cerebral white matter Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Whitish nerve tissue, especially of the brain and spinal cord, consisting chiefly of myelinated nerve fibers. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000236)
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Genes

745 proteins co-occuring with the tissue cerebral white matter in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MBP myelin basic protein 2.87153
NOTCH3 notch 3 2.28651
NOTCH4 notch 4 2.20771
GFAP glial fibrillary acidic protein 2.1998
LAMA2 laminin, alpha 2 2.17712
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.06638
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 2.04819
PLP1 proteolipid protein 1 1.95619
APOE apolipoprotein E 1.90239
OLIG2 oligodendrocyte lineage transcription factor 2 1.87133
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.86668
MAG myelin associated glycoprotein 1.83272
ASPA aspartoacylase 1.81992
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.80972
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.80921
MOG myelin oligodendrocyte glycoprotein 1.76676
MAPT microtubule-associated protein tau 1.68503
GALC galactosylceramidase 1.68005
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.65107
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.63556
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.57699
RICTOR RPTOR independent companion of MTOR, complex 2 1.56476
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.55649
FABP3 fatty acid binding protein 3, muscle and heart 1.54632
SPG11 spastic paraplegia 11 (autosomal recessive) 1.5367
ARSA arylsulfatase A 1.50858
MAP2 microtubule-associated protein 2 1.50575
AIF1 allograft inflammatory factor 1 1.48786
SYP synaptophysin 1.46728
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.46262
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 1.4575
AQP4 aquaporin 4 1.44126
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.40386
APP amyloid beta (A4) precursor protein 1.39238
BDNF brain-derived neurotrophic factor 1.3791
FKTN fukutin 1.35995
CD68 CD68 molecule 1.33184
NES nestin 1.32867
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.3219
TRIM65 tripartite motif containing 65 1.3192
CALB1 calbindin 1, 28kDa 1.31559
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.31244
MAPK14 mitogen-activated protein kinase 14 1.29939
EDA ectodysplasin A 1.29534
FAM126A family with sequence similarity 126, member A 1.28771
FTL ferritin, light polypeptide 1.27247
FTH1 ferritin, heavy polypeptide 1 1.27113
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.26173
NF1 neurofibromin 1 1.25637
ACHE acetylcholinesterase (Yt blood group) 1.24878
FMR1 fragile X mental retardation 1 1.24833
PRNP prion protein 1.23584
MOBP myelin-associated oligodendrocyte basic protein 1.21757
NRG1 neuregulin 1 1.21713
VCAN versican 1.21312
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.19889
RTN4 reticulon 4 1.18867
DCX doublecortin 1.18645
ALB albumin 1.18157
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.17669
TREX1 three prime repair exonuclease 1 1.1758
CRYAB crystallin, alpha B 1.17491
GJC2 gap junction protein, gamma 2, 47kDa 1.17269
TGM5 transglutaminase 5 1.1616
PSEN1 presenilin 1 1.15628
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.15362
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.15229
PVALB parvalbumin 1.14919
CD4 CD4 molecule 1.12925
ZNF804A zinc finger protein 804A 1.12837
IFNB1 interferon, beta 1, fibroblast 1.12128
CPVL carboxypeptidase, vitellogenic-like 1.11686
DNTT DNA nucleotidylexotransferase 1.11243
ENO2 enolase 2 (gamma, neuronal) 1.10933
MAP1B microtubule-associated protein 1B 1.10712
ZFYVE26 zinc finger, FYVE domain containing 26 1.10491
NCAN neurocan 1.08501
GCDH glutaryl-CoA dehydrogenase 1.08015
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 1.07485
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.05369
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 1.03873
NEFH neurofilament, heavy polypeptide 1.03478
COL4A1 collagen, type IV, alpha 1 1.03302
NFASC neurofascin 1.03258
NPY neuropeptide Y 1.03039
LMNB1 lamin B1 1.03039
MAP4 microtubule-associated protein 4 1.02995
IL1B interleukin 1, beta 1.01943
TNF tumor necrosis factor 1.019
NGF nerve growth factor (beta polypeptide) 1.01418
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.00109
CALB2 calbindin 2 0.998908
