chamber of the eye Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description One of he various spaces in the eyeball. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002085)
Similar Terms
Downloads & Tools

Genes

410 proteins co-occuring with the tissue chamber of the eye in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TGFB2 transforming growth factor, beta 2 1.57013
OPTC opticin 1.48364
FGF7 fibroblast growth factor 7 1.33364
TGFB1 transforming growth factor, beta 1 1.22559
FGF10 fibroblast growth factor 10 1.22291
TTR transthyretin 1.14609
TF transferrin 1.13324
FGFR2 fibroblast growth factor receptor 2 1.08855
VEGFA vascular endothelial growth factor A 1.08678
ALB albumin 1.07221
FGF1 fibroblast growth factor 1 (acidic) 1.02162
FOXF1 forkhead box F1 1.00109
SAG S-antigen; retina and pineal gland (arrestin) 0.998037
CRYGS crystallin, gamma S 0.981518
FGF2 fibroblast growth factor 2 (basic) 0.955996
SLC12A8 solute carrier family 12, member 8 0.932766
GDNF glial cell derived neurotrophic factor 0.919061
PLAT plasminogen activator, tissue 0.915642
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.908814
NDP Norrie disease (pseudoglioma) 0.868107
IL6 interleukin 6 0.865155
IGF1 insulin-like growth factor 1 (somatomedin C) 0.857995
COL2A1 collagen, type II, alpha 1 0.846225
SAP30L SAP30-like 0.842867
RBP3 retinol binding protein 3, interstitial 0.831129
CRYAA crystallin, alpha A 0.826523
CCL2 chemokine (C-C motif) ligand 2 0.798125
CPNE6 copine VI (neuronal) 0.77774
FN1 fibronectin 1 0.774834
MET MET proto-oncogene, receptor tyrosine kinase 0.774004
INS insulin 0.7595
RSPO4 R-spondin 4 0.755777
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.742976
CNTF ciliary neurotrophic factor 0.742976
WT1 Wilms tumor 1 0.726918
DPYSL5 dihydropyrimidinase-like 5 0.705173
CNTN2 contactin 2 (axonal) 0.703945
TH tyrosine hydroxylase 0.702308
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.676172
HVCN1 hydrogen voltage gated channel 1 0.672506
NGF nerve growth factor (beta polypeptide) 0.667622
PLAU plasminogen activator, urokinase 0.665182
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.661116
NARF nuclear prelamin A recognition factor 0.659897
PLG plasminogen 0.655024
CD4 CD4 molecule 0.6534
FOXC1 forkhead box C1 0.646505
AMHR2 anti-Mullerian hormone receptor, type II 0.644479
HOXA5 homeobox A5 0.642454
BDNF brain-derived neurotrophic factor 0.63638
ICAM1 intercellular adhesion molecule 1 0.63274
CTSA cathepsin A 0.614974
ACE angiotensin I converting enzyme 0.612958
ZC3H13 zinc finger CCCH-type containing 13 0.60893
NKX2-1 NK2 homeobox 1 0.607722
AQP4 aquaporin 4 0.606112
PAX6 paired box 6 0.605709
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.594451
CRYBB2 crystallin, beta B2 0.592845
FGF9 fibroblast growth factor 9 0.586828
SOD3 superoxide dismutase 3, extracellular 0.580818
SRCIN1 SRC kinase signaling inhibitor 1 0.575216
AR androgen receptor 0.569222
BCAP29 B-cell receptor-associated protein 29 0.564035
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.562441
PAX2 paired box 2 0.56005
COL11A1 collagen, type XI, alpha 1 0.550503
CXCL8 chemokine (C-X-C motif) ligand 8 0.550503
SAP30 Sin3A-associated protein, 30kDa 0.543756
AFM afamin 0.539793
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.539
PPT1 palmitoyl-protein thioesterase 1 0.531879
LYPLAL1 lysophospholipase-like 1 0.529903
SLC38A1 solute carrier family 38, member 1 0.524771
FASLG Fas ligand (TNF superfamily, member 6) 0.523982
MIR211 microRNA 211 0.5228
POU4F1 POU class 4 homeobox 1 0.522011
ADM adrenomedullin 0.521223
OTOR otoraplin 0.520041
C4A complement component 4A (Rodgers blood group) 0.516891
