cell-substrate adherens junction Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An adherens junction which connects a cell to the extracellular matrix. (Gene Ontology, GO_0005924)
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Genes

652 proteins co-occuring with the cell-substrate adherens junction cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PXN paxillin 3.72349
VCL vinculin 3.09047
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.73873
FN1 fibronectin 1 2.64185
PTK2 protein tyrosine kinase 2 2.47601
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.13914
PTK2B protein tyrosine kinase 2 beta 1.98835
ILK integrin-linked kinase 1.92299
ZYX zyxin 1.91882
BCAR1 breast cancer anti-estrogen resistance 1 1.90285
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.82728
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.81983
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.77535
SEBOX SEBOX homeobox 1.7682
TNS1 tensin 1 1.7669
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.67872
CDC42 cell division cycle 42 1.63539
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.49606
VASP vasodilator-stimulated phosphoprotein 1.48023
SDC4 syndecan 4 1.47231
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.43387
FERMT1 fermitin family member 1 1.41699
CSK c-src tyrosine kinase 1.40298
GRB2 growth factor receptor-bound protein 2 1.38516
ITGB6 integrin, beta 6 1.37078
MMP2 matrix metallopeptidase 2 1.36417
ITGB7 integrin, beta 7 1.33087
FYN FYN proto-oncogene, Src family tyrosine kinase 1.32925
ITGB8 integrin, beta 8 1.32925
TLN1 talin 1 1.32113
FERMT2 fermitin family member 2 1.32005
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.30497
ITGB4 integrin, beta 4 1.29264
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.28623
GRB7 growth factor receptor-bound protein 7 1.26392
MMP9 matrix metallopeptidase 9 1.25653
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.24288
PARVA parvin, alpha 1.22932
DLC1 DLC1 Rho GTPase activating protein 1.22724
PTPRD protein tyrosine phosphatase, receptor type, D 1.22724
CTTN cortactin 1.22464
EGFR epidermal growth factor receptor 1.19931
ARHGAP35 Rho GTPase activating protein 35 1.19571
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.19314
PTEN phosphatase and tensin homolog 1.19057
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.18286
DNM2 dynamin 2 1.17414
TRIP6 thyroid hormone receptor interactor 6 1.12858
JUN jun proto-oncogene 1.12501
TNS2 tensin 2 1.10103
GRP gastrin-releasing peptide 1.08679
TNC tenascin C 1.07613
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.07207
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.07157
TNS4 tensin 4 1.07055
PARVB parvin, beta 1.06954
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.06296
BCAR3 breast cancer anti-estrogen resistance 3 1.05791
MAPK3 mitogen-activated protein kinase 3 1.05236
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.04934
MSN moesin 1.04331
PLAU plasminogen activator, urokinase 1.03779
RB1CC1 RB1-inducible coiled-coil 1 1.03029
EZR ezrin 1.01288
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.01189
LPP LIM domain containing preferred translocation partner in lipoma 1.00547
CD44 CD44 molecule (Indian blood group) 1.003
ITGAV integrin, alpha V 0.996123
SPP1 secreted phosphoprotein 1 0.995632
LHX3 LIM homeobox 3 0.995142
THBS1 thrombospondin 1 0.990247
DOCK1 dedicator of cytokinesis 1 0.980016
TGFB1 transforming growth factor, beta 1 0.97953
CAV1 caveolin 1, caveolae protein, 22kDa 0.972747
PKN1 protein kinase N1 0.972747
RDX radixin 0.96503
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.944007
EPHA2 EPH receptor A2 0.939742
MET MET proto-oncogene, receptor tyrosine kinase 0.935016
LPXN leupaxin 0.914376