L2HGDH L-2-hydroxyglutarate dehydrogenase 0.987597
DYX1C1 dyslexia susceptibility 1 candidate 1 0.984122
S100B S100 calcium binding protein B 0.977182
CNTNAP1 contactin associated protein 1 0.977182
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.975882
DARS aspartyl-tRNA synthetase 0.971552
DCDC2 doublecortin domain containing 2 0.965496
KIAA0319 KIAA0319 0.963767
FA2H fatty acid 2-hydroxylase 0.963335
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 0.962039
CHAT choline O-acetyltransferase 0.961607
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.957722
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.940925
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.938777
GJB1 gap junction protein, beta 1, 32kDa 0.93577
GLUL glutamate-ammonia ligase 0.93577
CA4 carbonic anhydrase IV 0.924623
CSF1R colony stimulating factor 1 receptor 0.918633
HEXA hexosaminidase A (alpha polypeptide) 0.910946
BCAN brevican 0.899445
TF transferrin 0.89817
BCHE butyrylcholinesterase 0.890101
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.887133
GAN gigaxonin 0.885862
GLB1 galactosidase, beta 1 0.885015
IL6 interleukin 6 0.884591
IDS iduronate 2-sulfatase 0.883321
FGF2 fibroblast growth factor 2 (basic) 0.879089
OPALIN oligodendrocytic myelin paranodal and inner loop protein 0.876129
SCN1A sodium channel, voltage gated, type I alpha subunit 0.874439
CRP C-reactive protein, pentraxin-related 0.871905
IGF1 insulin-like growth factor 1 (somatomedin C) 0.865999
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.865999
TSC2 tuberous sclerosis 2 0.865155
POMT1 protein-O-mannosyltransferase 1 0.864734
MRI1 methylthioribose-1-phosphate isomerase 1 0.861363
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.859679
SST somatostatin 0.858837
TAC1 tachykinin, precursor 1 0.851686
FKRP fukutin related protein 0.847904
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.841608
IREB2 iron-responsive element binding protein 2 0.83993
GJA1 gap junction protein, alpha 1, 43kDa 0.83448
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.834061
UGT8 UDP glycosyltransferase 8 0.828197
MEMO1 mediator of cell motility 1 0.827778
TARDBP TAR DNA binding protein 0.82736
CST3 cystatin C 0.814397
DES desmin 0.812726
RTN4R reticulon 4 receptor 0.812309
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.812309
ATXN3 ataxin 3 0.809386
PLXNB3 plexin B3 0.803544
GRN granulin 0.800208
ERBB4 erb-b2 receptor tyrosine kinase 4 0.799375
PLD4 phospholipase D family, member 4 0.798958
POLG polymerase (DNA directed), gamma 0.791044
MMP12 matrix metallopeptidase 12 0.789796
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.785635
OMG oligodendrocyte myelin glycoprotein 0.784388
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.780648
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.780232
ADGRG1 adhesion G protein-coupled receptor G1 0.77774
NTF3 neurotrophin 3 0.774004
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.772759
GRM5 glutamate receptor, metabotropic 5 0.772759
CNR1 cannabinoid receptor 1 (brain) 0.771514
DMD dystrophin 0.770685
MMD monocyte to macrophage differentiation-associated 0.768197
CA2 carbonic anhydrase II 0.767368
C10ORF2 chromosome 10 open reading frame 2 0.766539
NTN1 netrin 1 0.760328
PAH phenylalanine hydroxylase 0.759086
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.757845
NKX2-2 NK2 homeobox 2 0.754537
RGMB repulsive guidance molecule family member b 0.751231
CSTB cystatin B (stefin B) 0.749166
MMP9 matrix metallopeptidase 9 0.74834
AP4M1 adaptor-related protein complex 4, mu 1 subunit 0.744627
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.744214
SOD2 superoxide dismutase 2, mitochondrial 0.742976
TNC tenascin C 0.742976
CLDN11 claudin 11 0.741327
BEAN1 brain expressed, associated with NEDD4, 1 0.736794
CARTPT CART prepropeptide 0.735147
GRM3 glutamate receptor, metabotropic 3 0.733912
AP4B1 adaptor-related protein complex 4, beta 1 subunit 0.731031
CFAP47 cilia and flagella associated protein 47 0.729797
APOD apolipoprotein D 0.726507
TUBG1 tubulin, gamma 1 0.724863
SOX10 SRY (sex determining region Y)-box 10 0.724453
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.722398
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.721577
MMP2 matrix metallopeptidase 2 0.721166
CP ceruloplasmin (ferroxidase) 0.717472
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.716651
GRIK1 glutamate receptor, ionotropic, kainate 1 0.714189
TMEM161B transmembrane protein 161B 0.714189
TSC1 tuberous sclerosis 1 0.711319
CSPG4 chondroitin sulfate proteoglycan 4 0.71009
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 0.708041
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.707221
RNASE13 ribonuclease, RNase A family, 13 (non-active) 0.707221
OLIG1 oligodendrocyte transcription factor 1 0.707221
TSPO translocator protein (18kDa) 0.706402
POMT2 protein-O-mannosyltransferase 2 0.705993
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.705583
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.698625
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.695763
TH tyrosine hydroxylase 0.691268
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.690451
TUBB2B tubulin, beta 2B class IIb 0.676987
PLAT plasminogen activator, tissue 0.675765
COMT catechol-O-methyltransferase 0.675765
MAOB monoamine oxidase B 0.666809
TM4SF20 transmembrane 4 L six family member 20 0.665995
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.662336
TYROBP TYRO protein tyrosine kinase binding protein 0.661116
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.650966
INA internexin neuronal intermediate filament protein, alpha 0.650154
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.647721
NEFL neurofilament, light polypeptide 0.647316
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 0.642858
MYT1 myelin transcription factor 1 0.641238
PLLP plasmolipin 0.640428
QDPR quinoid dihydropteridine reductase 0.633144
INS insulin 0.631527
MECP2 methyl CpG binding protein 2 0.630314
GRM2 glutamate receptor, metabotropic 2 0.628697
TPPP tubulin polymerization promoting protein 0.625061
TRIM47 tripartite motif containing 47 0.623043
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.620217
SETD1A SET domain containing 1A 0.614167
CBS cystathionine-beta-synthase 0.610943
SHH sonic hedgehog 0.60893
ABHD11 abhydrolase domain containing 11 0.606112
TNR tenascin R 0.606112
C3ORF58 chromosome 3 open reading frame 58 0.604904
PTPRC protein tyrosine phosphatase, receptor type, C 0.602892
B3GAT1 beta-1,3-glucuronyltransferase 1 0.600881
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.600479
ATF4 activating transcription factor 4 0.599675
PADI2 peptidyl arginine deiminase, type II 0.599675
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.598469
DMPK dystrophia myotonica-protein kinase 0.596862
ACAD11 acyl-CoA dehydrogenase family, member 11 0.596058
GDNF glial cell derived neurotrophic factor 0.592444
RTN4RL1 reticulon 4 receptor-like 1 0.590437
ICAM1 intercellular adhesion molecule 1 0.588832
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.588431
VRK2 vaccinia related kinase 2 0.587629
PMP22 peripheral myelin protein 22 0.587228
S100A4 S100 calcium binding protein A4 0.586828
NAGLU N-acetylglucosaminidase, alpha 0.586828
TSHZ1 teashirt zinc finger homeobox 1 0.584823
FBXL4 F-box and leucine-rich repeat protein 4 0.583621
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.58282
HEPACAM hepatic and glial cell adhesion molecule 0.58282
NRCAM neuronal cell adhesion molecule 0.58282
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.582019
ITGAD integrin, alpha D 0.582019
CNTF ciliary neurotrophic factor 0.580818
ATRN attractin 0.579216
GJB6 gap junction protein, beta 6, 30kDa 0.572418
HLA-C major histocompatibility complex, class I, C 0.571219
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 0.57082
EPT1 ethanolaminephosphotransferase 1 0.568823
ACAD10 acyl-CoA dehydrogenase family, member 10 0.564035
CPLX3 complexin 3 0.562042
ALPL alkaline phosphatase, liver/bone/kidney 0.561245
C7ORF49 chromosome 7 open reading frame 49 0.561245
ALPP alkaline phosphatase, placental 0.560449
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.558856
HTT huntingtin 0.558457
TASP1 taspase, threonine aspartase, 1 0.558059
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 0.557263
MYOM3 myomesin 3 0.556865
TSPAN2 tetraspanin 2 0.556467
QKI QKI, KH domain containing, RNA binding 0.553286
FN1 fibronectin 1 0.552888
SUSD4 sushi domain containing 4 0.549709
ALPPL2 alkaline phosphatase, placental-like 2 0.549312
HTRA1 HtrA serine peptidase 1 0.547724
GAP43 growth associated protein 43 0.547326
PHF1 PHD finger protein 1 0.545739
NCAM1 neural cell adhesion molecule 1 0.545342
ICE2 interactor of little elongation complex ELL subunit 2 0.545342
