cell-substrate adherens junction Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An adherens junction which connects a cell to the extracellular matrix. (Gene Ontology, GO_0005924)
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Genes

361 proteins localized to the cell-substrate adherens junction cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.663342
RPLP2 ribosomal protein, large, P2 0.663342
RPLP1 ribosomal protein, large, P1 0.663342
RPLP0 ribosomal protein, large, P0 0.663342
DDR2 discoidin domain receptor tyrosine kinase 2 0.663342
TES testin LIM domain protein 0.663342
LMO7 LIM domain 7 0.663342
AFAP1 actin filament associated protein 1 0.663342
LASP1 LIM and SH3 protein 1 0.663342
CDC42 cell division cycle 42 0.663342
MSN moesin 0.663342
SNAP23 synaptosomal-associated protein, 23kDa 0.663342
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.663342
HMGA1 high mobility group AT-hook 1 0.663342
CNN1 calponin 1, basic, smooth muscle 0.663342
CNN3 calponin 3, acidic 0.663342
CNN2 calponin 2 0.663342
RPL13A ribosomal protein L13a 0.663342
TNC tenascin C 0.663342
SCARB2 scavenger receptor class B, member 2 0.663342
RRAS related RAS viral (r-ras) oncogene homolog 0.663342
SPRY4 sprouty homolog 4 (Drosophila) 0.663342
AKAP12 A kinase (PRKA) anchor protein 12 0.663342
EGFR epidermal growth factor receptor 0.663342
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.663342
NEXN nexilin (F actin binding protein) 0.663342
ENAH enabled homolog (Drosophila) 0.663342
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.663342
PLEC plectin 0.663342
CSRP1 cysteine and glycine-rich protein 1 0.663342
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.663342
ADGRE5 adhesion G protein-coupled receptor E5 0.663342
LIMA1 LIM domain and actin binding 1 0.663342
PDLIM1 PDZ and LIM domain 1 0.663342
RAB10 RAB10, member RAS oncogene family 0.663342
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.663342
EHD3 EH-domain containing 3 0.663342
PDIA3 protein disulfide isomerase family A, member 3 0.663342
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 0.663342
DIXDC1 DIX domain containing 1 0.663342
CSRP2 cysteine and glycine-rich protein 2 0.663342
CORO1C coronin, actin binding protein, 1C 0.663342
RPL31 ribosomal protein L31 0.663342
VCL vinculin 0.663342
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.663342
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.663342
LIMD1 LIM domains containing 1 0.663342
PTK2 protein tyrosine kinase 2 0.663342
PTK7 protein tyrosine kinase 7 (inactive) 0.663342
FBLIM1 filamin binding LIM protein 1 0.663342
MISP mitotic spindle positioning 0.663342
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.663342
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.663342
FOCAD focadhesin 0.663342
FLOT1 flotillin 1 0.663342
FLOT2 flotillin 2 0.663342
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.663342
P4HB prolyl 4-hydroxylase, beta polypeptide 0.663342
EFNB2 ephrin-B2 0.663342
MAP2K2 mitogen-activated protein kinase kinase 2 0.663342
MAP2K1 mitogen-activated protein kinase kinase 1 0.663342
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.663342
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.663342
S100A7 S100 calcium binding protein A7 0.663342
RPL38 ribosomal protein L38 0.663342
RPL30 ribosomal protein L30 0.663342
BSG basigin (Ok blood group) 0.663342
SDCBP syndecan binding protein (syntenin) 0.663342
CAT catalase 0.663342
FBLN7 fibulin 7 0.663342
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.663342
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.663342
CD151 CD151 molecule (Raph blood group) 0.663342
TPM4 tropomyosin 4 0.663342
RPS3A ribosomal protein S3A 0.663342
KIF23 kinesin family member 23 0.663342
FERMT1 fermitin family member 1 0.663342
RAB21 RAB21, member RAS oncogene family 0.663342
TNS3 tensin 3 0.663342
TNS1 tensin 1 0.663342
TNS4 tensin 4 0.663342
ALCAM activated leukocyte cell adhesion molecule 0.663342
CORO1B coronin, actin binding protein, 1B 0.663342
CD99 CD99 molecule 0.663342
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.663342
TSPAN4 tetraspanin 4 0.663342
TSPAN9 tetraspanin 9 0.663342
PDCD6IP programmed cell death 6 interacting protein 0.663342
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.663342
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.663342
HSPA8 heat shock 70kDa protein 8 0.663342
RPS4X ribosomal protein S4, X-linked 0.663342
VASP vasodilator-stimulated phosphoprotein 0.663342
TRIOBP TRIO and F-actin binding protein 0.663342
MRC2 mannose receptor, C type 2 0.663342
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.663342