PI15 peptidase inhibitor 15 0.51453
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.512564
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.502357
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.493745
BMP4 bone morphogenetic protein 4 0.492963
IPO5 importin 5 0.492963
SARM1 sterile alpha and TIR motif containing 1 0.492182
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.490229
COL18A1 collagen, type XVIII, alpha 1 0.487886
EDN1 endothelin 1 0.487106
SOD2 superoxide dismutase 2, mitochondrial 0.485935
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.476979
IGFBP3 insulin-like growth factor binding protein 3 0.472704
EDA ectodysplasin A 0.468824
CLDN12 claudin 12 0.462239
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.459532
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.458373
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.454898
FZD4 frizzled class receptor 4 0.449116
SHH sonic hedgehog 0.445653
CHD7 chromodomain helicase DNA binding protein 7 0.444115
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.441426
RPE65 retinal pigment epithelium-specific protein 65kDa 0.43989
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.437205
RCVRN recoverin 0.434523
NDE1 nudE neurodevelopment protein 1 0.432991
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.43146
MMP2 matrix metallopeptidase 2 0.430695
GPANK1 G patch domain and ankyrin repeats 1 0.428783
TGIF1 TGFB-induced factor homeobox 1 0.427254
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.423054
TGFB3 transforming growth factor, beta 3 0.420766
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.417718
CAPN5 calpain 5 0.417337
EPYC epiphycan 0.41087
DSE dermatan sulfate epimerase 0.410491
TNF tumor necrosis factor 0.410491
MIR184 microRNA 184 0.409731
TSPO translocator protein (18kDa) 0.408592
CP ceruloplasmin (ferroxidase) 0.405935
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.40366
TBX22 T-box 22 0.40025
IL10 interleukin 10 0.40025
AGK acylglycerol kinase 0.40025
HLA-B major histocompatibility complex, class I, B 0.398357
CAT catalase 0.396465
CASS4 Cas scaffolding protein family member 4 0.396465
KREMEN1 kringle containing transmembrane protein 1 0.395709
CD79A CD79a molecule, immunoglobulin-associated alpha 0.389666
COL9A3 collagen, type IX, alpha 3 0.388158
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.385896
TNC tenascin C 0.385143
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.384766
NID1 nidogen 1 0.382131
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.380251
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.380251
MIP major intrinsic protein of lens fiber 0.376494
IRX4 iroquois homeobox 4 0.374993
IL1B interleukin 1, beta 0.371994
BMP7 bone morphogenetic protein 7 0.371619
HMGB1 high mobility group box 1 0.368998
IL1A interleukin 1, alpha 0.361901
RARS arginyl-tRNA synthetase 0.361155
MERTK MER proto-oncogene, tyrosine kinase 0.360782
ATL2 atlastin GTPase 2 0.357802
EPO erythropoietin 0.352969
EPOR erythropoietin receptor 0.352227
NDN necdin, melanoma antigen (MAGE) family member 0.352227
MSX1 msh homeobox 1 0.351856
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.350743
CD44 CD44 molecule (Indian blood group) 0.347778
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.335968
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.335968
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.3356
PTPRK protein tyrosine phosphatase, receptor type, K 0.334865
THY1 Thy-1 cell surface antigen 0.331927
ERBB4 erb-b2 receptor tyrosine kinase 4 0.330094
GLB1 galactosidase, beta 1 0.328262
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.327896
PITX3 paired-like homeodomain 3 0.327164