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 0.544946
CEPT1 choline/ethanolamine phosphotransferase 1 0.540188
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.528323
IVL involucrin 0.527928
BAX BCL2-associated X protein 0.527534
RELN reelin 0.527534
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.526744
ERBB3 erb-b2 receptor tyrosine kinase 3 0.526744
ELOVL1 ELOVL fatty acid elongase 1 0.52635
ACE angiotensin I converting enzyme 0.52556
GAL3ST1 galactose-3-O-sulfotransferase 1 0.525166
PANK2 pantothenate kinase 2 0.525166
TRAPPC9 trafficking protein particle complex 9 0.524771
TPPP2 tubulin polymerization-promoting protein family member 2 0.523588
CD44 CD44 molecule (Indian blood group) 0.521617
FXN frataxin 0.521617
GLS2 glutaminase 2 (liver, mitochondrial) 0.520829
TMEM163 transmembrane protein 163 0.520041
RAB9B RAB9B, member RAS oncogene family 0.518859
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.515317
TTC27 tetratricopeptide repeat domain 27 0.514136
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.514136
MRPL38 mitochondrial ribosomal protein L38 0.514136
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.512564
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.512171
PPP1R32 protein phosphatase 1, regulatory subunit 32 0.511778
TP53 tumor protein p53 0.510206
APOPT1 apoptogenic 1, mitochondrial 0.50942
DPYSL2 dihydropyrimidinase-like 2 0.508242
FGFR2 fibroblast growth factor receptor 2 0.507849
CNTN2 contactin 2 (axonal) 0.507064
SPAG1 sperm associated antigen 1 0.505887
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.505102
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.505102
POMC proopiomelanocortin 0.50471
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.503926
CCL2 chemokine (C-C motif) ligand 2 0.503141
GNPAT glyceronephosphate O-acyltransferase 0.501965
ADSL adenylosuccinate lyase 0.501965
SURF1 surfeit 1 0.499223
MTFMT mitochondrial methionyl-tRNA formyltransferase 0.497657
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.497657
GRM4 glutamate receptor, metabotropic 4 0.495309
FOCAD focadhesin 0.493354
HSPB11 heat shock protein family B (small), member 11 0.492572
FABP7 fatty acid binding protein 7, brain 0.492182
MGAM maltase-glucoamylase 0.491791
CAPS calcyphosine 0.491791
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.490619
NPS neuropeptide S 0.489838
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.485545
CLN3 ceroid-lipofuscinosis, neuronal 3 0.482817
GYPE glycophorin E (MNS blood group) 0.482428
L1CAM L1 cell adhesion molecule 0.479312
KLK6 kallikrein-related peptidase 6 0.478923
RD3 retinal degeneration 3 0.478534
GLS glutaminase 0.478534
NT5E 5'-nucleotidase, ecto (CD73) 0.478145
TTK TTK protein kinase 0.476589
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.476201
NGFR nerve growth factor receptor 0.474258
CALCA calcitonin-related polypeptide alpha 0.473869
CAST calpastatin 0.47348
CCL3 chemokine (C-C motif) ligand 3 0.472704
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.471539
FGFR3 fibroblast growth factor receptor 3 0.470375
GLA galactosidase, alpha 0.468436
DMRTA1 DMRT-like family A1 0.468436
GML glycosylphosphatidylinositol anchored molecule like 0.465723
SETD2 SET domain containing 2 0.465335
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.461852
VWF von Willebrand factor 0.459918
HSPG2 heparan sulfate proteoglycan 2 0.459532
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.459145
GALNS galactosamine (N-acetyl)-6-sulfatase 0.458759
CLCN2 chloride channel, voltage-sensitive 2 0.4576
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.457214
VIM vimentin 0.457214
FGFR1 fibroblast growth factor receptor 1 0.457214
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.456828
ASCL1 achaete-scute family bHLH transcription factor 1 0.454126
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.451428
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.451042
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.449501
ARSH arylsulfatase family, member H 0.447961
NPC1 Niemann-Pick disease, type C1 0.447576
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) 0.444884
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.444884
HSPB6 heat shock protein, alpha-crystallin-related, B6 0.444115
AFG3L2 AFG3-like AAA ATPase 2 0.443347
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.442962