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.90321
LASP1 LIM and SH3 protein 1 0.902281
VEGFA vascular endothelial growth factor A 0.894868
KDR kinase insert domain receptor 0.890707
ARHGAP1 Rho GTPase activating protein 1 0.890245
MYLK myosin light chain kinase 0.885628
STARD13 StAR-related lipid transfer (START) domain containing 13 0.873186
CCND1 cyclin D1 0.863068
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.858014
SAR1A secretion associated, Ras related GTPase 1A 0.857555
FERMT3 fermitin family member 3 0.856176
IGF1 insulin-like growth factor 1 (somatomedin C) 0.855717
ZHX2 zinc fingers and homeoboxes 2 0.85388
LIMS2 LIM and senescent cell antigen-like domains 2 0.852042
LIMS3 LIM and senescent cell antigen-like domains 3 0.841941
RHOB ras homolog family member B 0.830007
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.828171
RAP2B RAP2B, member of RAS oncogene family 0.824959
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.820829
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.817158
ARF3 ADP-ribosylation factor 3 0.81624
ARHGAP18 Rho GTPase activating protein 18 0.815781
CIB1 calcium and integrin binding 1 (calmyrin) 0.813028
RAB1B RAB1B, member RAS oncogene family 0.813028
LYN LYN proto-oncogene, Src family tyrosine kinase 0.8089
FGF2 fibroblast growth factor 2 (basic) 0.80523
ERBB2 erb-b2 receptor tyrosine kinase 2 0.804772
CXCL12 chemokine (C-X-C motif) ligand 12 0.798811
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.797895
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.797895
PALLD palladin, cytoskeletal associated protein 0.79652
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.783241
DMD dystrophin 0.781412
MAPK8 mitogen-activated protein kinase 8 0.775928
LAMB2 laminin, beta 2 (laminin S) 0.774558
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.766804
TP53 tumor protein p53 0.764072
IGF1R insulin-like growth factor 1 receptor 0.760433
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.75181
CDH5 cadherin 5, type 2 (vascular endothelium) 0.748641
FLNA filamin A, alpha 0.745929
ZFYVE21 zinc finger, FYVE domain containing 21 0.737813
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.736913
ACTN4 actinin, alpha 4 0.719906
MAPK14 mitogen-activated protein kinase 14 0.712351
NCK2 NCK adaptor protein 2 0.707039
GRPR gastrin-releasing peptide receptor 0.702185
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.699103
MAPK1 mitogen-activated protein kinase 1 0.695148
PFN1 profilin 1 0.69427
EFNA1 ephrin-A1 0.690764
TNS3 tensin 3 0.690326
PARVG parvin, gamma 0.690326
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.689451
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.682027
MAPK11 mitogen-activated protein kinase 11 0.679849
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.678108
SYK spleen tyrosine kinase 0.676368
FLT4 fms-related tyrosine kinase 4 0.675499
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.673328
PTS 6-pyruvoyltetrahydropterin synthase 0.665962
PLEK pleckstrin 0.662503
SORBS1 sorbin and SH3 domain containing 1 0.661208
JAK2 Janus kinase 2 0.658619
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.656464
ITGA6 integrin, alpha 6 0.646574
VCAM1 vascular cell adhesion molecule 1 0.646574
ITGA7 integrin, alpha 7 0.645287
IRS1 insulin receptor substrate 1 0.644858
ICAM1 intercellular adhesion molecule 1 0.643572
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.643572
IBSP integrin-binding sialoprotein 0.642286
CDKN2A cyclin-dependent kinase inhibitor 2A 0.636295
KLF8 Kruppel-like factor 8 0.635868
HRAS Harvey rat sarcoma viral oncogene homolog 0.631598
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.630318
TGM2 transglutaminase 2 0.629465
ZNF384 zinc finger protein 384 0.623079
