chloropyrazine-6227 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


195 genes differentially expressed following the chloropyrazine-6227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADAM17 ADAM metallopeptidase domain 17
AOX1 aldehyde oxidase 1
ATAD5 ATPase family, AAA domain containing 5
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B9D1 B9 protein domain 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCORL1 BCL6 corepressor-like 1
C2ORF54 chromosome 2 open reading frame 54
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNO cyclin O
COL6A1 collagen, type VI, alpha 1
CORO1A coronin, actin binding protein, 1A
CREBZF CREB/ATF bZIP transcription factor
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOK2 docking protein 2, 56kDa
DXO decapping exoribonuclease
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EMID1 EMI domain containing 1
EMX1 empty spiracles homeobox 1
FLCN folliculin
FRK fyn-related Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GHRHR growth hormone releasing hormone receptor
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRK4 G protein-coupled receptor kinase 4
HBEGF heparin-binding EGF-like growth factor
HDLBP high density lipoprotein binding protein
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HSF1 heat shock transcription factor 1
ICAM1 intercellular adhesion molecule 1
IFT22 intraflagellar transport 22
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
IRF6 interferon regulatory factor 6
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JRK Jrk homolog (mouse)
KDM5A lysine (K)-specific demethylase 5A
KHK ketohexokinase (fructokinase)
KLF7 Kruppel-like factor 7 (ubiquitous)
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LIG3 ligase III, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMF2 lipase maturation factor 2
LMNA lamin A/C
LRRC14 leucine rich repeat containing 14
LYRM9 LYR motif containing 9
MAOA monoamine oxidase A
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MINK1 misshapen-like kinase 1
MOCS1 molybdenum cofactor synthesis 1
MRPS11 mitochondrial ribosomal protein S11
MST1 macrophage stimulating 1
MTRF1L mitochondrial translational release factor 1-like
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCKIPSD NCK interacting protein with SH3 domain
NEB nebulin
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPY4R neuropeptide Y receptor Y4
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAX5 paired box 5
POMT2 protein-O-mannosyltransferase 2
PTGER3 prostaglandin E receptor 3 (subtype EP3)
QKI QKI, KH domain containing, RNA binding
RAB27B RAB27B, member RAS oncogene family
RREB1 ras responsive element binding protein 1
RTN2 reticulon 2
SBNO2 strawberry notch homolog 2 (Drosophila)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETBP1 SET binding protein 1
SFXN3 sideroflexin 3
SGSM2 small G protein signaling modulator 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
STRA6 stimulated by retinoic acid 6
STYK1 serine/threonine/tyrosine kinase 1
SUGP1 SURP and G patch domain containing 1
TAGLN3 transgelin 3
TOR1AIP1 torsin A interacting protein 1
TRD T cell receptor delta locus
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC23 tetratricopeptide repeat domain 23
ULBP2 UL16 binding protein 2
WDR59 WD repeat domain 59
WWTR1 WW domain containing transcription regulator 1
YY1 YY1 transcription factor
ZFPL1 zinc finger protein-like 1
ZNF318 zinc finger protein 318
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD36 ankyrin repeat domain 36
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BAGE B melanoma antigen
BAX BCL2-associated X protein
C5ORF45 chromosome 5 open reading frame 45
CDK3 cyclin-dependent kinase 3
CDK9 cyclin-dependent kinase 9
CFD complement factor D (adipsin)
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRABP1 cellular retinoic acid binding protein 1
CUEDC1 CUE domain containing 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAF1 DEAF1 transcription factor
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DOLPP1 dolichyldiphosphatase 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ERCC4 excision repair cross-complementation group 4
FAM118A family with sequence similarity 118, member A
FBXO22 F-box protein 22
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB2 GRB2-associated binding protein 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
HIST1H2AM histone cluster 1, H2am
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
HTRA1 HtrA serine peptidase 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IP6K1 inositol hexakisphosphate kinase 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIF20A kinesin family member 20A
KRBOX4 KRAB box domain containing 4
KRT8P12 keratin 8 pseudogene 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MNS1 meiosis-specific nuclear structural 1
MPI mannose phosphate isomerase
MRPL2 mitochondrial ribosomal protein L2
MXD3 MAX dimerization protein 3
NES nestin
ONECUT2 one cut homeobox 2
PARP16 poly (ADP-ribose) polymerase family, member 16
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTPRU protein tyrosine phosphatase, receptor type, U
PUS3 pseudouridylate synthase 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL4 RecQ protein-like 4
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SH2D4A SH2 domain containing 4A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI2 snail family zinc finger 2
SNX16 sorting nexin 16
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
STX5 syntaxin 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT17 synaptotagmin XVII
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPST1 tyrosylprotein sulfotransferase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN5 tetraspanin 5
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBXN6 UBX domain protein 6
VAV1 vav 1 guanine nucleotide exchange factor
VWA1 von Willebrand factor A domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMYM3 zinc finger, MYM-type 3
ZNF141 zinc finger protein 141
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF669 zinc finger protein 669