ADGRA1 adhesion G protein-coupled receptor A1 0.442578
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 0.442194
IMPACT impact RWD domain protein 0.441042
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.43989
AGTR1 angiotensin II receptor, type 1 0.43989
VIP vasoactive intestinal peptide 0.439123
GRM1 glutamate receptor, metabotropic 1 0.438739
HMOX1 heme oxygenase 1 0.435672
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.435672
SATB2 SATB homeobox 2 0.434523
SPIN3 spindlin family, member 3 0.434523
C9ORF72 chromosome 9 open reading frame 72 0.433757
PCNA proliferating cell nuclear antigen 0.431077
MLX MLX, MAX dimerization protein 0.431077
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.431077
TSEN34 TSEN34 tRNA splicing endonuclease subunit 0.430312
GMDS GDP-mannose 4,6-dehydratase 0.42993
TGFB1 transforming growth factor, beta 1 0.429547
ERCC6L excision repair cross-complementation group 6-like 0.428401
DNM2 dynamin 2 0.428018
MFN2 mitofusin 2 0.427254
JUN jun proto-oncogene 0.425726
SRPK3 SRSF protein kinase 3 0.421529
SEPT1 septin 1 0.419242
SSR4 signal sequence receptor, delta 0.416576
HDGFRP2 hepatoma-derived growth factor-related protein 2 0.416576
CD163 CD163 molecule 0.415053
LXN latexin 0.414673
TJP1 tight junction protein 1 0.413912
HSPA4 heat shock 70kDa protein 4 0.412391
BCL2L1 BCL2-like 1 0.412011
FOS FBJ murine osteosarcoma viral oncogene homolog 0.41087
PHYH phytanoyl-CoA 2-hydroxylase 0.410111
GPR182 G protein-coupled receptor 182 0.409731
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 0.409351
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.407832
TMPRSS5 transmembrane protease, serine 5 0.407073
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.407073
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.405555
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.404039
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.40328
IL10 interleukin 10 0.402523
HFE hemochromatosis 0.401765
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.398735
ABAT 4-aminobutyrate aminotransferase 0.396087
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.396087
F8 coagulation factor VIII, procoagulant component 0.395331
TYMP thymidine phosphorylase 0.394576
SYN1 synapsin I 0.394197
STMN2 stathmin 2 0.391553
PRDX4 peroxiredoxin 4 0.390044
ETHE1 ethylmalonic encephalopathy 1 0.389666
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.389289
TRH thyrotropin-releasing hormone 0.389289
SGSH N-sulfoglucosamine sulfohydrolase 0.388912
APLP1 amyloid beta (A4) precursor-like protein 1 0.387027
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.38665
PPIE peptidylprolyl isomerase E (cyclophilin E) 0.385896
CTSB cathepsin B 0.385143
TPP1 tripeptidyl peptidase I 0.384766
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.383637
WBP2 WW domain binding protein 2 0.38326
LINGO2 leucine rich repeat and Ig domain containing 2 0.381379
NINJ2 ninjurin 2 0.380251
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.379875
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.379123
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.379123
CXCL10 chemokine (C-X-C motif) ligand 10 0.378372
PSPN persephin 0.375743
EXO1 exonuclease 1 0.375743
PNMA1 paraneoplastic Ma antigen 1 0.375743
UHMK1 U2AF homology motif (UHM) kinase 1 0.371994
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.371994
ECI1 enoyl-CoA delta isomerase 1 0.371245
SOX17 SRY (sex determining region Y)-box 17 0.371245
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.370496
DNAH8 dynein, axonemal, heavy chain 8 0.368624
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 0.366381
CREB1 cAMP responsive element binding protein 1 0.365633
IL1RN interleukin 1 receptor antagonist 0.364139
MANBA mannosidase, beta A, lysosomal 0.362646
MRGPRE MAS-related GPR, member E 0.362273
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.360409
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.359292
CHMP2B charged multivesicular body protein 2B 0.359292
CT45A1 cancer/testis antigen family 45, member A1 0.358919
SPP1 secreted phosphoprotein 1 0.358919
LAMA1 laminin, alpha 1 0.358546
CTXN2 cortexin 2 0.358174
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.357802
LHFP lipoma HMGIC fusion partner 0.357058
PARP1 poly (ADP-ribose) polymerase 1 0.356686
XPA xeroderma pigmentosum, complementation group A 0.356314
STRADA STE20-related kinase adaptor alpha 0.35557
