cell-substrate junction Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cell junction that forms a connection between a cell and the extracellular matrix. (Gene Ontology, GO_0030055)
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Genes

738 proteins co-occuring with the cell-substrate junction cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PXN paxillin 3.6845
VCL vinculin 3.07121
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.7171
FN1 fibronectin 1 2.6524
PTK2 protein tyrosine kinase 2 2.45286
COL17A1 collagen, type XVII, alpha 1 2.31925
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.12749
PTK2B protein tyrosine kinase 2 beta 1.9685
ILK integrin-linked kinase 1.9091
ZYX zyxin 1.89939
BCAR1 breast cancer anti-estrogen resistance 1 1.88417
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.81377
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.80707
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.75788
SEBOX SEBOX homeobox 1.75403
TNS1 tensin 1 1.74892
ITGB4 integrin, beta 4 1.68055
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.67933
CDC42 cell division cycle 42 1.62827
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.48984
VASP vasodilator-stimulated phosphoprotein 1.47118
SDC4 syndecan 4 1.46608
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.42429
FERMT1 fermitin family member 1 1.40298
ITGB6 integrin, beta 6 1.39016
CSK c-src tyrosine kinase 1.38738
GRB2 growth factor receptor-bound protein 2 1.3835
MMP2 matrix metallopeptidase 2 1.37409
ITGB7 integrin, beta 7 1.34065
ITGB8 integrin, beta 8 1.33902
FYN FYN proto-oncogene, Src family tyrosine kinase 1.32762
ITGA6 integrin, alpha 6 1.326
TLN1 talin 1 1.30604
FERMT2 fermitin family member 2 1.30497
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.28997
MMP9 matrix metallopeptidase 9 1.28943
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.28729
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.27877
GRB7 growth factor receptor-bound protein 7 1.2497
COL7A1 collagen, type VII, alpha 1 1.23661
EGFR epidermal growth factor receptor 1.22776
PTPRD protein tyrosine phosphatase, receptor type, D 1.22049
PARVA parvin, alpha 1.21531
DLC1 DLC1 Rho GTPase activating protein 1.21325
CTTN cortactin 1.21066
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.20344
DNM2 dynamin 2 1.19108
ARHGAP35 Rho GTPase activating protein 35 1.18184
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.17876
PTEN phosphatase and tensin homolog 1.17671
LAMB3 laminin, beta 3 1.14392
JUN jun proto-oncogene 1.11939
TNC tenascin C 1.11735
TRIP6 thyroid hormone receptor interactor 6 1.1148
TNS2 tensin 2 1.0873
LAMB2 laminin, beta 2 (laminin S) 1.08526
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.08069
GRP gastrin-releasing peptide 1.07308
LAMC2 laminin, gamma 2 1.07207
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.05842
TNS4 tensin 4 1.0569
PARVB parvin, beta 1.05539
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.04934
MAPK3 mitogen-activated protein kinase 3 1.04733
BCAR3 breast cancer anti-estrogen resistance 3 1.04431
LPP LIM domain containing preferred translocation partner in lipoma 1.04331
PLAU plasminogen activator, urokinase 1.0418
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.03529
MSN moesin 1.02979
RB1CC1 RB1-inducible coiled-coil 1 1.01684
CD44 CD44 molecule (Indian blood group) 1.00892
EZR ezrin 0.999068
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.998086
THBS1 thrombospondin 1 0.990736
TGFB1 transforming growth factor, beta 1 0.988294
ITGAV integrin, alpha V 0.982932
SPP1 secreted phosphoprotein 1 0.982446
LHX3 LIM homeobox 3 0.981959
DOCK1 dedicator of cytokinesis 1 0.966956
CAV1 caveolin 1, caveolae protein, 22kDa 0.966956
PKN1 protein kinase N1 0.959748
RDX radixin 0.952096
MET MET proto-oncogene, receptor tyrosine kinase 0.934544
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.931245
EPHA2 EPH receptor A2 0.927013
LPXN leupaxin 0.901353
VEGFA vascular endothelial growth factor A 0.890245
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.890245
LASP1 LIM and SH3 protein 1 0.889783
KDR kinase insert domain receptor 0.877791
ARHGAP1 Rho GTPase activating protein 1 0.87733
DST dystonin 0.87733
MYLK myosin light chain kinase 0.873186
STARD13 StAR-related lipid transfer (START) domain containing 13 0.86077
IGF1 insulin-like growth factor 1 (somatomedin C) 0.860311
ZHX2 zinc fingers and homeoboxes 2 0.852961
CCND1 cyclin D1 0.850206
ERBB2 erb-b2 receptor tyrosine kinase 2 0.846532
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.845614
SAR1A secretion associated, Ras related GTPase 1A 0.845155
FERMT3 fermitin family member 3 0.843778
LIMS2 LIM and senescent cell antigen-like domains 2 0.839187
LIMS3 LIM and senescent cell antigen-like domains 3 0.829089
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.823123
RHOB ras homolog family member B 0.817616
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.815781
RAP2B RAP2B, member of RAS oncogene family 0.81257
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.808441
ARF3 ADP-ribosylation factor 3 0.803855
ARHGAP18 Rho GTPase activating protein 18 0.803396
FGF2 fibroblast growth factor 2 (basic) 0.801104
RAB1B RAB1B, member RAS oncogene family 0.800645
CIB1 calcium and integrin binding 1 (calmyrin) 0.800187
DMD dystrophin 0.797895
LYN LYN proto-oncogene, Src family tyrosine kinase 0.79652
CXCL12 chemokine (C-X-C motif) ligand 12 0.785986
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.785071
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.785071
PALLD palladin, cytoskeletal associated protein 0.784156
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.781869
TP53 tumor protein p53 0.770451
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.764072
MAPK8 mitogen-activated protein kinase 8 0.763617
PLEC plectin 0.755437
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.75453
IGF1R insulin-like growth factor 1 receptor 0.748189
CDH5 cadherin 5, type 2 (vascular endothelium) 0.736464
FLNA filamin A, alpha 0.733319
ACTN4 actinin, alpha 4 0.731973
ZFYVE21 zinc finger, FYVE domain containing 21 0.725705
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.724812
DSP desmoplakin 0.711908
MAPK14 mitogen-activated protein kinase 14 0.699983
LAMA3 laminin, alpha 3 0.699103
CD151 CD151 molecule (Raph blood group) 0.698663
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.698223
NCK2 NCK adaptor protein 2 0.695148
GRPR gastrin-releasing peptide receptor 0.690326
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.687264
MAPK1 mitogen-activated protein kinase 1 0.683335
PFN1 profilin 1 0.682463
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.678978
EFNA1 ephrin-A1 0.678543
TNS3 tensin 3 0.678543
PARVG parvin, gamma 0.678543
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.677238
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.670292
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.668126
MAPK11 mitogen-activated protein kinase 11 0.668126
SYK spleen tyrosine kinase 0.664664
FLT4 fms-related tyrosine kinase 4 0.6638
PTS 6-pyruvoyltetrahydropterin synthase 0.65388
ICAM1 intercellular adhesion molecule 1 0.650439
PLEK pleckstrin 0.650439
SORBS1 sorbin and SH3 domain containing 1 0.64958
JAK2 Janus kinase 2 0.647003
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.646574
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.644858
TGM2 transglutaminase 2 0.644429
PLG plasminogen 0.63715
VCAM1 vascular cell adhesion molecule 1 0.635013
FOS FBJ murine osteosarcoma viral oncogene homolog 0.633732
ITGA7 integrin, alpha 7 0.633732
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.633305
IRS1 insulin receptor substrate 1 0.633305
HRAS Harvey rat sarcoma viral oncogene homolog 0.631598
IBSP integrin-binding sialoprotein 0.630318
SDC1 syndecan 1 0.627761
CDKN2A cyclin-dependent kinase inhibitor 2A 0.624781
KLF8 Kruppel-like factor 8 0.62393
GSN gelsolin 0.622654
KRT3 keratin 3, type II 0.614165
ZNF384 zinc finger protein 384 0.611625
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.611625
PFN2 profilin 2 0.609932
TLN2 talin 2 0.598538
VAV2 vav 2 guanine nucleotide exchange factor 0.594753
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.594753
CTGF connective tissue growth factor 0.589295
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.587199
PFN4 profilin family, member 4 0.583431
