ceramide signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description Ceramide signaling can act as a lipid second messenger or as a mediator of various cellular signaling pathways by promoting receptor clustering. The pathway plays important roles in apoptosis. (Pathway Ontology, PW_0000961)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_ceramidePathway
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Genes

33 proteins participating in the ceramide signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
BAD BCL2-associated agonist of cell death
BAG4 BCL2-associated athanogene 4
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BIRC3 baculoviral IAP repeat containing 3
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CYCS cytochrome c, somatic
FADD Fas (TNFRSF6)-associated via death domain
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
KSR1 kinase suppressor of ras 1
MADD MAP-kinase activating death domain
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2