LAP3 leucine aminopeptidase 3 0.663342
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.663342
PALLD palladin, cytoskeletal associated protein 0.663342
PDPK1 3-phosphoinositide dependent protein kinase 1 0.663342
PTK2B protein tyrosine kinase 2 beta 0.663342
IQGAP1 IQ motif containing GTPase activating protein 1 0.663342
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.663342
RPS7 ribosomal protein S7 0.663342
RPS5 ribosomal protein S5 0.663342
RPS3 ribosomal protein S3 0.663342
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.663342
CAPN5 calpain 5 0.663342
CAPN2 calpain 2, (m/II) large subunit 0.663342
CAPN1 calpain 1, (mu/I) large subunit 0.663342
NFASC neurofascin 0.663342
PARVB parvin, beta 0.663342
PARVA parvin, alpha 0.663342
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.663342
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
RPS2 ribosomal protein S2 0.663342
RPS9 ribosomal protein S9 0.663342
RPS8 ribosomal protein S8 0.663342
RPL27 ribosomal protein L27 0.663342
RPL23 ribosomal protein L23 0.663342
RPL22 ribosomal protein L22 0.663342
ADD1 adducin 1 (alpha) 0.663342
STX16 syntaxin 16 0.663342
RPL10A ribosomal protein L10a 0.663342
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.663342
CD9 CD9 molecule 0.663342
RPS10 ribosomal protein S10 0.663342
RPS17 ribosomal protein S17 0.663342
RPS16 ribosomal protein S16 0.663342
RPS15 ribosomal protein S15 0.663342
RPS14 ribosomal protein S14 0.663342
RPS19 ribosomal protein S19 0.663342
RPS18 ribosomal protein S18 0.663342
RDX radixin 0.663342
RPS11 ribosomal protein S11 0.663342
RPS13 ribosomal protein S13 0.663342
DNM2 dynamin 2 0.663342
CFL1 cofilin 1 (non-muscle) 0.663342
GJA1 gap junction protein, alpha 1, 43kDa 0.663342
PLAUR plasminogen activator, urokinase receptor 0.663342
NCSTN nicastrin 0.663342
AHNAK AHNAK nucleoprotein 0.663342
CLTC clathrin, heavy chain (Hc) 0.663342
MPRIP myosin phosphatase Rho interacting protein 0.663342
VIM vimentin 0.663342
ARF1 ADP-ribosylation factor 1 0.663342
ARF6 ADP-ribosylation factor 6 0.663342
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.663342
FAP fibroblast activation protein, alpha 0.663342
PCBP2 poly(rC) binding protein 2 0.663342
GSN gelsolin 0.663342
PABPC1 poly(A) binding protein, cytoplasmic 1 0.663342
DLC1 DLC1 Rho GTPase activating protein 0.663342
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.663342
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.663342
L1CAM L1 cell adhesion molecule 0.663342
ILK integrin-linked kinase 0.663342
CD44 CD44 molecule (Indian blood group) 0.663342
CD46 CD46 molecule, complement regulatory protein 0.663342
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.663342
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.663342
GRB7 growth factor receptor-bound protein 7 0.663342
TEK TEK tyrosine kinase, endothelial 0.663342
RPL18 ribosomal protein L18 0.663342
RPL19 ribosomal protein L19 0.663342
ZYX zyxin 0.663342
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.663342
CDH13 cadherin 13 0.663342
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.663342
CD59 CD59 molecule, complement regulatory protein 0.663342
CD99L2 CD99 molecule-like 2 0.663342
HSPG2 heparan sulfate proteoglycan 2 0.663342
KRAS Kirsten rat sarcoma viral oncogene homolog 0.663342
ADAM9 ADAM metallopeptidase domain 9 0.663342
RPL8 ribosomal protein L8 0.663342
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.663342
PROCR protein C receptor, endothelial 0.663342
RPS29 ribosomal protein S29 0.663342
DST dystonin 0.663342
SCARF2 scavenger receptor class F, member 2 0.663342
RPL37A ribosomal protein L37a 0.663342
PVR poliovirus receptor 0.663342
MAPK3 mitogen-activated protein kinase 3 0.663342
MAPK1 mitogen-activated protein kinase 1 0.663342
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.663342
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.663342
RPL9 ribosomal protein L9 0.663342
RPL6 ribosomal protein L6 0.663342
FHL3 four and a half LIM domains 3 0.663342
FHL1 four and a half LIM domains 1 0.663342
SYNE1 spectrin repeat containing, nuclear envelope 1 0.663342
SYNE2 spectrin repeat containing, nuclear envelope 2 0.663342
FLNA filamin A, alpha 0.663342
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.663342
PLAU plasminogen activator, urokinase 0.663342
B2M beta-2-microglobulin 0.663342
FHL2 four and a half LIM domains 2 0.663342
ACTC1 actin, alpha, cardiac muscle 1 0.663342
LAYN layilin 0.663342
RPL4 ribosomal protein L4 0.663342
RPL5 ribosomal protein L5 0.663342
RPL3 ribosomal protein L3 0.663342
RPL7 ribosomal protein L7 0.663342
