC epiphycan 0.55518
AMBP alpha-1-microglobulin/bikunin precursor 0.551686
KRT8 keratin 8, type II 0.550522
M6PR mannose-6-phosphate receptor (cation dependent) 0.546644
FGF2 fibroblast growth factor 2 (basic) 0.545868
RAI14 retinoic acid induced 14 0.536957
ARHGAP24 Rho GTPase activating protein 24 0.535022
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.534248
ETV5 ets variant 5 0.531154
CTAG1A cancer/testis antigen 1A 0.52729
CCNB3 cyclin B3 0.522659
LGALS4 lectin, galactoside-binding, soluble, 4 0.521502
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.519961
ARHGAP21 Rho GTPase activating protein 21 0.516879
MMP9 matrix metallopeptidase 9 0.514956
CTAG1B cancer/testis antigen 1B 0.513417
ALX1 ALX homeobox 1 0.508424
BCAN brevican 0.506507
CDH19 cadherin 19, type 2 0.505739
ARHGAP5 Rho GTPase activating protein 5 0.504973
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.50459
PARVB parvin, beta 0.491215
ARHGAP6 Rho GTPase activating protein 6 0.489311
DDIT3 DNA-damage-inducible transcript 3 0.488169
NOV nephroblastoma overexpressed 0.486646
TGFB1 transforming growth factor, beta 1 0.480186
MOCS1 molybdenum cofactor synthesis 1 0.477151
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.475634
RHOU ras homolog family member U 0.474119
CD24 CD24 molecule 0.473361
SMO smoothened, frizzled class receptor 0.472604
FN1 fibronectin 1 0.466172
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.466172
MATN1 matrilin 1, cartilage matrix protein 0.465038
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.46466
WISP1 WNT1 inducible signaling pathway protein 1 0.462394
EXTL2 exostosin-like glycosyltransferase 2 0.462394
MKL2 MKL/myocardin-like 2 0.462016
STARD8 StAR-related lipid transfer (START) domain containing 8 0.461261
COL12A1 collagen, type XII, alpha 1 0.456732
COL10A1 collagen, type X, alpha 1 0.455601
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.455224
ARHGAP1 Rho GTPase activating protein 1 0.453716
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.453339
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.447311
RUNX2 runt-related transcription factor 2 0.446558
CDX1 caudal type homeobox 1 0.445052
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.442418
COL11A2 collagen, type XI, alpha 2 0.442418
FRS2 fibroblast growth factor receptor substrate 2 0.436026
ARHGAP26 Rho GTPase activating protein 26 0.43227
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.428516
DNM3 dynamin 3 0.42289
JUN jun proto-oncogene 0.418019
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.417644
LXN latexin 0.412405
CYR61 cysteine-rich, angiogenic inducer, 61 0.412031
PCNA proliferating cell nuclear antigen 0.405305
KRT7 keratin 7, type II 0.404931
TFEC transcription factor EC 0.403064
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.401572
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.400453
TNC tenascin C 0.40008
CCND1 cyclin D1 0.398962
NCAM1 neural cell adhesion molecule 1 0.397843
TIMP2 TIMP metallopeptidase inhibitor 2 0.397471
CALCB calcitonin-related polypeptide beta 0.394863
YEATS4 YEATS domain containing 4 0.388909
CLTB clathrin, light chain B 0.379626
MET MET proto-oncogene, receptor tyrosine kinase 0.378885
DNER delta/notch-like EGF repeat containing 0.377773
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.376661
PARD3 par-3 family cell polarity regulator 0.37592
RACGAP1 Rac GTPase activating protein 1 0.372587
PRAME preferentially expressed antigen in melanoma 0.371107
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.365932
EMILIN1 elastin microfibril interfacer 1 0.362239
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.356341
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.353763
SSX1 synovial sarcoma, X breakpoint 1 0.353395
PLAU plasminogen activator, urokinase 0.351555
ITM2B integral membrane protein 2B 0.346409
BGN biglycan 0.346409
EXTL1 exostosin-like glycosyltransferase 1 0.34384
LGALS7 lectin, galactoside-binding, soluble, 7 0.34384
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.337242
FGF17 fibroblast growth factor 17 0.33651
SIX3 SIX homeobox 3 0.335412
FOXL1 forkhead box L1 0.333949
PRRC2A proline-rich coiled-coil 2A 0.333218
CALD1 caldesmon 1 0.3292
GFAP glial fibrillary acidic protein 0.325187
CHGA chromogranin A 0.32373
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.321181
CHN2 chimerin 2 0.317909
CTSS cathepsin S 0.312827
CHN1 chimerin 1 0.309928
FZD8 frizzled class receptor 8 0.309566
FZD9 frizzled class receptor 9 0.30342
AGO2 argonaute RISC catalytic component 2 0.30342
RAB38 RAB38, member RAS oncogene family 0.302698
IGF1 insulin-like growth factor 1 (somatomedin C) 0.300533
HBA1 hemoglobin, alpha 1 0.298011
TRIP10 thyroid hormone receptor interactor 10 0.292257
FZD5 frizzled class receptor 5 0.29118
HBA2 hemoglobin, alpha 2 0.277584
MCM6 minichromosome maintenance complex component 6 0.275445
TAS1R1 taste receptor, type 1, member 1 0.273664
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.272597
TANK TRAF family member-associated NFKB activator 0.269043
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.266558
MMP3 matrix metallopeptidase 3 0.266203
MMP12 matrix metallopeptidase 12 0.26266
ETV4 ets variant 4 0.260891
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.260184
DCN decorin 0.260184
BIN3 bridging integrator 3 0.256299
ADGRG1 adhesion G protein-coupled receptor G1 0.254183
