chlorphenesin-7472 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the chlorphenesin-7472 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAM17 ADAM metallopeptidase domain 17
AHNAK2 AHNAK nucleoprotein 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMN amnion associated transmembrane protein
ARR3 arrestin 3, retinal (X-arrestin)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD2B ATPase family, AAA domain containing 2B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AURKA aurora kinase A
BIN1 bridging integrator 1
C17ORF80 chromosome 17 open reading frame 80
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALB2 calbindin 2
CC2D1A coiled-coil and C2 domain containing 1A
CCDC9 coiled-coil domain containing 9
CCDC93 coiled-coil domain containing 93
CD53 CD53 molecule
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNTFR ciliary neurotrophic factor receptor
COBL cordon-bleu WH2 repeat protein
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOK5 docking protein 5
DUSP13 dual specificity phosphatase 13
DUSP4 dual specificity phosphatase 4
EGFL7 EGF-like-domain, multiple 7
EVA1B eva-1 homolog B (C. elegans)
EVPL envoplakin
FANCE Fanconi anemia, complementation group E
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOXN3 forkhead box N3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GJB3 gap junction protein, beta 3, 31kDa
GPR137 G protein-coupled receptor 137
GRTP1 growth hormone regulated TBC protein 1
GSK3A glycogen synthase kinase 3 alpha
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INPP5J inositol polyphosphate-5-phosphatase J
IQCK IQ motif containing K
ITPKB inositol-trisphosphate 3-kinase B
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIAA0355 KIAA0355
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
LENEP lens epithelial protein
LHX2 LIM homeobox 2
MBD3 methyl-CpG binding domain protein 3
MED14 mediator complex subunit 14
MED16 mediator complex subunit 16
MINK1 misshapen-like kinase 1
MORN1 MORN repeat containing 1
MYL5 myosin, light chain 5, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NNAT neuronatin
NOS1 nitric oxide synthase 1 (neuronal)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PARD6B par-6 family cell polarity regulator beta
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PGAP1 post-GPI attachment to proteins 1
PLCG1 phospholipase C, gamma 1
PLCH1 phospholipase C, eta 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCE protein kinase C, epsilon
PRPF18 pre-mRNA processing factor 18
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB30 RAB30, member RAS oncogene family
RANBP3 RAN binding protein 3
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF122 ring finger protein 122
RNFT2 ring finger protein, transmembrane 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIRPA signal-regulatory protein alpha
SIRT3 sirtuin 3
SIX2 SIX homeobox 2
SLPI secretory leukocyte peptidase inhibitor
SMC1A structural maintenance of chromosomes 1A
SP140L SP140 nuclear body protein-like
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRED2 sprouty-related, EVH1 domain containing 2
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
SYNJ2 synaptojanin 2
TBC1D22A TBC1 domain family, member 22A
TBC1D5 TBC1 domain family, member 5
TRIB2 tribbles pseudokinase 2
TTC9 tetratricopeptide repeat domain 9
UPP1 uridine phosphorylase 1
UTRN utrophin
ZC3H7B zinc finger CCCH-type containing 7B
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF227 zinc finger protein 227

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASB6 ankyrin repeat and SOCS box containing 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF3 activating transcription factor 3
BBS7 Bardet-Biedl syndrome 7
BCCIP BRCA2 and CDKN1A interacting protein
C11ORF68 chromosome 11 open reading frame 68
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CHST10 carbohydrate sulfotransferase 10
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CTC1 CTS telomere maintenance complex component 1
DDIT3 DNA-damage-inducible transcript 3
DIXDC1 DIX domain containing 1
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EHD3 EH-domain containing 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHA2 EPH receptor A2
FBXL15 F-box and leucine-rich repeat protein 15
FDXR ferredoxin reductase
GCHFR GTP cyclohydrolase I feedback regulator
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP1 ganglioside induced differentiation associated protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
HIST1H2AI histone cluster 1, H2ai
HIST1H4D histone cluster 1, H4d
HIST1H4F histone cluster 1, H4f
IFT81 intraflagellar transport 81
IL17RA interleukin 17 receptor A
IRF6 interferon regulatory factor 6
KDM7A lysine (K)-specific demethylase 7A
LINC00339 long intergenic non-protein coding RNA 339
LMBR1L limb development membrane protein 1-like
LOC100287590 uncharacterized LOC100287590
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC61 leucine rich repeat containing 61
LTBP2 latent transforming growth factor beta binding protein 2
MAMLD1 mastermind-like domain containing 1
MANBA mannosidase, beta A, lysosomal
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBNL3 muscleblind-like splicing regulator 3
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MTCL1 microtubule crosslinking factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
N4BP3 NEDD4 binding protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAV2 neuron navigator 2
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
PPT2 palmitoyl-protein thioesterase 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
REPS2 RALBP1 associated Eps domain containing 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF170 ring finger protein 170
RPH3AL rabphilin 3A-like (without C2 domains)
SASH1 SAM and SH3 domain containing 1
SCHIP1 schwannomin interacting protein 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNJ2BP synaptojanin 2 binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMPRSS4 transmembrane protease, serine 4
VSIG10 V-set and immunoglobulin domain containing 10
WDR62 WD repeat domain 62
WRN Werner syndrome, RecQ helicase-like
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMAT5 zinc finger, matrin-type 5
ZNF184 zinc finger protein 184
ZNF430 zinc finger protein 430
ZNF480 zinc finger protein 480
ZNF701 zinc finger protein 701
ZNHIT2 zinc finger, HIT-type containing 2