chemokine receptor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. (Gene Ontology, GO_0004950)
External Link http://amigo.geneontology.org/amigo/term/GO:0004950
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Genes

26 genes performing the chemokine receptor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
CCR1 chemokine (C-C motif) receptor 1
CCR10 chemokine (C-C motif) receptor 10
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CCR9 chemokine (C-C motif) receptor 9
CCRL2 chemokine (C-C motif) receptor-like 2
CMKLR1 chemerin chemokine-like receptor 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CXCR6 chemokine (C-X-C motif) receptor 6
GPR17 G protein-coupled receptor 17
GPR75 G protein-coupled receptor 75
RGR retinal G protein coupled receptor
XCR1 chemokine (C motif) receptor 1