cellular metachromasia Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Metachromasia (also known as metachromacy) is a characteristic color change which certain aniline dyes exhibit when bound to particular substances or when concentrated in solution. For example, the basic dye toluidine blue becomes distinctly pink when bound to cartilage matrix. In the sense used here, the metachromasia refers to a change in color not observed with normal tissues, anomalous staining with the cationic dyes toluidine blue O and Alcian blue resulting from excessive amounts of the polyanionic glycosaminoglycans. (Human Phenotype Ontology, HP_0003653)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0003653
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2 genes associated with the cellular metachromasia phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
GNS glucosamine (N-acetyl)-6-sulfatase
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase