cerebral cortical neuron Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description One of the nerve cells that make up the cortex of the brain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004102)
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Genes

752 proteins co-occuring with the tissue cerebral cortical neuron in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
BDNF brain-derived neurotrophic factor 2.34298
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.05942
CDK5 cyclin-dependent kinase 5 1.9662
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.95408
NGF nerve growth factor (beta polypeptide) 1.77731
RELN reelin 1.75874
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.69848
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.69599
MAPT microtubule-associated protein tau 1.64356
PVALB parvalbumin 1.63456
CREB1 cAMP responsive element binding protein 1 1.63306
MAP2 microtubule-associated protein 2 1.63206
BAX BCL2-associated X protein 1.61758
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.60216
NT5C1A 5'-nucleotidase, cytosolic IA 1.49067
HTT huntingtin 1.45797
JUN jun proto-oncogene 1.39376
PSEN1 presenilin 1 1.38002
GSK3B glycogen synthase kinase 3 beta 1.37453
FOS FBJ murine osteosarcoma viral oncogene homolog 1.36541
NTF3 neurotrophin 3 1.36177
SYP synaptophysin 1.33727
APP amyloid beta (A4) precursor protein 1.33681
SYN1 synapsin I 1.33319
CALB2 calbindin 2 1.2913
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.28009
CALB1 calbindin 1, 28kDa 1.2774
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.24878
BACE1 beta-site APP-cleaving enzyme 1 1.24744
NTF4 neurotrophin 4 1.2461
NTN1 netrin 1 1.23494
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 1.21713
MAP1B microtubule-associated protein 1B 1.20156
SOD2 superoxide dismutase 2, mitochondrial 1.19934
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.198
MAPK8 mitogen-activated protein kinase 8 1.18379
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.16693
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.16515
GRM5 glutamate receptor, metabotropic 5 1.1616
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.15451
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.14786
VLDLR very low density lipoprotein receptor 1.1452
RTN4R reticulon 4 receptor 1.13944
SST somatostatin 1.1359
DCX doublecortin 1.12881
MAP4 microtubule-associated protein 4 1.12527
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 1.11951
PARP1 poly (ADP-ribose) polymerase 1 1.11907
GRM1 glutamate receptor, metabotropic 1 1.1027
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.09872
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.09562
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.08811
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.08722
PRNP prion protein 1.08722
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.08678
ACHE acetylcholinesterase (Yt blood group) 1.08545
TP53 tumor protein p53 1.0775
NEFH neurofilament, heavy polypeptide 1.0775
NGB neuroglobin 1.07176
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.0625
ASIC1 acid sensing (proton gated) ion channel 1 1.06074
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.05369
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.04401
FYN FYN proto-oncogene, Src family tyrosine kinase 1.03697
LRRK2 leucine-rich repeat kinase 2 1.03083
NPY neuropeptide Y 1.02776
MAPK3 mitogen-activated protein kinase 3 1.02557
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.00981
NEUROG2 neurogenin 2 0.998908
SEZ6 seizure related 6 homolog (mouse) 0.998037
TBR1 T-box, brain, 1 0.980651
DNM1L dynamin 1-like 0.977182
DLG4 discs, large homolog 4 (Drosophila) 0.967225
HSPA4 heat shock 70kDa protein 4 0.962039
HDAC9 histone deacetylase 9 0.956859
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.951685
FGF2 fibroblast growth factor 2 (basic) 0.943075
GDNF glial cell derived neurotrophic factor 0.939636
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.939206
ATL1 atlastin GTPase 1 0.934482
DPYSL3 dihydropyrimidinase-like 3 0.934482
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.928906
MGAM maltase-glucoamylase 0.926336
PLXNA4 plexin A4 0.925907
BCL2L1 BCL2-like 1 0.925907
NDFIP1 Nedd4 family interacting protein 1 0.920344
CHAT choline O-acetyltransferase 0.920344
NPS neuropeptide S 0.917351
APOE apolipoprotein E 0.914361
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.901998
CNR1 cannabinoid receptor 1 (brain) 0.901147
CRMP1 collapsin response mediator protein 1 0.900721
RND2 Rho family GTPase 2 0.900296
TRNAU1AP tRNA selenocysteine 1 associated protein 1 0.899871
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.897745
DPYSL2 dihydropyrimidinase-like 2 0.896895
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.892223
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.882051
RTN4 reticulon 4 0.879512
PLXNA3 plexin A3 0.878243
NGFR nerve growth factor receptor 0.876552
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.874439
DNTT DNA nucleotidylexotransferase 0.872327
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.869373
NLGN1 neuroligin 1 0.862206
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.860942
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.857153
SPAST spastin 0.856732
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.856312
IGF1 insulin-like growth factor 1 (somatomedin C) 0.856312
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.852948
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.850005
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.846644
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.841608
SH3RF1 SH3 domain containing ring finger 1 0.83951
ZDHHC13 zinc finger, DHHC-type containing 13 0.837833
ATP13A2 ATPase type 13A2 0.837414
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.83448
GAP43 growth associated protein 43 0.832385
MECP2 methyl CpG binding protein 2 0.829453
CCK cholecystokinin 0.823594
L1CAM L1 cell adhesion molecule 0.823594
MFN1 mitofusin 1 0.821502
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 0.816904
PTEN phosphatase and tensin homolog 0.816486
NDEL1 nudE neurodevelopment protein 1-like 1 0.807299
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.803544
ARC activity-regulated cytoskeleton-associated protein 0.801876
MRAP melanocortin 2 receptor accessory protein 0.799791
GRM2 glutamate receptor, metabotropic 2 0.799791
HMOX1 heme oxygenase 1 0.799375
SATB2 SATB homeobox 2 0.798125
PHF1 PHD finger protein 1 0.797291
MPPED1 metallophosphoesterase domain containing 1 0.796874
KIDINS220 kinase D-interacting substrate, 220kDa 0.796458
CHMP2B charged multivesicular body protein 2B 0.788547
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.788131
CAST calpastatin 0.786052
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.783972
CDC42 cell division cycle 42 0.781478
LMO4 LIM domain only 4 0.779816
MKL1 megakaryoblastic leukemia (translocation) 1 0.77774
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.776909
PPT1 palmitoyl-protein thioesterase 1 0.77027
GFAP glial fibrillary acidic protein 0.769441
GRIK1 glutamate receptor, ionotropic, kainate 1 0.768612
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.767783
SNX14 sorting nexin 14 0.766125
NEO1 neogenin 1 0.763226
RYR1 ryanodine receptor 1 (skeletal) 0.76157
MT3 metallothionein 3 0.759086
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.756604
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.756191
CAT catalase 0.752884
PLAT plasminogen activator, tissue 0.749166
TH tyrosine hydroxylase 0.749166
ELP3 elongator acetyltransferase complex subunit 3 0.747515
DBN1 drebrin 1 0.743801
SYT1 synaptotagmin I 0.739266
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.738854
DNAH8 dynein, axonemal, heavy chain 8 0.732265
ADAM10 ADAM metallopeptidase domain 10 0.731442
NES nestin 0.72733
FOXRED2 FAD-dependent oxidoreductase domain containing 2 0.726918
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.725685
APH1A APH1A gamma secretase subunit 0.725274
PTN pleiotrophin 0.724453
TUBA1A tubulin, alpha 1a 0.722398
APLP1 amyloid beta (A4) precursor-like protein 1 0.720755
CBLN2 cerebellin 2 precursor 0.7146
EEF2K eukaryotic elongation factor 2 kinase 0.711729
PLA2G1B phospholipase A2, group IB (pancreas) 0.71009
REST RE1-silencing transcription factor 0.70927
NPTX1 neuronal pentraxin I 0.70886
BCL2 B-cell CLL/lymphoma 2 0.708041
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.707221
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.706402
TARDBP TAR DNA binding protein 0.705993
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa 0.703127
NRP1 neuropilin 1 0.703127
ESR1 estrogen receptor 1 0.702308
NCAN neurocan 0.699444
LDLR low density lipoprotein receptor 0.698625