FLT1 fms-related tyrosine kinase 1 0.58134
ITGB1BP1 integrin beta 1 binding protein 1 0.580086
TNF tumor necrosis factor 0.574244
LIMS1 LIM and senescent cell antigen-like domains 1 0.573411
RSU1 Ras suppressor protein 1 0.569248
INPPL1 inositol polyphosphate phosphatase-like 1 0.567169
BGLAP bone gamma-carboxyglutamate (gla) protein 0.566754
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.563432
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.563017
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.560114
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.558042
TM4SF5 transmembrane 4 L six family member 5 0.551838
GRB14 growth factor receptor-bound protein 14 0.551425
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.550186
CALR calreticulin 0.548535
INS insulin 0.546885
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.544
ERBB3 erb-b2 receptor tyrosine kinase 3 0.543587
SMAD2 SMAD family member 2 0.542764
CD79A CD79a molecule, immunoglobulin-associated alpha 0.53906
FLNC filamin C, gamma 0.533309
FSCN1 fascin actin-bundling protein 1 0.531668
IVL involucrin 0.530028
EDN1 endothelin 1 0.527979
NID1 nidogen 1 0.525113
CTNND1 catenin (cadherin-associated protein), delta 1 0.524704
UTRN utrophin 0.524294
SORBS2 sorbin and SH3 domain containing 2 0.523885
CD9 CD9 molecule 0.523476
CDK20 cyclin-dependent kinase 20 0.522659
TES testin LIM domain protein 0.521432
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.516532
NPHP1 nephronophthisis 1 (juvenile) 0.513677
CAST calpastatin 0.51327
EFS embryonal Fyn-associated substrate 0.512862
TJP1 tight junction protein 1 0.512455
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.510011
SDC2 syndecan 2 0.509197
ESR1 estrogen receptor 1 0.50879
TPM1 tropomyosin 1 (alpha) 0.505537
F2R coagulation factor II (thrombin) receptor 0.504318
SHB Src homology 2 domain containing adaptor protein B 0.504318
LIM2 lens intrinsic membrane protein 2, 19kDa 0.502693
CALD1 caldesmon 1 0.502693
ALPPL2 alkaline phosphatase, placental-like 2 0.499042
ALPL alkaline phosphatase, liver/bone/kidney 0.498636
ALPP alkaline phosphatase, placental 0.498231
NEBL nebulette 0.497015
TYRO3 TYRO3 protein tyrosine kinase 0.49661
NRP1 neuropilin 1 0.495395
GSTA1 glutathione S-transferase alpha 1 0.49499
WASL Wiskott-Aldrich syndrome-like 0.492561
MACF1 microtubule-actin crosslinking factor 1 0.492157
LIMK1 LIM domain kinase 1 0.486096
GSTA3 glutathione S-transferase alpha 3 0.486096
VAV1 vav 1 guanine nucleotide exchange factor 0.484886
GSTA2 glutathione S-transferase alpha 2 0.484079
GSTA4 glutathione S-transferase alpha 4 0.484079
KNG1 kininogen 1 0.483273
ARHGAP31 Rho GTPase activating protein 31 0.482467
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.482064
PGM5 phosphoglucomutase 5 0.479647
MMP13 matrix metallopeptidase 13 0.474018
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.473617
CYR61 cysteine-rich, angiogenic inducer, 61 0.473215
RUNX2 runt-related transcription factor 2 0.473215
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.472011
TIMP2 TIMP metallopeptidase inhibitor 2 0.470807
FOCAD focadhesin 0.469203
PLCG1 phospholipase C, gamma 1 0.464397
MMP7 matrix metallopeptidase 7 0.462798
FGF1 fibroblast growth factor 1 (acidic) 0.461199
LCK LCK proto-oncogene, Src family tyrosine kinase 0.456809
FHL2 four and a half LIM domains 2 0.456012
INSR insulin receptor 0.456012
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.455214
EPHB4 EPH receptor B4 0.454418
MMP1 matrix metallopeptidase 1 0.453223
ALB albumin 0.452029
RHOJ ras homolog family member J 0.451631
SYNM synemin, intermediate filament protein 0.447259
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.446069
MARCKS myristoylated alanine-rich protein kinase C substrate 0.443689
EGFL6 EGF-like-domain, multiple 6 0.4425
FBN1 fibrillin 1 0.442104
COL22A1 collagen, type XXII, alpha 1 0.440124
CAPN2 calpain 2, (m/II) large subunit 0.438937
PI3 peptidase inhibitor 3, skin-derived 0.438146
TIMP1 TIMP metallopeptidase inhibitor 1 0.434985
DSG3 desmoglein 3 0.431829
RRAS related RAS viral (r-ras) oncogene homolog 0.431041
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.430647
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 0.430253
MARK2 MAP/microtubule affinity-regulating kinase 2 0.427891
AJUBA ajuba LIM protein 0.425924
ZER1 zyg-11 related, cell cycle regulator 0.424745
BMX BMX non-receptor tyrosine kinase 0.424353
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 0.422389
SMAD3 SMAD family member 3 0.421604
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.421212
ACTB actin, beta 0.418468
XIRP2 xin actin binding repeat containing 2 0.41612
GRB10 growth factor receptor-bound protein 10 0.414555
EPHB2 EPH receptor B2 0.413382
COL18A1 collagen, type XVIII, alpha 1 0.412992
EPHA1 EPH receptor A1 0.412601
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.412601
ACTA1 actin, alpha 1, skeletal muscle 0.404415
NET1 neuroepithelial cell transforming 1 0.404026
CXCR4 chemokine (C-X-C motif) receptor 4 0.402081
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.401304
PTPRH protein tyrosine phosphatase, receptor type, H 0.400139
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.397811
SDCBP syndecan binding protein (syntenin) 0.395485
RND3 Rho family GTPase 3 0.395098
EPB41 erythrocyte membrane protein band 4.1 0.395098
CCKBR cholecystokinin B receptor 0.39471
FHL1 four and a half LIM domains 1 0.388909
GP6 glycoprotein VI (platelet) 0.388523
DSG1 desmoglein 1 0.386208
ITGB5 integrin, beta 5 0.385822
MYLK3 myosin light chain kinase 3 0.38428
MMP3 matrix metallopeptidase 3 0.383509
PARP1 poly (ADP-ribose) polymerase 1 0.382739
TTC9 tetratricopeptide repeat domain 9 0.382739
NEB nebulin 0.382354
NTN1 netrin 1 0.381584
CFL1 cofilin 1 (non-muscle) 0.381199
S100A4 S100 calcium binding protein A4 0.380429
KRT14 keratin 14, type I 0.380045
NPS neuropeptide S 0.378507
MIR197 microRNA 197 0.37697
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.375818
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.374666
PEPD peptidase D 0.372749
ACTG1 actin gamma 1 0.372366
PRKD3 protein kinase D3 0.371599
NOS3 nitric oxide synthase 3 (endothelial cell) 0.371216
NOV nephroblastoma overexpressed 0.368153
ACTN1 actinin, alpha 1 0.368153
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.367006
RET ret proto-oncogene 0.365095
ANKRD28 ankyrin repeat domain 28 0.365095
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.364713
GSK3B glycogen synthase kinase 3 beta 0.362422
JUP junction plakoglobin 0.361659
DIXDC1 DIX domain containing 1 0.35899
LOX lysyl oxidase 0.357847
EGFL7 EGF-like-domain, multiple 7 0.357467
IL1B interleukin 1, beta 0.356324
STK4 serine/threonine kinase 4 0.354422
LIMD1 LIM domains containing 1 0.354042
NEO1 neogenin 1 0.354042
LAMA5 laminin, alpha 5 0.354042
PRPF4B pre-mRNA processing factor 4B 0.352142
THY1 Thy-1 cell surface antigen 0.349863
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.349484
MYOCD myocardin 0.348725
CD82 CD82 molecule 0.347967
GJA1 gap junction protein, alpha 1, 43kDa 0.34645
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.345692
TMSB4X thymosin beta 4, X-linked 0.345314
SIRPA signal-regulatory protein alpha 0.344935
CCR1 chemokine (C-C motif) receptor 1 0.344178
TLK1 tousled-like kinase 1 0.344178
GAST gastrin 0.343799
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.343421
ATG13 autophagy related 13 0.340773
ITGA1 integrin, alpha 1 0.338128
ITGA8 integrin, alpha 8 0.337751
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.336619
ESAM endothelial cell adhesion molecule 0.336619
BHLHE22 basic helix-loop-helix family, member e22 0.334733
WNT5A wingless-type MMTV integration site family, member 5A 0.333602
RAP1A RAP1A, member of RAS oncogene family 0.333225
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.332848
ISL1 ISL LIM homeobox 1 0.331342
TESK1 testis-specific kinase 1 0.330589
PDCD10 programmed cell death 10 0.330213
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.329084
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.329084
NF2 neurofibromin 2 (merlin) 0.329084
EVL Enah/Vasp-like 0.328332
XIRP1 xin actin binding repeat containing 1 0.325702
PHACTR4 phosphatase and actin regulator 4 0.325327
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.324576
RABL3 RAB, member of RAS oncogene family-like 3 0.321201
ANK1 ankyrin 1, erythrocytic 0.319328