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.623079
PFN2 profilin 2 0.621804
TLN2 talin 2 0.609932
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.609509
VAV2 vav 2 guanine nucleotide exchange factor 0.606128
FOS FBJ murine osteosarcoma viral oncogene homolog 0.602752
CTGF connective tissue growth factor 0.600644
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.598538
PFN4 profilin family, member 4 0.594753
FLT1 fms-related tyrosine kinase 1 0.592652
ITGB1BP1 integrin beta 1 binding protein 1 0.591392
SDC1 syndecan 1 0.590133
GSN gelsolin 0.588456
LIMS1 LIM and senescent cell antigen-like domains 1 0.584686
PLG plasminogen 0.583012
CD151 CD151 molecule (Raph blood group) 0.582176
RSU1 Ras suppressor protein 1 0.580504
INPPL1 inositol polyphosphate phosphatase-like 1 0.578416
BGLAP bone gamma-carboxyglutamate (gla) protein 0.577999
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.574662
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.574662
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.569248
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.567169
TNF tumor necrosis factor 0.563017
TM4SF5 transmembrane 4 L six family member 5 0.563017
GRB14 growth factor receptor-bound protein 14 0.562602
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.561358
CALR calreticulin 0.5597
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.555559
SMAD2 SMAD family member 2 0.554318
FLNC filamin C, gamma 0.544411
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.543176
EDN1 endothelin 1 0.53906
INS insulin 0.535772
UTRN utrophin 0.535361
SORBS2 sorbin and SH3 domain containing 2 0.534951
CD9 CD9 molecule 0.53454
CDK20 cyclin-dependent kinase 20 0.533719
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.527569
NPHP1 nephronophthisis 1 (juvenile) 0.524704
CAST calpastatin 0.524294
EFS embryonal Fyn-associated substrate 0.523885
FSCN1 fascin actin-bundling protein 1 0.518981
TPM1 tropomyosin 1 (alpha) 0.516532
SHB Src homology 2 domain containing adaptor protein B 0.515308
CALD1 caldesmon 1 0.513677
ESR1 estrogen receptor 1 0.510826
CTNND1 catenin (cadherin-associated protein), delta 1 0.508383
NEBL nebulette 0.507977
TYRO3 TYRO3 protein tyrosine kinase 0.50757
NRP1 neuropilin 1 0.50635
WASL Wiskott-Aldrich syndrome-like 0.503506
LIMK1 LIM domain kinase 1 0.497015
TJP1 tight junction protein 1 0.496205
VAV1 vav 1 guanine nucleotide exchange factor 0.4958
ARHGAP31 Rho GTPase activating protein 31 0.493775
SDC2 syndecan 2 0.493371
GSTA1 glutathione S-transferase alpha 1 0.492966
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.492966
PGM5 phosphoglucomutase 5 0.490539
F2R coagulation factor II (thrombin) receptor 0.490135
TES testin LIM domain protein 0.488519
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.484483
CYR61 cysteine-rich, angiogenic inducer, 61 0.484483
RUNX2 runt-related transcription factor 2 0.484079
ALPPL2 alkaline phosphatase, placental-like 2 0.484079
ALPL alkaline phosphatase, liver/bone/kidney 0.483676
GSTA3 glutathione S-transferase alpha 3 0.483273
ALPP alkaline phosphatase, placental 0.483273
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.48287
GSTA2 glutathione S-transferase alpha 2 0.481661
GSTA4 glutathione S-transferase alpha 4 0.481661
FOCAD focadhesin 0.48005
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.479647
KNG1 kininogen 1 0.478038
PLCG1 phospholipase C, gamma 1 0.475223
FHL2 four and a half LIM domains 2 0.4672
INSR insulin receptor 0.466799
EPHB4 EPH receptor B4 0.465598
RHOJ ras homolog family member J 0.462798
ALB albumin 0.462798
MMP13 matrix metallopeptidase 13 0.461599
TIMP2 TIMP metallopeptidase inhibitor 2 0.459203
SYNM synemin, intermediate filament protein 0.458006
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.456809
MARCKS myristoylated alanine-rich protein kinase C substrate 0.454418
FGF1 fibroblast growth factor 1 (acidic) 0.453621
EGFL6 EGF-like-domain, multiple 6 0.453223
LIM2 lens intrinsic membrane protein 2, 19kDa 0.452029
COL22A1 collagen, type XXII, alpha 1 0.451233
CAPN2 calpain 2, (m/II) large subunit 0.449643
MMP1 matrix metallopeptidase 1 0.446069
LCK LCK proto-oncogene, Src family tyrosine kinase 0.446069
RRAS related RAS viral (r-ras) oncogene homolog 0.441708
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 0.441312
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.441312
MARK2 MAP/microtubule affinity-regulating kinase 2 0.438542
AJUBA ajuba LIM protein 0.43696
ZER1 zyg-11 related, cell cycle regulator 0.435775
BMX BMX non-receptor tyrosine kinase 0.434985
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 0.433407
SMAD3 SMAD family member 3 0.432224
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.431829
ERBB3 erb-b2 receptor tyrosine kinase 3 0.427497
XIRP2 xin actin binding repeat containing 2 0.426711
GRB10 growth factor receptor-bound protein 10 0.425138
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.424745
EPHB2 EPH receptor B2 0.424353
EPHA1 EPH receptor A1 0.423567
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.423174
MMP7 matrix metallopeptidase 7 0.41612
PI3 peptidase inhibitor 3, skin-derived 0.41612
ACTA1 actin, alpha 1, skeletal muscle 0.414946
NET1 neuroepithelial cell transforming 1 0.414555
CXCR4 chemokine (C-X-C motif) receptor 4 0.412601
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.41182
PTPRH protein tyrosine phosphatase, receptor type, H 0.411039
ACTB actin, beta 0.410259
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.408699
SDCBP syndecan binding protein (syntenin) 0.405971
EPB41 erythrocyte membrane protein band 4.1 0.405582
RND3 Rho family GTPase 3 0.405582
CCKBR cholecystokinin B receptor 0.405193
FHL1 four and a half LIM domains 1 0.399751
GP6 glycoprotein VI (platelet) 0.398975
ITGB5 integrin, beta 5 0.396648
MYLK3 myosin light chain kinase 3 0.39471
TTC9 tetratricopeptide repeat domain 9 0.393162
PARP1 poly (ADP-ribose) polymerase 1 0.393162
NEB nebulin 0.392775
NTN1 netrin 1 0.392388
CFL1 cofilin 1 (non-muscle) 0.391615
NPS neuropeptide S 0.388909
TIMP1 TIMP metallopeptidase inhibitor 1 0.388137
MIR197 microRNA 197 0.387365
COL18A1 collagen, type XVIII, alpha 1 0.387365
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.386208
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.385051
PRKD3 protein kinase D3 0.381969
ACTN1 actinin, alpha 1 0.378891
NOV nephroblastoma overexpressed 0.378507
RET ret proto-oncogene 0.375818
ANKRD28 ankyrin repeat domain 28 0.375434
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.37505
GSK3B glycogen synthase kinase 3 beta 0.373132
DIXDC1 DIX domain containing 1 0.369301
LOX lysyl oxidase 0.368153
MMP3 matrix metallopeptidase 3 0.368153
EGFL7 EGF-like-domain, multiple 7 0.367771
STK4 serine/threonine kinase 4 0.364713
LIMD1 LIM domains containing 1 0.364331
NEO1 neogenin 1 0.364331
ACTG1 actin gamma 1 0.363949
PRPF4B pre-mRNA processing factor 4B 0.362804
MYOCD myocardin 0.35899
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.358228
CD82 CD82 molecule 0.358228
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.358228
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.355944
TMSB4X thymosin beta 4, X-linked 0.355944
SIRPA signal-regulatory protein alpha 0.355183
TLK1 tousled-like kinase 1 0.354422
GAST gastrin 0.354422
CCR1 chemokine (C-C motif) receptor 1 0.354422
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.354042
S100A4 S100 calcium binding protein A4 0.351762
ATG13 autophagy related 13 0.351002
FBN1 fibrillin 1 0.351002
ITGA1 integrin, alpha 1 0.348346
ITGA8 integrin, alpha 8 0.347967
ESAM endothelial cell adhesion molecule 0.347208
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.346829
NOS3 nitric oxide synthase 3 (endothelial cell) 0.344556
WNT5A wingless-type MMTV integration site family, member 5A 0.344178
RAP1A RAP1A, member of RAS oncogene family 0.343421
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.343042
ISL1 ISL LIM homeobox 1 0.341907
TESK1 testis-specific kinase 1 0.340773
PDCD10 programmed cell death 10 0.340395
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.339261
NF2 neurofibromin 2 (merlin) 0.339261
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.339261
EVL Enah/Vasp-like 0.338884
XIRP1 xin actin binding repeat containing 1 0.335864
PHACTR4 phosphatase and actin regulator 4 0.335487
LAMA5 laminin, alpha 5 0.33511
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.33511
RABL3 RAB, member of RAS oncogene family-like 3 0.331342
FGR FGR proto-oncogene, Src family tyrosine kinase 0.328708
NELL1 NEL-like 1 (chicken) 0.328332
RTKN rhotekin 0.327581
BMP2 bone morphogenetic protein 2 0.326078
RAVER1 ribonucleoprotein, PTB-binding 1 0.325702
PEPD peptidase D 0.323825
STK25 serine/threonine kinase 25 0.323075
DAP death-associated protein 0.320451
RHOA ras homolog family member A 0.320451
EPS8 epidermal growth factor receptor pathway substrate 8 0.320077
ULK1 unc-51 like autophagy activating kinase 1 0.319702
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.319328
PDGFB platelet-derived growth factor beta polypeptide 0.318953
COL1A1 collagen, type I, alpha 1 0.318579
MACF1 microtubule-actin crosslinking factor 1 0.317456
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.315212
MAPK7 mitogen-activated protein kinase 7 0.314091
THY1 Thy-1 cell surface antigen 0.313718
MAP2K1 mitogen-activated protein kinase kinase 1 0.312224
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.311105
HCK HCK proto-oncogene, Src family tyrosine kinase 0.311105
ANK1 ankyrin 1, erythrocytic 0.308122
FMN1 formin 1 0.306632
SRCIN1 SRC kinase signaling inhibitor 1 0.30626
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.305515
ANGPT2 angiopoietin 2 0.304027
ANXA5 annexin A5 0.303283
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.301425
RHOBTB2 Rho-related BTB domain containing 2 0.300682
DDR1 discoidin domain receptor tyrosine kinase 1 0.300311
NRP2 neuropilin 2 0.29994
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.299569
COL13A1 collagen, type XIII, alpha 1 0.299197
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.299197
CD47 CD47 molecule 0.298826
LGI3 leucine-rich repeat LGI family, member 3 0.297713
ADAM12 ADAM metallopeptidase domain 12 0.297342
MIR95 microRNA 95 0.29623
KRAS Kirsten rat sarcoma viral oncogene homolog 0.29586
ARF6 ADP-ribosylation factor 6 0.293267
NOX1 NADPH oxidase 1 0.292527
FLNB filamin B, beta 0.291787
GJA1 gap junction protein, alpha 1, 43kDa 0.291047
TYK2 tyrosine kinase 2 0.288091
WAS Wiskott-Aldrich syndrome 0.285876
SCARA5 scavenger receptor class A, member 5 0.285876
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.283663
ARHGAP10 Rho GTPase activating protein 10 0.282926
TNK2 tyrosine kinase, non-receptor, 2 0.282926
NGF nerve growth factor (beta polypeptide) 0.280716
IL1B interleukin 1, beta 0.27998
AXL AXL receptor tyrosine kinase 0.27998
SOS1 son of sevenless homolog 1 (Drosophila) 0.279612
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.278877
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.277038
MCF2 MCF.2 cell line derived transforming sequence 0.277038
TIAM1 T-cell lymphoma invasion and metastasis 1 0.275936
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.274468
CDK2 cyclin-dependent kinase 2 0.2708
LAMA2 laminin, alpha 2 0.269701
FGFR2 fibroblast growth factor receptor 2 0.269701
BSG basigin (Ok blood group) 0.268603
DCN decorin 0.267139
MERTK MER proto-oncogene, tyrosine kinase 0.267139
OCLN occludin 0.267139
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.266408
PODXL podocalyxin-like 0.266042
BST1 bone marrow stromal cell antigen 1 0.266042
LGALS3 lectin, galactoside-binding, soluble, 3 0.266042
IL32 interleukin 32 0.26385
LOXL2 lysyl oxidase-like 2 0.26166
CSPG4 chondroitin sulfate proteoglycan 4 0.260931
CXCL8 chemokine (C-X-C motif) ligand 8 0.256197
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.256197
AR androgen receptor 0.25547
CDCP1 CUB domain containing protein 1 0.255107
LMO7 LIM domain 7 0.253291
EPHA3 EPH receptor A3 0.252927
MYOM1 myomesin 1 0.252564
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.252202
MAPK9 mitogen-activated protein kinase 9 0.250751
IQGAP1 IQ motif containing GTPase activating protein 1 0.24894
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.248216
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.247492
MARK3 MAP/microtubule affinity-regulating kinase 3 0.245323
EFNB2 ephrin-B2 0.245323
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.243519
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.243158
LPAR2 lysophosphatidic acid receptor 2 0.243158
IRS2 insulin receptor substrate 2 0.242797
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.240996
STARD8 StAR-related lipid transfer (START) domain containing 8 0.240636
MIR15B microRNA 15b 0.239916
RPSA ribosomal protein SA 0.238837
FBLIM1 filamin binding LIM protein 1 0.237042
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.237042
PGR progesterone receptor 0.235607
LAMA3 laminin, alpha 3 0.235607
TMIGD2 transmembrane and immunoglobulin domain containing 2 0.235607
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.235249
CPNE3 copine III 0.234891
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.234533
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.234174
ANKRD13A ankyrin repeat domain 13A 0.232744
RHOU ras homolog family member U 0.231315
CDK5 cyclin-dependent kinase 5 0.230958
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.228464
HRG histidine-rich glycoprotein 0.228108
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.227041
ARHGAP30 Rho GTPase activating protein 30 0.227041
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.225622
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.225622
CDK4 cyclin-dependent kinase 4 0.225622
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.225267
TENM4 teneurin transmembrane protein 4 0.224913
SLK STE20-like kinase 0.223143
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.222083
EPHA5 EPH receptor A5 0.221025
GRAP2 GRB2-related adaptor protein 2 0.220321
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.219617
PF4 platelet factor 4 0.219265
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.218914
PDLIM2 PDZ and LIM domain 2 (mystique) 0.218212
BAX BCL2-associated X protein 0.217861
EDNRB endothelin receptor type B 0.217511
EPHA4 EPH receptor A4 0.217511
COL6A3 collagen, type VI, alpha 3 0.21681
VWF von Willebrand factor 0.216111
KLHL11 kelch-like family member 11 0.215412
CRIP2 cysteine-rich protein 2 0.215412
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.214366
RHOD ras homolog family member D 0.214017
MAP2K7 mitogen-activated protein kinase kinase 7 0.21228
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.21124
CCNB1 cyclin B1 0.21124
LAYN layilin 0.210894
SFTPA2 surfactant protein A2 0.210203
GPR52 G protein-coupled receptor 52 0.209858
AMER2 APC membrane recruitment protein 2 0.209858
FSCN3 fascin actin-bundling protein 3, testicular 0.209169
BCL2L1 BCL2-like 1 0.208137
HBEGF heparin-binding EGF-like growth factor 0.207794