GRM4 glutamate receptor, metabotropic 4 0.698216
NCK1 NCK adaptor protein 1 0.697399
FEZF2 FEZ family zinc finger 2 0.696172
RICTOR RPTOR independent companion of MTOR, complex 2 0.693719
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.693311
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.679025
ADNP activity-dependent neuroprotector homeobox 0.677803
EMX1 empty spiracles homeobox 1 0.676172
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.667215
NCK2 NCK adaptor protein 2 0.666809
CDK4 cyclin-dependent kinase 4 0.665588
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 0.663962
EFR3A EFR3 homolog A (S. cerevisiae) 0.661116
IL1B interleukin 1, beta 0.66071
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.657054
DISC1 disrupted in schizophrenia 1 0.656648
ZBTB18 zinc finger and BTB domain containing 18 0.656242
BECN1 beclin 1, autophagy related 0.655024
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.652589
EEF2 eukaryotic translation elongation factor 2 0.650966
GLI4 GLI family zinc finger 4 0.647721
IDI1 isopentenyl-diphosphate delta isomerase 1 0.6461
FAM134C family with sequence similarity 134, member C 0.645695
NRP2 neuropilin 2 0.645695
CRTC1 CREB regulated transcription coactivator 1 0.64529
FRS3 fibroblast growth factor receptor substrate 3 0.644884
CLN5 ceroid-lipofuscinosis, neuronal 5 0.643263
TAOK2 TAO kinase 2 0.642048
TNF tumor necrosis factor 0.641643
CTNND2 catenin (cadherin-associated protein), delta 2 0.639619
PPARG peroxisome proliferator-activated receptor gamma 0.638809
SORT1 sortilin 1 0.638404
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.637999
GPX1 glutathione peroxidase 1 0.636785
INA internexin neuronal intermediate filament protein, alpha 0.635572
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.635167
NRN1 neuritin 1 0.633549
FGF1 fibroblast growth factor 1 (acidic) 0.633549
SUMO3 small ubiquitin-like modifier 3 0.63274
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.632335
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.631931
SIRT1 sirtuin 1 0.629506
GPX4 glutathione peroxidase 4 0.629101
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.624254
TSC2 tuberous sclerosis 2 0.623043
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.621831
ATG7 autophagy related 7 0.621024
DLG1 discs, large homolog 1 (Drosophila) 0.61941
LIN7B lin-7 homolog B (C. elegans) 0.616183
FOXG1 forkhead box G1 0.615377
FIG4 FIG4 phosphoinositide 5-phosphatase 0.614974
EGR1 early growth response 1 0.612958
CABP1 calcium binding protein 1 0.61175
PARK2 parkin RBR E3 ubiquitin protein ligase 0.610541
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.608527
GJD2 gap junction protein, delta 2, 36kDa 0.607319
APLP2 amyloid beta (A4) precursor-like protein 2 0.605709
KIF17 kinesin family member 17 0.604502
SUMO2 small ubiquitin-like modifier 2 0.603295
NCSTN nicastrin 0.603295
OPRM1 opioid receptor, mu 1 0.602088
KIAA0196 KIAA0196 0.601686
FLNA filamin A, alpha 0.601283
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.596862
GPX5 glutathione peroxidase 5 0.594853
CUX2 cut-like homeobox 2 0.59124
GRM7 glutamate receptor, metabotropic 7 0.590437
CNTF ciliary neurotrophic factor 0.589635
AUTS2 autism susceptibility candidate 2 0.586828
H3F3A H3 histone, family 3A 0.585625
H3F3B H3 histone, family 3B (H3.3B) 0.585625
SH3GL3 SH3-domain GRB2-like 3 0.584422
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.584022
CBLN1 cerebellin 1 precursor 0.584022
RGMA repulsive guidance molecule family member a 0.581218
ATF4 activating transcription factor 4 0.581218
SNX12 sorting nexin 12 0.580017
NEUROD6 neuronal differentiation 6 0.578816
UBL3 ubiquitin-like 3 0.578416
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.576816
HMOX2 heme oxygenase 2 0.576415
FGF13 fibroblast growth factor 13 0.574816
ZNF345 zinc finger protein 345 0.574816
OTX1 orthodenticle homeobox 1 0.574017
TIAM2 T-cell lymphoma invasion and metastasis 2 0.573616
GRN granulin 0.571619
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.571219
NRG1 neuregulin 1 0.569222
ZDHHC17 zinc finger, DHHC-type containing 17 0.568424
ENO2 enolase 2 (gamma, neuronal) 0.566828
EFHD2 EF-hand domain family, member D2 0.563637
SNAPIN SNAP-associated protein 0.563238
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.56284
MARCKS myristoylated alanine-rich protein kinase C substrate 0.561245
CBLN4 cerebellin 4 precursor 0.560449
HDAC1 histone deacetylase 1 0.560449
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.558059
DTNBP1 dystrobrevin binding protein 1 0.55607
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.555274
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.555274
SYNJ1 synaptojanin 1 0.55408
CARD17 caspase recruitment domain family, member 17 0.553286
KEAP1 kelch-like ECH-associated protein 1 0.550901
ATG5 autophagy related 5 0.550503
HSF1 heat shock transcription factor 1 0.548517
UNC5A unc-5 homolog A (C. elegans) 0.547326
DSCAM Down syndrome cell adhesion molecule 0.544946
PAX6 paired box 6 0.54217
EPHB3 EPH receptor B3 0.541377
MSN moesin 0.540585
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.538209
EFNA5 ephrin-A5 0.537021
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.535042
PKN1 protein kinase N1 0.534251
AGER advanced glycosylation end product-specific receptor 0.533856
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.531089
RYR3 ryanodine receptor 3 0.531089
EPHA4 EPH receptor A4 0.528323
MAPK9 mitogen-activated protein kinase 9 0.527534
ADCY2 adenylate cyclase 2 (brain) 0.52556
OMG oligodendrocyte myelin glycoprotein 0.524377
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.523588
DDIT3 DNA-damage-inducible transcript 3 0.520435
EMX2 empty spiracles homeobox 2 0.518859
FGF12 fibroblast growth factor 12 0.518072
KAAG1 kidney associated antigen 1 0.516497
GLB1 galactosidase, beta 1 0.516104
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.515317
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.514924
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 0.514136
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.513743
TAC1 tachykinin, precursor 1 0.51335
PDYN prodynorphin 0.512957
TIAM1 T-cell lymphoma invasion and metastasis 1 0.512564
MAPK14 mitogen-activated protein kinase 14 0.512171
SHROOM3 shroom family member 3 0.510599
CTSD cathepsin D 0.509813
HP1BP3 heterochromatin protein 1, binding protein 3 0.509027
HDAC6 histone deacetylase 6 0.509027
HDGFRP3 hepatoma-derived growth factor, related protein 3 0.507457
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.50471
CCND1 cyclin D1 0.504318
BCHE butyrylcholinesterase 0.504318
SH3RF2 SH3 domain containing ring finger 2 0.50275
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.501574
ANXA5 annexin A5 0.50079
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.50079
DNM2 dynamin 2 0.499615
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.498048
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.497657
TSC1 tuberous sclerosis 1 0.496874
LIN7A lin-7 homolog A (C. elegans) 0.496092
LSAMP limbic system-associated membrane protein 0.495701
PSAP prosaposin 0.494528
PPIF peptidylprolyl isomerase F 0.494136
MYEF2 myelin expression factor 2 0.493354
SNCB synuclein, beta 0.493354
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.490619
CEP170 centrosomal protein 170kDa 0.489447
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.489057
MSMO1 methylsterol monooxygenase 1 0.489057
MAP1A microtubule-associated protein 1A 0.488276
VRK3 vaccinia related kinase 3 0.488276
PRDM10 PR domain containing 10 0.487496
EPHB2 EPH receptor B2 0.487496
HEXA hexosaminidase A (alpha polypeptide) 0.486716
LINGO1 leucine rich repeat and Ig domain containing 1 0.485156
DYX1C1 dyslexia susceptibility 1 candidate 1 0.484766
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.483986
KALRN kalirin, RhoGEF kinase 0.483206
PDE4A phosphodiesterase 4A, cAMP-specific 0.482817
CPNE4 copine IV 0.481259
ASCL1 achaete-scute family bHLH transcription factor 1 0.48048
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.478145
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.476979
DCDC2 doublecortin domain containing 2 0.475034
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.47348
AFG3L2 AFG3-like AAA ATPase 2 0.47348
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.472704
NOTCH1 notch 1 0.472704
ENDOG endonuclease G 0.472704
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.469211
STIM2 stromal interaction molecule 2 0.466885
PNOC prepronociceptin 0.466498
NRGN neurogranin (protein kinase C substrate, RC3) 0.463013
KIAA0319 KIAA0319 0.462626
SIRT3 sirtuin 3 0.462626
HIP1 huntingtin interacting protein 1 0.461078
MAOA monoamine oxidase A 0.461078
NDE1 nudE neurodevelopment protein 1 0.459918