FGR FGR proto-oncogene, Src family tyrosine kinase 0.318579
NELL1 NEL-like 1 (chicken) 0.318205
RTKN rhotekin 0.317456
BMP2 bone morphogenetic protein 2 0.31596
LAMA2 laminin, alpha 2 0.315586
RAVER1 ribonucleoprotein, PTB-binding 1 0.315212
STK25 serine/threonine kinase 25 0.312971
DAP death-associated protein 0.310358
RHOA ras homolog family member A 0.310358
EPS8 epidermal growth factor receptor pathway substrate 8 0.309986
ULK1 unc-51 like autophagy activating kinase 1 0.309613
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.30924
PDGFB platelet-derived growth factor beta polypeptide 0.308494
COL1A1 collagen, type I, alpha 1 0.308122
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.305143
OCLN occludin 0.304399
MAPK7 mitogen-activated protein kinase 7 0.303655
MAP2K1 mitogen-activated protein kinase kinase 1 0.302168
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.300682
HCK HCK proto-oncogene, Src family tyrosine kinase 0.300682
CXCL8 chemokine (C-X-C motif) ligand 8 0.297342
FMN1 formin 1 0.296601
SRCIN1 SRC kinase signaling inhibitor 1 0.29586
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.295489
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.294748
ANGPT2 angiopoietin 2 0.293637
ANXA5 annexin A5 0.292897
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.291047
RHOBTB2 Rho-related BTB domain containing 2 0.290308
FGF7 fibroblast growth factor 7 0.290308
DDR1 discoidin domain receptor tyrosine kinase 1 0.290308
NRP2 neuropilin 2 0.289938
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.289569
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.289199
COL13A1 collagen, type XIII, alpha 1 0.289199
CD47 CD47 molecule 0.288829
LGI3 leucine-rich repeat LGI family, member 3 0.287721
ADAM12 ADAM metallopeptidase domain 12 0.287352
KRAS Kirsten rat sarcoma viral oncogene homolog 0.287352
MIR95 microRNA 95 0.286245
MUC4 mucin 4, cell surface associated 0.285507
ARF6 ADP-ribosylation factor 6 0.283295
NOX1 NADPH oxidase 1 0.282558
FLNB filamin B, beta 0.281821
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.279245
TYK2 tyrosine kinase 2 0.278141
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.277406
FLII flightless I homolog (Drosophila) 0.276671
WAS Wiskott-Aldrich syndrome 0.275936
SCARA5 scavenger receptor class A, member 5 0.275569
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.273734
ARHGAP10 Rho GTPase activating protein 10 0.273
TNK2 tyrosine kinase, non-receptor, 2 0.273
NGF nerve growth factor (beta polypeptide) 0.2708
AXL AXL receptor tyrosine kinase 0.270068
SOS1 son of sevenless homolog 1 (Drosophila) 0.269701
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.267139
MCF2 MCF.2 cell line derived transforming sequence 0.267139
TIAM1 T-cell lymphoma invasion and metastasis 1 0.266042
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.264581
FBLN2 fibulin 2 0.264581
VWF von Willebrand factor 0.263485
CDK2 cyclin-dependent kinase 2 0.260931
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.260202
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.259837
FGFR2 fibroblast growth factor receptor 2 0.259837
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.259837
BSG basigin (Ok blood group) 0.258745
EVPL envoplakin 0.258745
MERTK MER proto-oncogene, tyrosine kinase 0.257289
DCN decorin 0.257289
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.256197
BST1 bone marrow stromal cell antigen 1 0.256197
PODXL podocalyxin-like 0.256197
LGALS3 lectin, galactoside-binding, soluble, 3 0.256197
IL32 interleukin 32 0.254017
GFAP glial fibrillary acidic protein 0.251476
LOXL2 lysyl oxidase-like 2 0.251476
CSPG4 chondroitin sulfate proteoglycan 4 0.251114
CDK4 cyclin-dependent kinase 4 0.248216
HBEGF heparin-binding EGF-like growth factor 0.247854
FLG filaggrin 0.247492
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.246407
AR androgen receptor 0.245685
CDCP1 CUB domain containing protein 1 0.245323
LMO7 LIM domain 7 0.243519
EPHA3 EPH receptor A3 0.243158
MYOM1 myomesin 1 0.242797
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.242437
MAPK9 mitogen-activated protein kinase 9 0.240996
IQGAP1 IQ motif containing GTPase activating protein 1 0.238837
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.238119
EFNB2 ephrin-B2 0.235249
MARK3 MAP/microtubule affinity-regulating kinase 3 0.235249
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.233817
LPAR2 lysophosphatidic acid receptor 2 0.233459
IRS2 insulin receptor substrate 2 0.233101
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.233101
CCNB1 cyclin B1 0.232744
PLAT plasminogen activator, tissue 0.230958
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.230958
STARD8 StAR-related lipid transfer (START) domain containing 8 0.230958
CD34 CD34 molecule 0.230245
MIR15B microRNA 15b 0.229888
RPSA ribosomal protein SA 0.228819
FBLIM1 filamin binding LIM protein 1 0.227397
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.227397
VCAN versican 0.225976
TMIGD2 transmembrane and immunoglobulin domain containing 2 0.225976
PGR progesterone receptor 0.225976
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.225622
CPNE3 copine III 0.224913
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.224558
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.224558
ANKRD13A ankyrin repeat domain 13A 0.223143
RHOU ras homolog family member U 0.22173
PCNA proliferating cell nuclear antigen 0.221025
CDK5 cyclin-dependent kinase 5 0.221025
BCL2L1 BCL2-like 1 0.218914
BCAM basal cell adhesion molecule (Lutheran blood group) 0.218563
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.218563
BIRC5 baculoviral IAP repeat containing 5 0.218212
HRG histidine-rich glycoprotein 0.218212
ARHGAP30 Rho GTPase activating protein 30 0.217511
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.217511
TENM4 teneurin transmembrane protein 4 0.215412
SLK STE20-like kinase 0.213669
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.213322
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.212627
EPHA5 EPH receptor A5 0.21124
GRAP2 GRB2-related adaptor protein 2 0.210549
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.210203
KRT12 keratin 12, type I 0.210203
PF4 platelet factor 4 0.209858
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.209513
PDLIM2 PDZ and LIM domain 2 (mystique) 0.208825
BAX BCL2-associated X protein 0.208481
EDNRB endothelin receptor type B 0.208137
EPHA4 EPH receptor A4 0.207794
COL6A3 collagen, type VI, alpha 3 0.207108
DES desmin 0.206423
KLHL11 kelch-like family member 11 0.206082
SELE selectin E 0.206082
CRIP2 cysteine-rich protein 2 0.20574
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.205059
RHOD ras homolog family member D 0.204718
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.204378
CAV2 caveolin 2 0.204378
MAP2K7 mitogen-activated protein kinase kinase 7 0.203022
TGFBI transforming growth factor, beta-induced, 68kDa 0.202684
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.202009
LAYN layilin 0.201335
SFTPA2 surfactant protein A2 0.200999
GPR52 G protein-coupled receptor 52 0.200663
AMER2 APC membrane recruitment protein 2 0.200663
FSCN3 fascin actin-bundling protein 3, testicular 0.199993
CTHRC1 collagen triple helix repeat containing 1 0.198325
TNXA tenascin XA (pseudogene) 0.197662
TNXB tenascin XB 0.197662
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.196669
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.196669
GRN granulin 0.196669
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.195353
MIR223 microRNA 223 0.195353
PLK4 polo-like kinase 4 0.194698
ERBB4 erb-b2 receptor tyrosine kinase 4 0.194371
COL3A1 collagen, type III, alpha 1 0.194371
SCRIB scribbled planar cell polarity protein 0.194371
TXNDC9 thioredoxin domain containing 9 0.193719
EFNB3 ephrin-B3 0.193719
ECM1 extracellular matrix protein 1 0.19307
ARF5 ADP-ribosylation factor 5 0.19307
IL6 interleukin 6 0.1921
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.191777
POSTN periostin, osteoblast specific factor 0.190175
ARHGAP11A Rho GTPase activating protein 11A 0.189222
NCKIPSD NCK interacting protein with SH3 domain 0.189222
PPP6C protein phosphatase 6, catalytic subunit 0.188905
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.18859
FSCN2 fascin actin-bundling protein 2, retinal 0.188274
NOX4 NADPH oxidase 4 0.18796
SOCS3 suppressor of cytokine signaling 3 0.184241
