chlorogenic acid-4024 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the chlorogenic acid-4024 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACVR1B activin A receptor, type IB
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANP32A-IT1 ANP32A intronic transcript 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLP2 amyloid beta (A4) precursor-like protein 2
ATAT1 alpha tubulin acetyltransferase 1
ATP9B ATPase, class II, type 9B
BEND5 BEN domain containing 5
CCDC132 coiled-coil domain containing 132
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CFLAR CASP8 and FADD-like apoptosis regulator
CHM choroideremia (Rab escort protein 1)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLTCL1 clathrin, heavy chain-like 1
COL3A1 collagen, type III, alpha 1
COL4A6 collagen, type IV, alpha 6
CRTC1 CREB regulated transcription coactivator 1
CST1 cystatin SN
CST4 cystatin S
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGKE diacylglycerol kinase, epsilon 64kDa
EBF2 early B-cell factor 2
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EML2 echinoderm microtubule associated protein like 2
EPHA5 EPH receptor A5
ERAP1 endoplasmic reticulum aminopeptidase 1
ETV1 ets variant 1
FAM63A family with sequence similarity 63, member A
FN1 fibronectin 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GTDC1 glycosyltransferase-like domain containing 1
HEG1 heart development protein with EGF-like domains 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIPK3 homeodomain interacting protein kinase 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL15 interleukin 15
INO80D INO80 complex subunit D
KAT5 K(lysine) acetyltransferase 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA1109 KIAA1109
LDHC lactate dehydrogenase C
LGALS8 lectin, galactoside-binding, soluble, 8
LIMCH1 LIM and calponin homology domains 1
MME membrane metallo-endopeptidase
MORC2 MORC family CW-type zinc finger 2
NPY neuropeptide Y
OAZ3 ornithine decarboxylase antizyme 3
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PACRG PARK2 co-regulated
PDE11A phosphodiesterase 11A
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PITX2 paired-like homeodomain 2
PLN phospholamban
PLXDC1 plexin domain containing 1
PLXNA2 plexin A2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTPRR protein tyrosine phosphatase, receptor type, R
RHAG Rh-associated glycoprotein
RHOBTB3 Rho-related BTB domain containing 3
RIBC2 RIB43A domain with coiled-coils 2
RIOK3 RIO kinase 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RYK receptor-like tyrosine kinase
S1PR1 sphingosine-1-phosphate receptor 1
SAFB scaffold attachment factor B
SDF4 stromal cell derived factor 4
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOS2 son of sevenless homolog 2 (Drosophila)
SPRYD7 SPRY domain containing 7
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
THBD thrombomodulin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
TTC12 tetratricopeptide repeat domain 12
TTC30A tetratricopeptide repeat domain 30A
VAMP4 vesicle-associated membrane protein 4
VGF VGF nerve growth factor inducible
VIPR2 vasoactive intestinal peptide receptor 2
VNN1 vanin 1
ZBTB18 zinc finger and BTB domain containing 18
ZNF573 zinc finger protein 573
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACBD4 acyl-CoA binding domain containing 4
ACTA1 actin, alpha 1, skeletal muscle
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12 arachidonate 12-lipoxygenase
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALOX15B arachidonate 15-lipoxygenase, type B
ARHGAP22 Rho GTPase activating protein 22
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BST1 bone marrow stromal cell antigen 1
C14ORF93 chromosome 14 open reading frame 93
C7ORF69 chromosome 7 open reading frame 69
CA9 carbonic anhydrase IX
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CGA glycoprotein hormones, alpha polypeptide
CHI3L2 chitinase 3-like 2
CLDN17 claudin 17
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
DNAH7 dynein, axonemal, heavy chain 7
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNB1 ephrin-B1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FKBP10 FK506 binding protein 10, 65 kDa
FRMPD1 FERM and PDZ domain containing 1
FSD1 fibronectin type III and SPRY domain containing 1
GCHFR GTP cyclohydrolase I feedback regulator
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GREB1L growth regulation by estrogen in breast cancer-like
GRM4 glutamate receptor, metabotropic 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HDAC7 histone deacetylase 7
HHAT hedgehog acyltransferase
HIST1H3I histone cluster 1, H3i
HOXC4 homeobox C4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGLL1 immunoglobulin lambda-like polypeptide 1
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCTD17 potassium channel tetramerization domain containing 17
KRT31 keratin 31, type I
LINC00472 long intergenic non-protein coding RNA 472
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAP3K7CL MAP3K7 C-terminal like
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMP10 matrix metallopeptidase 10
MYL5 myosin, light chain 5, regulatory
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDRG4 NDRG family member 4
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NOTCH4 notch 4
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
PAIP2B poly(A) binding protein interacting protein 2B
PAQR5 progestin and adipoQ receptor family member V
PAX9 paired box 9
PIP prolactin-induced protein
PLAG1 pleiomorphic adenoma gene 1
PLD3 phospholipase D family, member 3
POLL polymerase (DNA directed), lambda
PSORS1C1 psoriasis susceptibility 1 candidate 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN10A sodium channel, voltage gated, type X alpha subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLN sarcolipin
SMR3A submaxillary gland androgen regulated protein 3A
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
WFDC2 WAP four-disulfide core domain 2
ZNF280A zinc finger protein 280A
ZNF358 zinc finger protein 358
ZNF528 zinc finger protein 528
ZNF747 zinc finger protein 747
ZXDB zinc finger, X-linked, duplicated B