CDC27 cell division cycle 27 0.250311
ZBTB7A zinc finger and BTB domain containing 7A 0.24996
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.24996
ANGPTL2 angiopoietin-like 2 0.249257
PPARG peroxisome proliferator-activated receptor gamma 0.246799
S100P S100 calcium binding protein P 0.244696
PDPN podoplanin 0.243645
GLB1 galactosidase, beta 1 0.242945
FGF8 fibroblast growth factor 8 (androgen-induced) 0.241895
VAMP8 vesicle-associated membrane protein 8 0.241546
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.240847
FZD6 frizzled class receptor 6 0.240497
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.240148
CXCL12 chemokine (C-X-C motif) ligand 12 0.240148
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.239101
COL9A1 collagen, type IX, alpha 1 0.235268
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.230409
FZD2 frizzled class receptor 2 0.229716
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.228333
BGLAP bone gamma-carboxyglutamate (gla) protein 0.227642
SFTPC surfactant protein C 0.226607
PRKCD protein kinase C, delta 0.226607
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.222136
ANXA5 annexin A5 0.220766
NOTCH1 notch 1 0.220766
PAX7 paired box 7 0.21974
CD1A CD1a molecule 0.218374
HSPA1A heat shock 70kDa protein 1A 0.214975
E2F3 E2F transcription factor 3 0.211597
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.211261
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.210253
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.208914
SDC2 syndecan 2 0.206913
NT5E 5'-nucleotidase, ecto (CD73) 0.206248
PROS2P protein S (beta) pseudogene 0.205585
CTSB cathepsin B 0.20229
ARHGAP18 Rho GTPase activating protein 18 0.201308
TSN translin 0.200006
TGFB3 transforming growth factor, beta 3 0.199356
INS insulin 0.198709
MMP19 matrix metallopeptidase 19 0.198386
CD68 CD68 molecule 0.196139
VEGFA vascular endothelial growth factor A 0.196139
CSPG4 chondroitin sulfate proteoglycan 4 0.193915
PARD6A par-6 family cell polarity regulator alpha 0.193915
FGF19 fibroblast growth factor 19 0.192971
SULF2 sulfatase 2 0.192344
IFI16 interferon, gamma-inducible protein 16 0.189859
PARVA parvin, alpha 0.188022
TIMP1 TIMP metallopeptidase inhibitor 1 0.18472
COL4A2 collagen, type IV, alpha 2 0.182375
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.181222
PRKG1 protein kinase, cGMP-dependent, type I 0.181222
CHEK2 checkpoint kinase 2 0.179239
ILK integrin-linked kinase 0.177851
VCAN versican 0.176215
PRKCZ protein kinase C, zeta 0.175679
PLAGL1 pleiomorphic adenoma gene-like 1 0.175411
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.175411
MDK midkine (neurite growth-promoting factor 2) 0.173832
BMP2 bone morphogenetic protein 2 0.173571
DAD1 defender against cell death 1 0.172799
RB1 retinoblastoma 1 0.171286
INSC inscuteable homolog (Drosophila) 0.169571
CTAG2 cancer/testis antigen 2 0.168148
NCAN neurocan 0.164359
POT1 protection of telomeres 1 0.163729
MIR96 microRNA 96 0.163111
RORA RAR-related orphan receptor A 0.162109
EZR ezrin 0.161139
ACVR2A activin A receptor, type IIA 0.160574
TGFBR3 transforming growth factor, beta receptor III 0.160021
F8 coagulation factor VIII, procoagulant component 0.159838
CORIN corin, serine peptidase 0.158434
HDAC9 histone deacetylase 9 0.158266
TES testin LIM domain protein 0.157929
FOS FBJ murine osteosarcoma viral oncogene homolog 0.157929
NKX2-2 NK2 homeobox 2 0.15537
KRT6A keratin 6A, type II 0.143947
NDRG2 NDRG family member 2 0.143784
CLCN3 chloride channel, voltage-sensitive 3 0.143754
PLAG1 pleiomorphic adenoma gene 1 0.143748
ETV1 ets variant 1 0.143446
KITLG KIT ligand 0.143407
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.142678
NAPSA napsin A aspartic peptidase 0.142474
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.141928
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.141918
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.140931
TOP2A topoisomerase (DNA) II alpha 170kDa 0.140755
NEFH neurofilament, heavy polypeptide 0.140422
CREB1 cAMP responsive element binding protein 1 0.140084
TBP TATA box binding protein 0.139647
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.139622
ACTA1 actin, alpha 1, skeletal muscle 0.139459
SOX10 SRY (sex determining region Y)-box 10 0.139412
FASN fatty acid synthase 0.139336
MKI67 marker of proliferation Ki-67 0.138889
MYH11 myosin, heavy chain 11, smooth muscle 0.136367
WT1 Wilms tumor 1 0.136205
SIK1 salt-inducible kinase 1 0.125891
VIM vimentin 0.124392
PAX3 paired box 3 0.124063
LYZ lysozyme 0.122833
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.122106
SRY sex determining region Y 0.117692
KRT20 keratin 20, type I 0.110077
ASS1 argininosuccinate synthase 1 0.109279
SCN2A sodium channel, voltage gated, type II alpha subunit 0.106645
MFGE8 milk fat globule-EGF factor 8 protein 0.105314
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.103164
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.102753
PTPRC protein tyrosine phosphatase, receptor type, C 0.10142
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.101109
NGFR nerve growth factor receptor 0.098153
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.095602
CD4 CD4 molecule 0.095346
DHFR dihydrofolate reductase 0.094354
PTH parathyroid hormone 0.093439
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.090203
GPC3 glypican 3 0.090065