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 0.184241
MMP12 matrix metallopeptidase 12 0.184241
NHSL1 NHS-like 1 0.184241
NHSL2 NHS-like 2 0.184241
PPP5C protein phosphatase 5, catalytic subunit 0.184241
DCC DCC netrin 1 receptor 0.183935
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.183328
EPHA7 EPH receptor A7 0.183328
ELANE elastase, neutrophil expressed 0.182723
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.181227
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.180634
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.179459
PLXNC1 plexin C1 0.178299
TIAM2 T-cell lymphoma invasion and metastasis 2 0.178299
EIF4E eukaryotic translation initiation factor 4E 0.177154
PPL periplakin 0.176024
KRT4 keratin 4, type II 0.175745
TESK2 testis-specific kinase 2 0.175188
THSD7A thrombospondin, type I, domain containing 7A 0.174635
ETV4 ets variant 4 0.174635
ANXA2 annexin A2 0.174635
DMTF1 cyclin D binding myb-like transcription factor 1 0.173814
TTN titin 0.173543
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.173543
DUX4L9 double homeobox 4 like 9 0.172735
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.172735
DUX4L4 double homeobox 4 like 4 0.172735
ACHE acetylcholinesterase (Yt blood group) 0.171673
FBLN7 fibulin 7 0.171149
WISP1 WNT1 inducible signaling pathway protein 1 0.170629
SLC16A11 solute carrier family 16, member 11 0.170371
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.170114
CAPNS1 calpain, small subunit 1 0.169604
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.169604
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.169099
ASB2 ankyrin repeat and SOCS box containing 2 0.168598
PNMA6A paraneoplastic Ma antigen family member 6A 0.168101
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.167366
HAS2 hyaluronan synthase 2 0.167366
FGFR3 fibroblast growth factor receptor 3 0.166884
TRIM15 tripartite motif containing 15 0.166643
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.166167
ZDHHC1 zinc finger, DHHC-type containing 1 0.165231
CCL4 chemokine (C-C motif) ligand 4 0.16477
EPHB1 EPH receptor B1 0.164315
AMER3 APC membrane recruitment protein 3 0.164315
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.164089
ATG101 autophagy related 101 0.163865
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.16298
RB1 retinoblastoma 1 0.162763
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.16233
CSRP2 cysteine and glycine-rich protein 2 0.16233
ARF1 ADP-ribosylation factor 1 0.162117
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.161905
RAP1B RAP1B, member of RAS oncogene family 0.161905
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.161905
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.161693
SVIL supervillin 0.160658
TGFB2 transforming growth factor, beta 2 0.160456
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 0.160053
LDB2 LIM domain binding 2 0.159462
PNPLA5 patatin-like phospholipase domain containing 5 0.159462
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.158882
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.158692
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.158692
F11R F11 receptor 0.158692
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.158502
PVR poliovirus receptor 0.158315
SPDEF SAM pointed domain containing ETS transcription factor 0.158129
CDK1 cyclin-dependent kinase 1 0.15776
PARK2 parkin RBR E3 ubiquitin protein ligase 0.15776
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.157039
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.156863
FRK fyn-related Src family tyrosine kinase 0.156688
CDSN corneodesmosin 0.156688
CMA1 chymase 1, mast cell 0.156688
MKX mohawk homeobox 0.137695
CIB2 calcium and integrin binding family member 2 0.135493
GAS2 growth arrest-specific 2 0.135337
EIF6 eukaryotic translation initiation factor 6 0.134458
DSC2 desmocollin 2 0.134428
LOR loricrin 0.134231
VAMP5 vesicle-associated membrane protein 5 0.13417
LAD1 ladinin 1 0.133594
LDB3 LIM domain binding 3 0.133585
DMPK dystrophia myotonica-protein kinase 0.133247
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 0.133196
LAX1 lymphocyte transmembrane adaptor 1 0.133035