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.459532
PTPRD protein tyrosine phosphatase, receptor type, D 0.458759
HIST1H1E histone cluster 1, H1e 0.458373
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.4576
ELANE elastase, neutrophil expressed 0.457214
INS insulin 0.457214
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.456442
GLS2 glutaminase 2 (liver, mitochondrial) 0.45567
RDX radixin 0.454898
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.454126
MBP myelin basic protein 0.454126
CUX1 cut-like homeobox 1 0.45374
KIAA0319L KIAA0319-like 0.453355
C2CD4A C2 calcium-dependent domain containing 4A 0.451813
GLS glutaminase 0.450271
NRD1 nardilysin (N-arginine dibasic convertase) 0.449886
RND3 Rho family GTPase 3 0.449116
MYT1L myelin transcription factor 1-like 0.448346
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 0.448346
IGKV1-17 immunoglobulin kappa variable 1-17 0.447192
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.445653
LXN latexin 0.444884
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.441042
KAT5 K(lysine) acetyltransferase 5 0.439123
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.438739
FKTN fukutin 0.438356
EFNB1 ephrin-B1 0.437589
NTS neurotensin 0.436438
GPRIN1 G protein regulated inducer of neurite outgrowth 1 0.434523
KCNIP1 Kv channel interacting protein 1 0.433757
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.430312
DCC DCC netrin 1 receptor 0.42993
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.429165
CREBBP CREB binding protein 0.42649
FUS FUS RNA binding protein 0.423818
PANX1 pannexin 1 0.423436
SIRT2 sirtuin 2 0.423436
BACE2 beta-site APP-cleaving enzyme 2 0.423054
STMN2 stathmin 2 0.421148
HES6 hes family bHLH transcription factor 6 0.420766
EFNB3 ephrin-B3 0.420766
RBM10 RNA binding motif protein 10 0.41848
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.418099
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.417718
VIP vasoactive intestinal peptide 0.417337
NFE2L2 nuclear factor, erythroid 2-like 2 0.416957
ZDHHC9 zinc finger, DHHC-type containing 9 0.415053
GCLC glutamate-cysteine ligase, catalytic subunit 0.411251
PTRF polymerase I and transcript release factor 0.411251
SEPT14 septin 14 0.410111
FGF17 fibroblast growth factor 17 0.406694
PLXNB2 plexin B2 0.406315
FRS2 fibroblast growth factor receptor substrate 2 0.405935
CDKL3 cyclin-dependent kinase-like 3 0.405555
MAP2K7 mitogen-activated protein kinase kinase 7 0.405555
FDPS farnesyl diphosphate synthase 0.405176
AATF apoptosis antagonizing transcription factor 0.404039
CEP120 centrosomal protein 120kDa 0.404039
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.402901
RAB3A RAB3A, member RAS oncogene family 0.399871
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.398735
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.398357
ERBB4 erb-b2 receptor tyrosine kinase 4 0.397979
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.397979
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.396465
DOK6 docking protein 6 0.396087
ATM ATM serine/threonine kinase 0.394953
CTSB cathepsin B 0.394576
LOX lysyl oxidase 0.393064
NEFM neurofilament, medium polypeptide 0.392309
CDKL5 cyclin-dependent kinase-like 5 0.391931
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.391553
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.389666
CXCL12 chemokine (C-X-C motif) ligand 12 0.388912
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.388535
DAP death-associated protein 0.388535
UNC80 unc-80 homolog (C. elegans) 0.388158
FGFR1 fibroblast growth factor receptor 1 0.388158
JAK2 Janus kinase 2 0.38665
IDE insulin-degrading enzyme 0.385896
LHX6 LIM homeobox 6 0.385896
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.384766
GUK1 guanylate kinase 1 0.384013
PALLD palladin, cytoskeletal associated protein 0.383637
GPHN gephyrin 0.381755
PTPRF protein tyrosine phosphatase, receptor type, F 0.380627
CSDC2 cold shock domain containing C2, RNA binding 0.379499
NEUROG1 neurogenin 1 0.379123
CLSTN3 calsyntenin 3 0.379123
POU3F2 POU class 3 homeobox 2 0.378372
LRRTM3 leucine rich repeat transmembrane neuronal 3 0.377245
SPIRE2 spire-type actin nucleation factor 2 0.376119
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.376119
NSF N-ethylmaleimide-sensitive factor 0.376119
KCNIP3 Kv channel interacting protein 3, calsenilin 0.373868
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.373493