CALB2 calbindin 2 0.326432
PRPH2 peripherin 2 (retinal degeneration, slow) 0.325701
FOXL1 forkhead box L1 0.324239
KLK1 kallikrein 1 0.322779
TIMP1 TIMP metallopeptidase inhibitor 1 0.322779
CTGF connective tissue growth factor 0.320591
CRYBB1 crystallin, beta B1 0.319863
FABP3 fatty acid binding protein 3, muscle and heart 0.317679
NKX3-1 NK3 homeobox 1 0.316951
ACHE acetylcholinesterase (Yt blood group) 0.310421
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.309697
PLCH2 phospholipase C, eta 2 0.307528
TAC1 tachykinin, precursor 1 0.305361
SOSTDC1 sclerostin domain containing 1 0.305001
CD68 CD68 molecule 0.30464
NEUROD4 neuronal differentiation 4 0.303919
GLUL glutamate-ammonia ligase 0.300679
RAB3D RAB3D, member RAS oncogene family 0.30032
BCAN brevican 0.294939
HTRA3 HtrA serine peptidase 3 0.293151
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.292436
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 0.291365
MITF microphthalmia-associated transcription factor 0.289939
WNT10B wingless-type MMTV integration site family, member 10B 0.289582
DCN decorin 0.286381
SFRP2 secreted frizzled-related protein 2 0.284962
THBS1 thrombospondin 1 0.283899
STRA6 stimulated by retinoic acid 6 0.281776
ERBB3 erb-b2 receptor tyrosine kinase 3 0.279659
SHOX2 short stature homeobox 2 0.278955
HLX H2.0-like homeobox 0.275794
COL8A2 collagen, type VIII, alpha 2 0.274394
SST somatostatin 0.274394
SMAD2 SMAD family member 2 0.270561
OCLN occludin 0.270214
SLC38A4 solute carrier family 38, member 4 0.269174
OFD1 oral-facial-digital syndrome 1 0.268482
TGM5 transglutaminase 5 0.266413
OSR2 odd-skipped related transciption factor 2 0.266069
SHBG sex hormone-binding globulin 0.266069
RS1 retinoschisin 1 0.261284
FGFR1 fibroblast growth factor receptor 1 0.258917
PXDN peroxidasin 0.257907
KDR kinase insert domain receptor 0.257907
IRX1 iroquois homeobox 1 0.253248
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 0.249977
TJP1 tight junction protein 1 0.248683
HAS2 hyaluronan synthase 2 0.245926
SDC2 syndecan 2 0.239007
NTF3 neurotrophin 3 0.238406
DPT dermatopontin 0.23781
COL11A2 collagen, type XI, alpha 2 0.237216
NPY neuropeptide Y 0.23604
GJA3 gap junction protein, alpha 3, 46kDa 0.234878
CCL3 chemokine (C-C motif) ligand 3 0.231482
TECR trans-2,3-enoyl-CoA reductase 0.229839
TEF thyrotrophic embryonic factor 0.228764
CMA1 chymase 1, mast cell 0.228234
NLRP1 NLR family, pyrin domain containing 1 0.227186
BCHE butyrylcholinesterase 0.227186
REN renin 0.226926
BFSP2 beaded filament structural protein 2, phakinin 0.223662
FGFBP1 fibroblast growth factor binding protein 1 0.223177
CLDN18 claudin 18 0.221291
MIRLET7C microRNA let-7c 0.221291
ONECUT1 one cut homeobox 1 0.219485
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.219047
TBX4 T-box 4 0.218613
ACTB actin, beta 0.218398
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.217974
LTBP3 latent transforming growth factor beta binding protein 3 0.217554
HOXD11 homeobox D11 0.21673
WDR11 WD repeat domain 11 0.215928
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.215534
GJB6 gap junction protein, beta 6, 30kDa 0.215534
GJA8 gap junction protein, alpha 8, 50kDa 0.214202
TPR translocated promoter region, nuclear basket protein 0.213291
FLT1 fms-related tyrosine kinase 1 0.213112
PITX2 paired-like homeodomain 2 0.212761
ELSPBP1 epididymal sperm binding protein 1 0.212761
HAS3 hyaluronan synthase 3 0.195873
RBBP9 retinoblastoma binding protein 9 0.194583
COL1A1 collagen, type I, alpha 1 0.188723
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.187219
PDGFB platelet-derived growth factor beta polypeptide 0.187128
RGN regucalcin 0.182251
