chains Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

311 genes co-occuring with the biological term chains in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADRM1 adhesion regulating molecule 1
AGFG1 ArfGAP with FG repeats 1
AHSP alpha hemoglobin stabilizing protein
AMBP alpha-1-microglobulin/bikunin precursor
AMBRA1 autophagy/beclin-1 regulator 1
AMD1 adenosylmethionine decarboxylase 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA2 annexin A2
ANXA6 annexin A6
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATRIP ATR interacting protein
ATXN3 ataxin 3
AURKB aurora kinase B
B2M beta-2-microglobulin
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
BARD1 BRCA1 associated RING domain 1
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BGN biglycan
BIN1 bridging integrator 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BRAT1 BRCA1-associated ATM activator 1
BRCA1 breast cancer 1, early onset
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
CA2 carbonic anhydrase II
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CANX calnexin
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CD14 CD14 molecule
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CD79A CD79a molecule, immunoglobulin-associated alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRM3 cholinergic receptor, muscarinic 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHSY1 chondroitin sulfate synthase 1
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CNR2 cannabinoid receptor 2 (macrophage)
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A4P1 collagen, type VI, alpha 4 pseudogene 1
COL6A4P2 collagen, type VI, alpha 4 pseudogene 2
COL6A5 collagen, type VI, alpha 5
COL6A6 collagen, type VI, alpha 6
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CRYAB crystallin, alpha B
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSK c-src tyrosine kinase
CXCL12 chemokine (C-X-C motif) ligand 12
CYLD cylindromatosis (turban tumor syndrome)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCN decorin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DERL1 derlin 1
DGKE diacylglycerol kinase, epsilon 64kDa
DMBT1 deleted in malignant brain tumors 1
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNASE1 deoxyribonuclease I
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
EXT2 exostosin glycosyltransferase 2
F10 coagulation factor X
F11 coagulation factor XI
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FAS Fas cell surface death receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FECH ferrochelatase
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF18 fibroblast growth factor 18
FGF2 fibroblast growth factor 2 (basic)
FGFR1OP FGFR1 oncogene partner
FGG fibrinogen gamma chain
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCK glucokinase (hexokinase 4)
GLRA1 glycine receptor, alpha 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC1 glypican 1
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
H2AFX H2A histone family, member X
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HAS3 hyaluronan synthase 3
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBG2 hemoglobin, gamma G
HEXB hexosaminidase B (beta polypeptide)
HIST2H2AA3 histone cluster 2, H2aa3
HIST2H2AC histone cluster 2, H2ac
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HPRT1 hypoxanthine phosphoribosyltransferase 1
HPSE heparanase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPG2 heparan sulfate proteoglycan 2
IFNB1 interferon, beta 1, fibroblast
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGH immunoglobulin heavy locus
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHM immunoglobulin heavy constant mu
IGK immunoglobulin kappa locus
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IGLV@ immunoglobulin lambda variable cluster
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL18R1 interleukin 18 receptor 1
IL2 interleukin 2
IL22 interleukin 22
IL22RA1 interleukin 22 receptor, alpha 1
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3 interleukin 3
IL5RA interleukin 5 receptor, alpha
INS insulin
INSR insulin receptor
IRF3 interferon regulatory factor 3
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
LACRT lacritin
LALBA lactalbumin, alpha-
LAMA1 laminin, alpha 1
LAMA3 laminin, alpha 3
LAMA4 laminin, alpha 4
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMB3 laminin, beta 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
LAMC3 laminin, gamma 3
LEF1 lymphoid enhancer-binding factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMAN1 lectin, mannose-binding, 1
LMX1B LIM homeobox transcription factor 1, beta
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP1 low density lipoprotein receptor-related protein 1
LUM lumican
LY96 lymphocyte antigen 96
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MEP1B meprin A, beta
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MVK mevalonate kinase
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK myosin light chain kinase
NBR1 neighbor of BRCA1 gene 1
NCAM1 neural cell adhesion molecule 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
P3H2 prolyl 3-hydroxylase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD6IP programmed cell death 6 interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PDPN podoplanin
PEBP1 phosphatidylethanolamine binding protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLG plasminogen
PLTP phospholipid transfer protein
POLH polymerase (DNA directed), eta
POLI polymerase (DNA directed) iota
PPARG peroxisome proliferator-activated receptor gamma
PRKCE protein kinase C, epsilon
PRLR prolactin receptor
PRMT1 protein arginine methyltransferase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTX3 pentraxin 3, long
RAB21 RAB21, member RAS oncogene family
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RNF4 ring finger protein 4
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
S100A10 S100 calcium binding protein A10
SDC1 syndecan 1
SDC4 syndecan 4
SDCBP syndecan binding protein (syntenin)
SENP6 SUMO1/sentrin specific peptidase 6
SFTPD surfactant protein D
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPN sialophorin
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBK1 TANK-binding kinase 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR4 toll-like receptor 4
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMPRSS15 transmembrane protease, serine 15
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRA T cell receptor alpha locus
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRB T cell receptor beta locus
TRIM14 tripartite motif containing 14
TRIM32 tripartite motif containing 32
TRIM6 tripartite motif containing 6
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTR transthyretin
UBB ubiquitin B
UBC ubiquitin C
UBD ubiquitin D
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2N ubiquitin-conjugating enzyme E2N
UBE2S ubiquitin-conjugating enzyme E2S
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN1 UBX domain protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UIMC1 ubiquitin interaction motif containing 1
USP10 ubiquitin specific peptidase 10
USP15 ubiquitin specific peptidase 15
USP2 ubiquitin specific peptidase 2
USP25 ubiquitin specific peptidase 25
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCAN versican
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VIMP VCP-interacting membrane selenoprotein
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1
XAGE1B X antigen family, member 1B
XBP1 X-box binding protein 1
ZNF593 zinc finger protein 593