UNC5B unc-5 homolog B (C. elegans) 0.371994
KLK1 kallikrein 1 0.370121
GBP3 guanylate binding protein 3 0.368998
KIF3A kinesin family member 3A 0.36825
LINS lines homolog (Drosophila) 0.366754
PCLO piccolo presynaptic cytomatrix protein 0.365633
SIRT5 sirtuin 5 0.365633
PLA2G3 phospholipase A2, group III 0.36526
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.364886
CEP152 centrosomal protein 152kDa 0.364886
DLG3 discs, large homolog 3 (Drosophila) 0.364513
ATF6 activating transcription factor 6 0.364139
KLHL20 kelch-like family member 20 0.36302
SCN3A sodium channel, voltage gated, type III alpha subunit 0.362646
SIK1 salt-inducible kinase 1 0.361527
PPT2 palmitoyl-protein thioesterase 2 0.361155
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.360409
SNTG2 syntrophin, gamma 2 0.359292
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.358546
CNTN2 contactin 2 (axonal) 0.358174
SIRT7 sirtuin 7 0.358174
ADORA1 adenosine A1 receptor 0.357802
PLXNA1 plexin A1 0.357802
HOMER1 homer scaffolding protein 1 0.35557
PICK1 protein interacting with PRKCA 1 0.355198
SH2B1 SH2B adaptor protein 1 0.352969
PLXNB1 plexin B1 0.351856
MAG myelin associated glycoprotein 0.350372
HIST2H3A histone cluster 2, H3a 0.350001
HIST2H3D histone cluster 2, H3d 0.350001
HIST2H3C histone cluster 2, H3c 0.350001
MAP2K1 mitogen-activated protein kinase kinase 1 0.350001
ATXN1 ataxin 1 0.34926
DIABLO diablo, IAP-binding mitochondrial protein 0.344079
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.344079
KLK9 kallikrein-related peptidase 9 0.34371
SIRT4 sirtuin 4 0.342602
AIF1 allograft inflammatory factor 1 0.341495
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 0.340757
FXR2 fragile X mental retardation, autosomal homolog 2 0.340757
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.337072
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.3356
DCHS1 dachsous cadherin-related 1 0.333763
CORT cortistatin 0.332661
TTBK1 tau tubulin kinase 1 0.332661
GLUL glutamate-ammonia ligase 0.331927
ARHGAP33 Rho GTPase activating protein 33 0.331194
MEF2C myocyte enhancer factor 2C 0.331194
TGFB2 transforming growth factor, beta 2 0.330094
MFN2 mitofusin 2 0.329361
CNTLN centlein, centrosomal protein 0.328628
M6PR mannose-6-phosphate receptor (cation dependent) 0.328262
WNT3A wingless-type MMTV integration site family, member 3A 0.32753
MYO10 myosin X 0.327164
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.327164
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.326432
GRB2 growth factor receptor-bound protein 2 0.326432
FASLG Fas ligand (TNF superfamily, member 6) 0.326067
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.325335
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.323509
SCAMP3 secretory carrier membrane protein 3 0.323144
NCAM1 neural cell adhesion molecule 1 0.322779
EPHA7 EPH receptor A7 0.32205
CTF1 cardiotrophin 1 0.321685
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.320956
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.319498
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.317679
TRIM3 tripartite motif containing 3 0.316588
SCN7A sodium channel, voltage gated, type VII alpha subunit 0.316224
TUBA8 tubulin, alpha 8 0.313683
DCTN1 dynactin 1 0.31332
TMEM30A transmembrane protein 30A 0.31187
PSENEN presenilin enhancer gamma secretase subunit 0.310783
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.308251
SHH sonic hedgehog 0.307528
STX12 syntaxin 12 0.307167
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.307167
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.306805
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.306444
DGKZ diacylglycerol kinase, zeta 0.305722
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.305722
GORAB golgin, RAB6-interacting 0.30464
HDAC3 histone deacetylase 3 0.30464
MCF2L MCF.2 cell line derived transforming sequence-like 0.304279
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.304279
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.303919
PPP4C protein phosphatase 4, catalytic subunit 0.303198
ZHX2 zinc fingers and homeoboxes 2 0.303198
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.302838
EZR ezrin 0.301398
ACTB actin, beta 0.301398
FN1 fibronectin 1 0.301039
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.30032
SH2B2 SH2B adaptor protein 2 0.29996
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.29996