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.178706
ANGPTL6 angiopoietin-like 6 0.177958
AADAT aminoadipate aminotransferase 0.177849
VIT vitrin 0.177603
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.177575
MGAM maltase-glucoamylase 0.177575
DTNA dystrobrevin, alpha 0.177547
HGD homogentisate 1,2-dioxygenase 0.177296
MIR214 microRNA 214 0.177268
GSAP gamma-secretase activating protein 0.177068
RHCE Rh blood group, CcEe antigens 0.176838
CXCL10 chemokine (C-X-C motif) ligand 10 0.176691
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.175891
STK38 serine/threonine kinase 38 0.175563
BTG3 BTG family, member 3 0.175531
NTN1 netrin 1 0.175467
NOG noggin 0.175339
HLA-DMA major histocompatibility complex, class II, DM alpha 0.175243
TIMP2 TIMP metallopeptidase inhibitor 2 0.175211
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.17508
MIRLET7B microRNA let-7b 0.174883
IL6R interleukin 6 receptor 0.174883
HPX hemopexin 0.17485
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.174651
RHOD ras homolog family member D 0.174583
GYPC glycophorin C (Gerbich blood group) 0.174174
CNTN6 contactin 6 0.174139
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.174034
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.17393
POU3F4 POU class 3 homeobox 4 0.173719
ZC3H12D zinc finger CCCH-type containing 12D 0.173683
LECT1 leukocyte cell derived chemotaxin 1 0.173396
APOH apolipoprotein H (beta-2-glycoprotein I) 0.17336
MASP2 mannan-binding lectin serine peptidase 2 0.173288
KIN Kin17 DNA and RNA binding protein 0.173104
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.17258
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.172542
OSGEP O-sialoglycoprotein endopeptidase 0.171962
RLBP1 retinaldehyde binding protein 1 0.171707
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.171606
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.171606
VCAN versican 0.171322
HYAL2 hyaluronoglucosaminidase 2 0.171322
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.169574
RHD Rh blood group, D antigen 0.16926
LTBP2 latent transforming growth factor beta binding protein 2 0.169031
CDK11A cyclin-dependent kinase 11A 0.168847
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.16716
CTSC cathepsin C 0.167134
CAPN1 calpain 1, (mu/I) large subunit 0.165736
FAM195A family with sequence similarity 195, member A 0.164474
VSX1 visual system homeobox 1 0.163021
BAG3 BCL2-associated athanogene 3 0.162079
PTRF polymerase I and transcript release factor 0.162079
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.161673
COL4A2 collagen, type IV, alpha 2 0.161673
IRX3 iroquois homeobox 3 0.161357
CLDN6 claudin 6 0.160747
HMX2 H6 family homeobox 2 0.16042
IHH indian hedgehog 0.16042
AHR aryl hydrocarbon receptor 0.159856
ACTG1 actin gamma 1 0.159485
BOC BOC cell adhesion associated, oncogene regulated 0.159181
E2F5 E2F transcription factor 5, p130-binding 0.159147
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.159077
SULF1 sulfatase 1 0.159007
HOXA11 homeobox A11 0.158972
HLA-E major histocompatibility complex, class I, E 0.158903
TBX18 T-box 18 0.158206
FBLN1 fibulin 1 0.158027
AMH anti-Mullerian hormone 0.157416
COL4A1 collagen, type IV, alpha 1 0.156866
FBLN2 fibulin 2 0.156533
SFTPC surfactant protein C 0.156533
MSX2 msh homeobox 2 0.156348
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.155932
BMP5 bone morphogenetic protein 5 0.15555
KIF3A kinesin family member 3A 0.154972
HDC histidine decarboxylase 0.154618
GC group-specific component (vitamin D binding protein) 0.154421
CLU clusterin 0.154342
EML4 echinoderm microtubule associated protein like 4 0.153986
PRDM2 PR domain containing 2, with ZNF domain 0.153783