MRPL12 mitochondrial ribosomal protein L12 0.132409
SFRP4 secreted frizzled-related protein 4 0.132327
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.132327
JAK1 Janus kinase 1 0.132133
COL5A2 collagen, type V, alpha 2 0.132123
SH2D3C SH2 domain containing 3C 0.132114
PNCK pregnancy up-regulated nonubiquitous CaM kinase 0.132001
CXCR1 chemokine (C-X-C motif) receptor 1 0.131926
TSC2 tuberous sclerosis 2 0.131926
PLXND1 plexin D1 0.131926
LPAR6 lysophosphatidic acid receptor 6 0.131916
ADAM15 ADAM metallopeptidase domain 15 0.131916
MYOT myotilin 0.131329
NES nestin 0.131208
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.130709
DSC3 desmocollin 3 0.130709
MUC21 mucin 21, cell surface associated 0.130527
GPC6 glypican 6 0.130429
EIF1 eukaryotic translation initiation factor 1 0.130243
DSG2 desmoglein 2 0.130031
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.129963
MYOZ1 myozenin 1 0.129895
DUX4L8 double homeobox 4 like 8 0.129895
CADM4 cell adhesion molecule 4 0.129582
AKR1C4 aldo-keto reductase family 1, member C4 0.129333
SNX5 sorting nexin 5 0.129321
BHLHE23 basic helix-loop-helix family, member e23 0.129188
MST1 macrophage stimulating 1 0.129164
SOX18 SRY (sex determining region Y)-box 18 0.128053
ERBB2IP erbb2 interacting protein 0.127768
SACS sacsin molecular chaperone 0.127362
TNMD tenomodulin 0.127263
COL6A2 collagen, type VI, alpha 2 0.127248
SNTA1 syntrophin, alpha 1 0.127219
COMP cartilage oligomeric matrix protein 0.127075
COL14A1 collagen, type XIV, alpha 1 0.12706
ASB14 ankyrin repeat and SOCS box containing 14 0.126913
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.126809
GJB6 gap junction protein, beta 6, 30kDa 0.126415
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.1264
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.126198
PRG4 proteoglycan 4 0.126166
APLF aprataxin and PNKP like factor 0.12596
ITGA9 integrin, alpha 9 0.125847
KRT10 keratin 10, type I 0.125717
THBS4 thrombospondin 4 0.12557
KRT13 keratin 13, type I 0.124607
KRT1 keratin 1, type II 0.124535
KANK1 KN motif and ankyrin repeat domains 1 0.124445
SFN stratifin 0.124152
KRT5 keratin 5, type II 0.124114
MATN3 matrilin 3 0.123946
BNC1 basonuclin 1 0.123889
SCX scleraxis basic helix-loop-helix transcription factor 0.123717
SSPN sarcospan 0.123621
SV2B synaptic vesicle glycoprotein 2B 0.123504
WNT2 wingless-type MMTV integration site family member 2 0.123426
TP63 tumor protein p63 0.123347
LHB luteinizing hormone beta polypeptide 0.122904
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.122552
MALL mal, T-cell differentiation protein-like 0.122468
TMPRSS15 transmembrane protease, serine 15 0.122103
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.121594
GPR83 G protein-coupled receptor 83 0.121594
CLTC clathrin, heavy chain (Hc) 0.121526
IPO7 importin 7 0.121366
CAV3 caveolin 3 0.120804
TFDP3 transcription factor Dp family, member 3 0.120661
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.120441
DSC1 desmocollin 1 0.120319
HOXC8 homeobox C8 0.11984
KRT19 keratin 19, type I 0.119161
COL6A1 collagen, type VI, alpha 1 0.118617
HDAC4 histone deacetylase 4 0.11845
SRRM1 serine/arginine repetitive matrix 1 0.118111
LHX2 LIM homeobox 2 0.117937
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.117675
FGF8 fibroblast growth factor 8 (androgen-induced) 0.117675
HOXA5 homeobox A5 0.117498
CHAT choline O-acetyltransferase 0.117228
PKP3 plakophilin 3 0.117046
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.117016
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.116393
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.116266
PGM1 phosphoglucomutase 1 0.115976
SURF1 surfeit 1 0.11578
LDB1 LIM domain binding 1 0.115348
DDN dendrin 0.115113
IL1A interleukin 1, alpha 0.115078
BCHE butyrylcholinesterase 0.115044
CLCN2 chloride channel, voltage-sensitive 2 0.114906
ADRA1D adrenoceptor alpha 1D 0.114837
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.11399
MYOM2 myomesin 2 0.113881
EREG epiregulin 0.113845
MYOD1 myogenic differentiation 1 0.113589
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.113105
PTPRU protein tyrosine phosphatase, receptor type, U 0.113105
PABPN1 poly(A) binding protein, nuclear 1 0.112991