LMNB2 lamin B2 0.299242
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 0.299242
ZDHHC8 zinc finger, DHHC-type containing 8 0.298883
SNX17 sorting nexin 17 0.297806
HDAC2 histone deacetylase 2 0.29673
UNC50 unc-50 homolog (C. elegans) 0.295297
MCF2 MCF.2 cell line derived transforming sequence 0.295297
DUSP1 dual specificity phosphatase 1 0.294223
NEURL1 neuralized E3 ubiquitin protein ligase 1 0.293866
NLRP1 NLR family, pyrin domain containing 1 0.293508
CSK c-src tyrosine kinase 0.293508
TIMP3 TIMP metallopeptidase inhibitor 3 0.290652
HMGB1 high mobility group box 1 0.289939
NLGN2 neuroligin 2 0.28887
GHRL ghrelin/obestatin prepropeptide 0.28887
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.288514
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.288158
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.288158
TAT tyrosine aminotransferase 0.288158
CTSS cathepsin S 0.287803
FOXP2 forkhead box P2 0.287803
ADORA2A adenosine A2a receptor 0.287803
DSCAML1 Down syndrome cell adhesion molecule like 1 0.287092
DRD2 dopamine receptor D2 0.286736
HIST1H1C histone cluster 1, H1c 0.286026
TMEM2 transmembrane protein 2 0.285671
NRF1 nuclear respiratory factor 1 0.285316
MGLL monoglyceride lipase 0.284962
RRAS related RAS viral (r-ras) oncogene homolog 0.284962
ACTG1 actin gamma 1 0.284253
SIRT6 sirtuin 6 0.283545
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.283545
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.281776
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.281423
TJP1 tight junction protein 1 0.281423
APAF1 apoptotic peptidase activating factor 1 0.280717
NPAS4 neuronal PAS domain protein 4 0.280364
HAP1 huntingtin-associated protein 1 0.279659
ARHGAP32 Rho GTPase activating protein 32 0.279659
CLCN4 chloride channel, voltage-sensitive 4 0.279307
CNTN6 contactin 6 0.278955
LIMK1 LIM domain kinase 1 0.278603
GABARAP GABA(A) receptor-associated protein 0.2779
HIST2H2AC histone cluster 2, H2ac 0.2779
MME membrane metallo-endopeptidase 0.2779
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.277549
HIST2H2AA4 histone cluster 2, H2aa4 0.277197
HIST2H2AA3 histone cluster 2, H2aa3 0.277197
SDCCAG8 serologically defined colon cancer antigen 8 0.276145
DRAXIN dorsal inhibitory axon guidance protein 0.275794
EPOR erythropoietin receptor 0.275794
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.274394
ADAP1 ArfGAP with dual PH domains 1 0.272997
BBC3 BCL2 binding component 3 0.271952
NDN necdin, melanoma antigen (MAGE) family member 0.271604
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.270561
GJA1 gap junction protein, alpha 1, 43kDa 0.269867
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 0.269521
PLXND1 plexin D1 0.269521
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.268482
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.268482
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 0.268137
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.268137
SYT12 synaptotagmin XII 0.267102
TMEM106B transmembrane protein 106B 0.267102
ZNF224 zinc finger protein 224 0.265725
NEUROD2 neuronal differentiation 2 0.264696
TXN thioredoxin 0.264696
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.264011
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 0.261284
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.260945
JPH3 junctophilin 3 0.260945
FAIM Fas apoptotic inhibitory molecule 0.260606
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.260606
E2F1 E2F transcription factor 1 0.260606
CABP5 calcium binding protein 5 0.260606
IRF3 interferon regulatory factor 3 0.259929
FLRT2 fibronectin leucine rich transmembrane protein 2 0.259254
ERP29 endoplasmic reticulum protein 29 0.258917
ARRB1 arrestin, beta 1 0.258243
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.258243
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.257907
RTN4RL1 reticulon 4 receptor-like 1 0.257572
ALOX12 arachidonate 12-lipoxygenase 0.256902
UNC5C unc-5 homolog C (C. elegans) 0.256568
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.256568
NOS3 nitric oxide synthase 3 (endothelial cell) 0.256234
TNR tenascin R 0.2559
SDF4 stromal cell derived factor 4 0.255234
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.254902
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.25457
IL6 interleukin 6 0.254239
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.253248