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.153539
MEOX2 mesenchyme homeobox 2 0.153377
SALL1 spalt-like transcription factor 1 0.152638
KLK3 kallikrein-related peptidase 3 0.152304
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.152095
KRT9 keratin 9, type I 0.151717
SPRY2 sprouty homolog 2 (Drosophila) 0.151631
FLCN folliculin 0.151287
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.15051
PNMT phenylethanolamine N-methyltransferase 0.150244
CTBS chitobiase, di-N-acetyl- 0.1502
TRIM37 tripartite motif containing 37 0.149934
WNT2B wingless-type MMTV integration site family, member 2B 0.148948
PAX4 paired box 4 0.147988
FGF4 fibroblast growth factor 4 0.147003
TBX2 T-box 2 0.146956
HOXB7 homeobox B7 0.146575
JUNB jun B proto-oncogene 0.1459
FOXJ1 forkhead box J1 0.145369
EXT1 exostosin glycosyltransferase 1 0.145022
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.144823
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.144229
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.143929
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.143878
E2F3 E2F transcription factor 3 0.142708
PRF1 perforin 1 (pore forming protein) 0.142397
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.142083
TBX1 T-box 1 0.142083
WNT7B wingless-type MMTV integration site family, member 7B 0.141353
PTCH1 patched 1 0.139751
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.139148
CYCS cytochrome c, somatic 0.138764
ACAN aggrecan 0.138435
ACVR2A activin A receptor, type IIA 0.138048
MNX1 motor neuron and pancreas homeobox 1 0.137879
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.137711
WNT11 wingless-type MMTV integration site family, member 11 0.136471
CHAT choline O-acetyltransferase 0.136241
EREG epiregulin 0.136068
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.135953
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.135838
CD163 CD163 molecule 0.135838
CRABP2 cellular retinoic acid binding protein 2 0.135723
AIF1 allograft inflammatory factor 1 0.135723
JUN jun proto-oncogene 0.135034
FGF3 fibroblast growth factor 3 0.134798
KRT16 keratin 16, type I 0.134386
PBX1 pre-B-cell leukemia homeobox 1 0.133445
IVL involucrin 0.133326
TST thiosulfate sulfurtransferase (rhodanese) 0.133266
DES desmin 0.132965
ALCAM activated leukocyte cell adhesion molecule 0.132604
BSN bassoon presynaptic cytomatrix protein 0.132423
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.132063
GFAP glial fibrillary acidic protein 0.131517
WNT2 wingless-type MMTV integration site family member 2 0.131026
CALCA calcitonin-related polypeptide alpha 0.13078
E2F4 E2F transcription factor 4, p107/p130-binding 0.130657
SMAD4 SMAD family member 4 0.129793
NOTCH1 notch 1 0.129417
KITLG KIT ligand 0.128916
OPN4 opsin 4 0.128916
CLDN11 claudin 11 0.12879
PTER phosphotriesterase related 0.12829
PTHLH parathyroid hormone-like hormone 0.127714
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.127714
TBX5 T-box 5 0.127075
ICAM2 intercellular adhesion molecule 2 0.126692
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.126564
LAMA3 laminin, alpha 3 0.126043
CLDN5 claudin 5 0.125717
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.125457
MGST1 microsomal glutathione S-transferase 1 0.125327
S100G S100 calcium binding protein G 0.125197
COL7A1 collagen, type VII, alpha 1 0.125132
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 0.124807
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.124676
BMPR1B bone morphogenetic protein receptor, type IB 0.124609
POLL polymerase (DNA directed), lambda 0.124543
HIST2H2BF histone cluster 2, H2bf 0.124211
HIST3H2BB histone cluster 3, H2bb 0.124211