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.35557
CTSD cathepsin D 0.354084
AGER advanced glycosylation end product-specific receptor 0.352227
ERCC8 excision repair cross-complementation group 8 0.351485
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.350372
TRIM37 tripartite motif containing 37 0.34926
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.34926
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.348148
BOD1 biorientation of chromosomes in cell division 1 0.347778
PEX1 peroxisomal biogenesis factor 1 0.347408
CLEC3B C-type lectin domain family 3, member B 0.347038
PSEN2 presenilin 2 0.345558
NTF4 neurotrophin 4 0.345188
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.344818
MAST3 microtubule associated serine/threonine kinase 3 0.344818
PNISR PNN-interacting serine/arginine-rich protein 0.344818
THBD thrombomodulin 0.342233
PEX26 peroxisomal biogenesis factor 26 0.341495
FYN FYN proto-oncogene, Src family tyrosine kinase 0.338914
NOS3 nitric oxide synthase 3 (endothelial cell) 0.338545
MFGE8 milk fat globule-EGF factor 8 protein 0.33744
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.337072
KCTD11 potassium channel tetramerization domain containing 11 0.3356
SPAST spastin 0.333763
PHF6 PHD finger protein 6 0.333763
STMN4 stathmin-like 4 0.333028
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.33046
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.329361
LAMB1 laminin, beta 1 0.328262
ETFDH electron-transferring-flavoprotein dehydrogenase 0.328262
MMP3 matrix metallopeptidase 3 0.327896
HEXB hexosaminidase B (beta polypeptide) 0.327164
CTXN1 cortexin 1 0.326798
CCDC91 coiled-coil domain containing 91 0.326432
CD34 CD34 molecule 0.326432
IFNA1 interferon, alpha 1 0.325701
TBX1 T-box 1 0.325335
GPX1 glutathione peroxidase 1 0.32497
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.32497
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.324605
GJC3 gap junction protein, gamma 3, 30.2kDa 0.324239
NRP1 neuropilin 1 0.321685
TFRC transferrin receptor 0.319134
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.318407
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.318042
CA12 carbonic anhydrase XII 0.317315
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.315861
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 0.315498
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.31332
OCLN occludin 0.311507
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.311507
BMP4 bone morphogenetic protein 4 0.309697
PADI4 peptidyl arginine deiminase, type IV 0.307528
ACRBP acrosin binding protein 0.307528
NDRG2 NDRG family member 2 0.306444
PTH parathyroid hormone 0.306083
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.305722
UBE3A ubiquitin protein ligase E3A 0.304279
CAT catalase 0.303919
PHGDH phosphoglycerate dehydrogenase 0.303919
PEX2 peroxisomal biogenesis factor 2 0.303559
PBX4 pre-B-cell leukemia homeobox 4 0.303198
ACAD9 acyl-CoA dehydrogenase family, member 9 0.302838
MAGEA8 melanoma antigen family A8 0.301758
ERVW-1 endogenous retrovirus group W, member 1 0.299242
SLC25A27 solute carrier family 25, member 27 0.299242
FAF2 Fas associated factor family member 2 0.298883
NLGN3 neuroligin 3 0.298524
SUMF1 sulfatase modifying factor 1 0.29673
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.294939
MME membrane metallo-endopeptidase 0.294581
EPHA3 EPH receptor A3 0.293508
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.292793
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.292436
MRPL19 mitochondrial ribosomal protein L19 0.291008
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.290652
FGF1 fibroblast growth factor 1 (acidic) 0.287803
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.286381
PANK1 pantothenate kinase 1 0.286381
NBN nibrin 0.285316
THY1 Thy-1 cell surface antigen 0.283899
PSD3 pleckstrin and Sec7 domain containing 3 0.283545
CTC1 CTS telomere maintenance complex component 1 0.28213
MIR137 microRNA 137 0.28213
MGAT4C MGAT4 family, member C 0.280364
LARGE like-glycosyltransferase 0.277549
GSTA3 glutathione S-transferase alpha 3 0.276846
GORAB golgin, RAB6-interacting 0.276495
TMC6 transmembrane channel-like 6 0.275794
GSTA4 glutathione S-transferase alpha 4 0.275094
GSTA2 glutathione S-transferase alpha 2 0.275094
MPRIP myosin phosphatase Rho interacting protein 0.274394
GUSB glucuronidase, beta 0.274045
HK1 hexokinase 1 0.274045
GRID1 glutamate receptor, ionotropic, delta 1 0.273696
COX5A cytochrome c oxidase subunit Va 0.273346
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.273346
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.271952
BCAP31 B-cell receptor-associated protein 31 0.271952
VCAM1 vascular cell adhesion molecule 1 0.271604
CST7 cystatin F (leukocystatin) 0.271256
GSTA1 glutathione S-transferase alpha 1 0.271256
PROS1 protein S (alpha) 0.270909
HLA-E major histocompatibility complex, class I, E 0.270561
ARHGAP26 Rho GTPase activating protein 26 0.269521
NTN3 netrin 3 0.269174
STAC SH3 and cysteine rich domain 0.268828
KDM5C lysine (K)-specific demethylase 5C 0.268137
S1PR5 sphingosine-1-phosphate receptor 5 0.267791
CLIP1 CAP-GLY domain containing linker protein 1 0.267446
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.266757
F3 coagulation factor III (thromboplastin, tissue factor) 0.265725
RNASET2 ribonuclease T2 0.265725
PROM1 prominin 1 0.265038
SLITRK5 SLIT and NTRK-like family, member 5 0.264696
SAMHD1 SAM domain and HD domain 1 0.264011
TLR2 toll-like receptor 2 0.263327
GBA glucosidase, beta, acid 0.262645
LIMK1 LIM domain kinase 1 0.261624
FUS FUS RNA binding protein 0.261284
PAX6 paired box 6 0.260267
MPO myeloperoxidase 0.259929
S100A6 S100 calcium binding protein A6 0.259929
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.25858
SOX2 SRY (sex determining region Y)-box 2 0.257237
CA13 carbonic anhydrase XIII 0.256568
MARCKSL1 MARCKS-like 1 0.2559
GPX5 glutathione peroxidase 5 0.2559
FGD1 FYVE, RhoGEF and PH domain containing 1 0.255234
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.254902
IL9 interleukin 9 0.25457
GPX4 glutathione peroxidase 4 0.25457
MIR15B microRNA 15b 0.253908
F2 coagulation factor II (thrombin) 0.25259
COL6A1 collagen, type VI, alpha 1 0.252261
TLR4 toll-like receptor 4 0.251606
TBR1 T-box, brain, 1 0.250953
NOG noggin 0.249977
LINGO1 leucine rich repeat and Ig domain containing 1 0.249006
THAP1 THAP domain containing, apoptosis associated protein 1 0.248361
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.248361
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.247399
TREM2 triggering receptor expressed on myeloid cells 2 0.24676
IVD isovaleryl-CoA dehydrogenase 0.24676
EIF6 eukaryotic translation initiation factor 6 0.245807
PIPOX pipecolic acid oxidase 0.245491
RPS4X ribosomal protein S4, X-linked 0.245491
DISC1 disrupted in schizophrenia 1 0.245175
AUH AU RNA binding protein/enoyl-CoA hydratase 0.245175
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.24486
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.243294
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.242983
PFAS phosphoribosylformylglycinamidine synthase 0.242672
DCC DCC netrin 1 receptor 0.241132
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.240826
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.240216
KIAA0226 KIAA0226 0.239913
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.238706
CNTNAP2 contactin associated protein-like 2 0.238406
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.238108
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.237513
RANGRF RAN guanine nucleotide release factor 0.237513
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.236627
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.236627
PLG plasminogen 0.234016
MYO1D myosin ID 0.233731
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.233162
GABARAP GABA(A) receptor-associated protein 0.232599
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.232599
PTF1A pancreas specific transcription factor, 1a 0.23176
SDF4 stromal cell derived factor 4 0.231206
NTSR1 neurotensin receptor 1 (high affinity) 0.229299
LCK LCK proto-oncogene, Src family tyrosine kinase 0.228497
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.22797
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.22797
GSK3B glycogen synthase kinase 3 beta 0.227707
NOTCH1 notch 1 0.227707
ZFP64 ZFP64 zinc finger protein 0.227445
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.226926
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.225144
HSPB1 heat shock 27kDa protein 1 0.225144
PLA2G1B phospholipase A2, group IB (pancreas) 0.225144
DDHD2 DDHD domain containing 2 0.224645
RBPMS RNA binding protein with multiple splicing 0.224645
NRXN1 neurexin 1 0.223419
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.223177