DYM dymeclin 0.252261
HIST1H1B histone cluster 1, H1b 0.251934
SEC24D SEC24 family member D 0.251934
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.251606
CLU clusterin 0.251279
PRIMA1 proline rich membrane anchor 1 0.251279
CLN3 ceroid-lipofuscinosis, neuronal 3 0.250953
CDK12 cyclin-dependent kinase 12 0.250627
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.250627
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.249977
SDC3 syndecan 3 0.249977
H2AFX H2A histone family, member X 0.248361
PLSCR3 phospholipid scramblase 3 0.248361
CXXC5 CXXC finger protein 5 0.24804
SNAP23 synaptosomal-associated protein, 23kDa 0.247719
UFM1 ubiquitin-fold modifier 1 0.247399
BMP7 bone morphogenetic protein 7 0.246442
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.246124
SLC38A1 solute carrier family 38, member 1 0.244232
GSX2 GS homeobox 2 0.242983
TRIM9 tripartite motif containing 9 0.242363
EFNA3 ephrin-A3 0.242363
EFNA1 ephrin-A1 0.241132
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.240826
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.24052
FAM107A family with sequence similarity 107, member A 0.239007
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.238108
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.23781
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.236921
HSPA8 heat shock 70kDa protein 8 0.236627
MVD mevalonate (diphospho) decarboxylase 0.236332
DMD dystrophin 0.23604
SRSF2 serine/arginine-rich splicing factor 2 0.235167
RPS6 ribosomal protein S6 0.234878
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.23459
CRYAB crystallin, alpha B 0.233731
CALHM1 calcium homeostasis modulator 1 0.233446
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 0.233162
STX1A syntaxin 1A (brain) 0.23176
SCAMP1 secretory carrier membrane protein 1 0.230382
CPE carboxypeptidase E 0.23011
PDE4D phosphodiesterase 4D, cAMP-specific 0.229032
SSTR3 somatostatin receptor 3 0.228764
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.228234
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.227707
SNTG1 syntrophin, gamma 1 0.227186
PRDX2 peroxiredoxin 2 0.226411
PLG plasminogen 0.226155
SPTBN1 spectrin, beta, non-erythrocytic 1 0.2259
CNTN1 contactin 1 0.2259
SPAG9 sperm associated antigen 9 0.225144
ESR2 estrogen receptor 2 (ER beta) 0.225144
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.224893
MMP9 matrix metallopeptidase 9 0.224645
TF transferrin 0.222699
CORO1B coronin, actin binding protein, 1B 0.22246
BSN bassoon presynaptic cytomatrix protein 0.222224
LGI3 leucine-rich repeat LGI family, member 3 0.221989
GUCY2C guanylate cyclase 2C 0.221989
CXCR4 chemokine (C-X-C motif) receptor 4 0.221521
RYK receptor-like tyrosine kinase 0.221291
DTNA dystrobrevin, alpha 0.221291
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.220604
NPR1 natriuretic peptide receptor 1 0.220604
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.220604
XBP1 X-box binding protein 1 0.220152
SC5D sterol-C5-desaturase 0.219707
LDB1 LIM domain binding 1 0.219707
NAMPT nicotinamide phosphoribosyltransferase 0.219485
OMA1 OMA1 zinc metallopeptidase 0.219485
GHSR growth hormone secretagogue receptor 0.219485
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.219485
EGR2 early growth response 2 0.219047
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.21883
STARD6 StAR-related lipid transfer (START) domain containing 6 0.218613
TYRO3 TYRO3 protein tyrosine kinase 0.218186
UBE3A ubiquitin protein ligase E3A 0.217346
SCN2A sodium channel, voltage gated, type II alpha subunit 0.21673
HES1 hes family bHLH transcription factor 1 0.215928
NALCN sodium leak channel, non selective 0.21573
CYTH1 cytohesin 1 0.21573
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.21573
UNC5D unc-5 homolog D (C. elegans) 0.21573
GPR45 G protein-coupled receptor 45 0.215147
ADAM17 ADAM metallopeptidase domain 17 0.214954
EN2 engrailed homeobox 2 0.214954
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.214765
SYN2 synapsin II 0.214388
CABIN1 calcineurin binding protein 1 0.214202
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.214202
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.214017
FGF11 fibroblast growth factor 11 0.213833
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.21365
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.213291
CRH corticotropin releasing hormone 0.213112