checkpoint Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

206 proteins co-occuring with the biological term checkpoint in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
APLF aprataxin and PNKP like factor
ARFIP1 ADP-ribosylation factor interacting protein 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
AURKA aurora kinase A
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BORA bora, aurora kinase A activator
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDCA2 cell division cycle associated 2
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPA centromere protein A
CENPT centromere protein T
CENPU centromere protein U
CEP164 centrosomal protein 164kDa
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHMP4C charged multivesicular body protein 4C
CLASP2 cytoplasmic linker associated protein 2
CLSPN claspin
CREB1 cAMP responsive element binding protein 1
CSNK2B casein kinase 2, beta polypeptide
CUEDC2 CUE domain containing 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBF4 DBF4 zinc finger
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DCTN6 dynactin 6
DVL2 dishevelled segment polarity protein 2
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EXO1 exonuclease 1
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCM Fanconi anemia, complementation group M
FHIT fragile histidine triad
FOXM1 forkhead box M1
FOXO1 forkhead box O1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTSE1 G-2 and S-phase expressed 1
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HIST1H2AI histone cluster 1, H2ai
HIST1H3A histone cluster 1, H3a
HORMAD1 HORMA domain containing 1
HORMAD2 HORMA domain containing 2
HSF1 heat shock transcription factor 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
INCENP inner centromere protein antigens 135/155kDa
ING1 inhibitor of growth family, member 1
IRF3 interferon regulatory factor 3
JAK1 Janus kinase 1
JUN jun proto-oncogene
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KMT2A lysine (K)-specific methyltransferase 2A
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP9 microtubule-associated protein 9
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MCC mutated in colorectal cancers
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM7 minichromosome maintenance complex component 7
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLH1 mutL homolog 1
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MYL9 myosin, light chain 9, regulatory
MYOD1 myogenic differentiation 1
NABP2 nucleic acid binding protein 2
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NDC80 NDC80 kinetochore complex component
NDEL1 nudE neurodevelopment protein 1-like 1
NEK11 NIMA-related kinase 11
NUSAP1 nucleolar and spindle associated protein 1
ORC2 origin recognition complex, subunit 2
PARN poly(A)-specific ribonuclease
PCBP1 poly(rC) binding protein 1
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLK1 polo-like kinase 1
PML promyelocytic leukemia
POLH polymerase (DNA directed), eta
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RPA2 replication protein A2, 32kDa
RPL13A ribosomal protein L13a
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
SGOL1 shugoshin-like 1 (S. pombe)
SMAD2 SMAD family member 2
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIP1 stress-induced phosphoprotein 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SYK spleen tyrosine kinase
TACC3 transforming, acidic coiled-coil containing protein 3
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEX14 testis expressed 14
TICRR TOPBP1-interacting checkpoint and replication regulator
TLK1 tousled-like kinase 1
TLX1 T-cell leukemia homeobox 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TRIM28 tripartite motif containing 28
TTK TTK protein kinase
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WEE1 WEE1 G2 checkpoint kinase
XPA xeroderma pigmentosum, complementation group A
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YBX1 Y box binding protein 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZWINT ZW10 interacting kinetochore protein