CTHRC1 collagen triple helix repeat containing 1 0.207451
BHLHE22 basic helix-loop-helix family, member e22 0.207451
TNXA tenascin XA (pseudogene) 0.207108
TNXB tenascin XB 0.206766
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.20574
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.20574
MIR223 microRNA 223 0.204378
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.204378
PLK4 polo-like kinase 4 0.203699
COL3A1 collagen, type III, alpha 1 0.203361
EFNB3 ephrin-B3 0.203022
ARF5 ADP-ribosylation factor 5 0.202346
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.200663
BIRC5 baculoviral IAP repeat containing 5 0.199659
POSTN periostin, osteoblast specific factor 0.199325
ARHGAP11A Rho GTPase activating protein 11A 0.198325
PPP6C protein phosphatase 6, catalytic subunit 0.197993
NCKIPSD NCK interacting protein with SH3 domain 0.197993
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.19733
FSCN2 fascin actin-bundling protein 2, retinal 0.196999
NOX4 NADPH oxidase 4 0.196669
JUP junction plakoglobin 0.19601
PPP5C protein phosphatase 5, catalytic subunit 0.19307
NHSL1 NHS-like 1 0.192746
NHSL2 NHS-like 2 0.192746
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 0.192746
DCC DCC netrin 1 receptor 0.192423
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.1921
EPHA7 EPH receptor A7 0.191777
CD34 CD34 molecule 0.191456
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.189857
PLAT plasminogen activator, tissue 0.189539
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.188905
VCAN versican 0.18796
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.187646
PLXNC1 plexin C1 0.186397
TIAM2 T-cell lymphoma invasion and metastasis 2 0.186397
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.186397
EIF4E eukaryotic translation initiation factor 4E 0.18516
SELE selectin E 0.183935
TESK2 testis-specific kinase 2 0.183328
ETV4 ets variant 4 0.182723
ANXA2 annexin A2 0.182723
THSD7A thrombospondin, type I, domain containing 7A 0.182422
DMTF1 cyclin D binding myb-like transcription factor 1 0.181524
TTN titin 0.181227
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.181227
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.180634
FBLN2 fibulin 2 0.180634
DUX4L4 double homeobox 4 like 4 0.180339
DUX4L9 double homeobox 4 like 9 0.180339
FBLN7 fibulin 7 0.178588
WISP1 WNT1 inducible signaling pathway protein 1 0.178011
SLC16A11 solute carrier family 16, member 11 0.177724
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.177724
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.17687
CAPNS1 calpain, small subunit 1 0.17687
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.176305
ASB2 ankyrin repeat and SOCS box containing 2 0.175745
PNMA6A paraneoplastic Ma antigen family member 6A 0.175188
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.174635
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.174361
HAS2 hyaluronan synthase 2 0.174361
TRIM15 tripartite motif containing 15 0.173814
FGFR3 fibroblast growth factor receptor 3 0.173814
DSP desmoplakin 0.173814
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.171937
ZDHHC1 zinc finger, DHHC-type containing 1 0.171937
CCL4 chemokine (C-C motif) ligand 4 0.17141
EPHB1 EPH receptor B1 0.171149
AMER3 APC membrane recruitment protein 3 0.170888
ATG101 autophagy related 101 0.170629
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.169604
RB1 retinoblastoma 1 0.169099
CSRP2 cysteine and glycine-rich protein 2 0.168847
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.168598
ARF1 ADP-ribosylation factor 1 0.168349
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.168101
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.168101
RAP1B RAP1B, member of RAS oncogene family 0.168101
