cephaeline-4651 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the cephaeline-4651 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL14 ADP-ribosylation factor-like 14
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
C17ORF53 chromosome 17 open reading frame 53
CCNL1 cyclin L1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CIDEC cell death-inducing DFFA-like effector c
CLK4 CDC-like kinase 4
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DMBT1 deleted in malignant brain tumors 1
DNMBP dynamin binding protein
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EFNA1 ephrin-A1
EGR1 early growth response 1
EGR2 early growth response 2
FCMR Fc fragment of IgM receptor
FOSL2 FOS-like antigen 2
FRMD4B FERM domain containing 4B
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
HES1 hes family bHLH transcription factor 1
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AC histone cluster 1, H2ac
HIST1H4C histone cluster 1, H4c
ICAM1 intercellular adhesion molecule 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL11 interleukin 11
IL1A interleukin 1, alpha
IL24 interleukin 24
IL6 interleukin 6
ING3 inhibitor of growth family, member 3
IRF1 interferon regulatory factor 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LIF leukemia inhibitory factor
LRP5L low density lipoprotein receptor-related protein 5-like
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MT1F metallothionein 1F
MT1M metallothionein 1M
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
OVGP1 oviductal glycoprotein 1, 120kDa
PDE4B phosphodiesterase 4B, cAMP-specific
PER1 period circadian clock 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RABGGTB Rab geranylgeranyltransferase, beta subunit
RHOB ras homolog family member B
RIPK4 receptor-interacting serine-threonine kinase 4
RND1 Rho family GTPase 1
SCAND2P SCAN domain containing 2 pseudogene
SCG5 secretogranin V
SFPQ splicing factor proline/glutamine-rich
SLC16A6 solute carrier family 16, member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAI2 snail family zinc finger 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC2 stanniocalcin 2
STX1A syntaxin 1A (brain)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53 tumor protein p53
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ZFP36 ZFP36 ring finger protein
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF16 zinc finger protein 16
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF419 zinc finger protein 419
ZNF44 zinc finger protein 44
ZNF442 zinc finger protein 442
ZNF606 zinc finger protein 606
ZNF671 zinc finger protein 671

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY6 adenylate cyclase 6
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AIDA axin interactor, dorsalization associated
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANOS1 anosmin 1
ARHGAP19 Rho GTPase activating protein 19
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C12ORF49 chromosome 12 open reading frame 49
C5ORF30 chromosome 5 open reading frame 30
CCDC88C coiled-coil domain containing 88C
CCNE2 cyclin E2
CD302 CD302 molecule
CERK ceramide kinase
CGREF1 cell growth regulator with EF-hand domain 1
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DCAF4 DDB1 and CUL4 associated factor 4
DCP2 decapping mRNA 2
DENND1B DENN/MADD domain containing 1B
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EML4 echinoderm microtubule associated protein like 4
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOC5 exocyst complex component 5
FAM168B family with sequence similarity 168, member B
FAM172A family with sequence similarity 172, member A
FAM20B family with sequence similarity 20, member B
FAM3C family with sequence similarity 3, member C
FAM69A family with sequence similarity 69, member A
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
FZD8 frizzled class receptor 8
GID4 GID complex subunit 4
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HDAC4 histone deacetylase 4
HELLS helicase, lymphoid-specific
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
IFI30 interferon, gamma-inducible protein 30
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA6 integrin, alpha 6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD7 potassium channel tetramerization domain containing 7
KIAA1462 KIAA1462
LBR lamin B receptor
LEMD3 LEM domain containing 3
LMNB1 lamin B1
LOC100127972 uncharacterized LOC100127972
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAT2A methionine adenosyltransferase II, alpha
MFSD6 major facilitator superfamily domain containing 6
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NOL12 nucleolar protein 12
OSMR oncostatin M receptor
PAPD7 PAP associated domain containing 7
PDZD8 PDZ domain containing 8
PLCD1 phospholipase C, delta 1
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPT2 palmitoyl-protein thioesterase 2
PRKX protein kinase, X-linked
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGFR prostaglandin F receptor (FP)
PTPRS protein tyrosine phosphatase, receptor type, S
RUFY2 RUN and FYVE domain containing 2
SCAI suppressor of cancer cell invasion
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERINC5 serine incorporator 5
SETD8 SET domain containing (lysine methyltransferase) 8
SIAH2 siah E3 ubiquitin protein ligase 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC38A1 solute carrier family 38, member 1
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
SNX6 sorting nexin 6
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STARD3 StAR-related lipid transfer (START) domain containing 3
TBC1D12 TBC1 domain family, member 12
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THOP1 thimet oligopeptidase 1
TMEM30A transmembrane protein 30A
UNC119B unc-119 homolog B (C. elegans)
ZBED1 zinc finger, BED-type containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZMAT3 zinc finger, matrin-type 3
ZNF106 zinc finger protein 106