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.223177
MAOA monoamine oxidase A 0.222938
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.222224
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.221989
C1QB complement component 1, q subcomponent, B chain 0.220152
NPC2 Niemann-Pick disease, type C2 0.219928
DDHD1 DDHD domain containing 1 0.219928
GRIK3 glutamate receptor, ionotropic, kainate 3 0.219485
CLDN5 claudin 5 0.219047
HBA2 hemoglobin, alpha 2 0.218613
NHEJ1 nonhomologous end-joining factor 1 0.218398
PICALM phosphatidylinositol binding clathrin assembly protein 0.218186
TKT transketolase 0.217346
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.217346
CRLF1 cytokine receptor-like factor 1 0.217346
TECR trans-2,3-enoyl-CoA reductase 0.217139
RIN2 Ras and Rab interactor 2 0.216528
NOSIP nitric oxide synthase interacting protein 0.216126
IARS isoleucyl-tRNA synthetase 0.21573
CDC123 cell division cycle 123 0.214765
HSPB3 heat shock 27kDa protein 3 0.214576
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.214202
PYGB phosphorylase, glycogen; brain 0.21365
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.213291
NTS neurotensin 0.213291
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.213291
PYGL phosphorylase, glycogen, liver 0.213112
HGFAC HGF activator 0.212586
RIC3 RIC3 acetylcholine receptor chaperone 0.212586
USP8 ubiquitin specific peptidase 8 0.212586
IFT122 intraflagellar transport 122 0.198278
PDIA4 protein disulfide isomerase family A, member 4 0.196826
ETNK1 ethanolamine kinase 1 0.195237
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.195022
ARHGAP4 Rho GTPase activating protein 4 0.194969
CFH complement factor H 0.193991
PDIA6 protein disulfide isomerase family A, member 6 0.193951
STAU1 staufen double-stranded RNA binding protein 1 0.193635
KIF1A kinesin family member 1A 0.193315
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.193205
ACSL1 acyl-CoA synthetase long-chain family member 1 0.192646
HAGH hydroxyacylglutathione hydrolase 0.192264
PRMT5 protein arginine methyltransferase 5 0.191901
TST thiosulfate sulfurtransferase (rhodanese) 0.190466
SNHG12 small nucleolar RNA host gene 12 0.189829
IDUA iduronidase, alpha-L- 0.189767
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.189357
PRPF4B pre-mRNA processing factor 4B 0.189282
TLK1 tousled-like kinase 1 0.189108
MUSK muscle, skeletal, receptor tyrosine kinase 0.189064
STK4 serine/threonine kinase 4 0.188441
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.18799
PRKD3 protein kinase D3 0.187868
EPGN epithelial mitogen 0.187856
PLK4 polo-like kinase 4 0.18777
PDIA3 protein disulfide isomerase family A, member 3 0.18752
FLOT1 flotillin 1 0.187056
HIST1H2AJ histone cluster 1, H2aj 0.185704
HIST1H2AD histone cluster 1, H2ad 0.185704
HIST1H2AH histone cluster 1, H2ah 0.185689
H2AFJ H2A histone family, member J 0.185659
H2AFY2 H2A histone family, member Y2 0.18557
HIST1H2AM histone cluster 1, H2am 0.185495
H2AFB1 H2A histone family, member B1 0.18548
H2AFV H2A histone family, member V 0.185465
H2AFB2 H2A histone family, member B2 0.185465
HIST1H2AG histone cluster 1, H2ag 0.185419
PARK7 parkinson protein 7 0.185419
HIST1H2AB histone cluster 1, H2ab 0.18519
HIST1H2AE histone cluster 1, H2ae 0.18519
DAND5 DAN domain family member 5, BMP antagonist 0.184893
H2AFY H2A histone family, member Y 0.184375
MARK2 MAP/microtubule affinity-regulating kinase 2 0.18373
UGCG UDP-glucose ceramide glucosyltransferase 0.183104
CSNK2B casein kinase 2, beta polypeptide 0.182751
IL2RG interleukin 2 receptor, gamma 0.182504
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.182349
VLDLR very low density lipoprotein receptor 0.182054
ANXA7 annexin A7 0.181974
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.180931
CHKA choline kinase alpha 0.180779
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.180535
PON1 paraoxonase 1 0.180468
ASRGL1 asparaginase like 1 0.179417
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.179022
CYCS cytochrome c, somatic 0.178251
PYGM phosphorylase, glycogen, muscle 0.177296
CTSC cathepsin C 0.176953
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.175339
GSN gelsolin 0.175243
KL klotho 0.174515
MAPK1 mitogen-activated protein kinase 1 0.173396
DLL1 delta-like 1 (Drosophila) 0.17258
LATS1 large tumor suppressor kinase 1 0.17258
SDPR serum deprivation response 0.170362