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.167856
IL6 interleukin 6 0.167611
SVIL supervillin 0.166643
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 0.165932
LDB2 LIM domain binding 2 0.165231
PNPLA5 patatin-like phospholipase domain containing 5 0.165231
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.16477
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.164542
F11R F11 receptor 0.164542
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.164315
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.164089
PVR poliovirus receptor 0.164089
SPDEF SAM pointed domain containing ETS transcription factor 0.163641
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.16233
CAV2 caveolin 2 0.162117
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.162117
FRK fyn-related Src family tyrosine kinase 0.161905
SFRP4 secreted frizzled-related protein 4 0.160863
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.160863
GFAP glial fibrillary acidic protein 0.160456
MYOD1 myogenic differentiation 1 0.159856
FGF7 fibroblast growth factor 7 0.159658
ERBB4 erb-b2 receptor tyrosine kinase 4 0.158882
JAK1 Janus kinase 1 0.158692
COL5A2 collagen, type V, alpha 2 0.158692
SH2D3C SH2 domain containing 3C 0.158502
PNCK pregnancy up-regulated nonubiquitous CaM kinase 0.157397
TSC2 tuberous sclerosis 2 0.156688
ADAM15 ADAM metallopeptidase domain 15 0.156688
PLXND1 plexin D1 0.156688
CXCR1 chemokine (C-X-C motif) receptor 1 0.156688
LPAR6 lysophosphatidic acid receptor 6 0.156688
MKX mohawk homeobox 0.148652
ACHE acetylcholinesterase (Yt blood group) 0.146865
CIB2 calcium and integrin binding family member 2 0.142592
GAS2 growth arrest-specific 2 0.142437
VAMP5 vesicle-associated membrane protein 5 0.141528
LDB3 LIM domain binding 3 0.141141
DMPK dystrophia myotonica-protein kinase 0.140922
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 0.140889
LAX1 lymphocyte transmembrane adaptor 1 0.140785
MYOT myotilin 0.139667
NES nestin 0.139586
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.139251
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.138745
MYOZ1 myozenin 1 0.138699
DUX4L8 double homeobox 4 like 8 0.138699
AKR1C4 aldo-keto reductase family 1, member C4 0.138315
SNX5 sorting nexin 5 0.138307
TNMD tenomodulin 0.136907
COL6A2 collagen, type VI, alpha 2 0.136897
SNTA1 syntrophin, alpha 1 0.136877
COMP cartilage oligomeric matrix protein 0.13678
COL14A1 collagen, type XIV, alpha 1 0.13677
GJB6 gap junction protein, beta 6, 30kDa 0.136338
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.136327
PRG4 proteoglycan 4 0.136171
DES desmin 0.135927
THBS4 thrombospondin 4 0.135776
MATN3 matrilin 3 0.134718
SCX scleraxis basic helix-loop-helix transcription factor 0.134571
SSPN sarcospan 0.13451
SV2B synaptic vesicle glycoprotein 2B 0.134435
WNT2 wingless-type MMTV integration site family member 2 0.134385
LHB luteinizing hormone beta polypeptide 0.134054
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.133832
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.133233
CLTC clathrin, heavy chain (Hc) 0.133191
IPO7 importin 7 0.133092
TGFBI transforming growth factor, beta-induced, 68kDa 0.132949
CAV3 caveolin 3 0.132745
COL6A1 collagen, type VI, alpha 1 0.131419
DST dystonin 0.131082
FGF8 fibroblast growth factor 8 (androgen-induced) 0.130857
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.130857
CHAT choline O-acetyltransferase 0.130592
PGM1 phosphoglucomutase 1 0.129852
SURF1 surfeit 1 0.129737
BCHE butyrylcholinesterase 0.129305
ADRA1D adrenoceptor alpha 1D 0.129184
MYOM2 myomesin 2 0.128624
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.128168
PTPRU protein tyrosine phosphatase, receptor type, U 0.128168
PABPN1 poly(A) binding protein, nuclear 1 0.128102