JAK1 Janus kinase 1 0.663342
MCAM melanoma cell adhesion molecule 0.663342
HSPA1B heat shock 70kDa protein 1B 0.663342
HSPA1A heat shock 70kDa protein 1A 0.663342
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 0.663342
ITGA11 integrin, alpha 11 0.663342
ITGA8 integrin, alpha 8 0.663342
SORBS3 sorbin and SH3 domain containing 3 0.663342
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.663342
ADAM10 ADAM metallopeptidase domain 10 0.663342
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.663342
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 0.663342
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.663342
ACTN1 actinin, alpha 1 0.663342
ACTN4 actinin, alpha 4 0.663342
RPL12 ribosomal protein L12 0.663342
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.663342
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.663342
ITGA1 integrin, alpha 1 0.663342
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.663342
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.663342
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.663342
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.663342
ITGA6 integrin, alpha 6 0.663342
ITGAV integrin, alpha V 0.663342
IGF2R insulin-like growth factor 2 receptor 0.663342
EZR ezrin 0.663342
GDI2 GDP dissociation inhibitor 2 0.663342
DOCK7 dedicator of cytokinesis 7 0.663342
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.663342
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.663342
EPHA2 EPH receptor A2 0.663342
ZFYVE21 zinc finger, FYVE domain containing 21 0.663342
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.663342
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.663342
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.663342
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.663342
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.663342
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.663342
CALR calreticulin 0.663342
FLRT2 fibronectin leucine rich transmembrane protein 2 0.663342
FAT1 FAT atypical cadherin 1 0.663342
FERMT2 fermitin family member 2 0.663342
RPL7A ribosomal protein L7a 0.663342
NRP1 neuropilin 1 0.663342
SYNPO2 synaptopodin 2 0.663342
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.663342
ITGB5 integrin, beta 5 0.663342
PGM5 phosphoglucomutase 5 0.663342
TGM2 transglutaminase 2 0.663342
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.663342
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.663342
ANXA1 annexin A1 0.663342
ANXA5 annexin A5 0.663342
ANXA6 annexin A6 0.663342
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.663342
PXN paxillin 0.663342
NCKAP1 NCK-associated protein 1 0.663342
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.663342
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.663342
ACTB actin, beta 0.663342
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.663342
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.663342
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.663342
CD81 CD81 molecule 0.663342
FES FES proto-oncogene, tyrosine kinase 0.663342
SVIL supervillin 0.663342
THY1 Thy-1 cell surface antigen 0.663342
TNS2 tensin 2 0.663342
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.663342
RHOB ras homolog family member B 0.663342
RHOA ras homolog family member A 0.663342
RHOG ras homolog family member G 0.663342
CTTN cortactin 0.663342
ENG endoglin 0.663342
FLT1 fms-related tyrosine kinase 1 0.663342
TLN2 talin 2 0.663342
TLN1 talin 1 0.663342
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.663342
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.663342
PFN1 profilin 1 0.663342
HYOU1 hypoxia up-regulated 1 0.663342
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.663342
FLNB filamin B, beta 0.663342
FLNC filamin C, gamma 0.663342
LPP LIM domain containing preferred translocation partner in lipoma 0.663342
ICAM1 intercellular adhesion molecule 1 0.663342
NUMB numb homolog (Drosophila) 0.663342
JUP junction plakoglobin 0.663342
ARHGAP24 Rho GTPase activating protein 24 0.663342
FZD1 frizzled class receptor 1 0.663342
TWF1 twinfilin actin binding protein 1 0.663342
PEAK1 pseudopodium-enriched atypical kinase 1 0.663342
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.663342
PRUNE prune exopolyphosphatase 0.663342
CSPG4 chondroitin sulfate proteoglycan 4 0.663342
MPZL1 myelin protein zero-like 1 0.663342
HSPB1 heat shock 27kDa protein 1 0.663342
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.663342
CAV1 caveolin 1, caveolae protein, 22kDa 0.663342
TRIP6 thyroid hormone receptor interactor 6 0.663342
ARHGAP22 Rho GTPase activating protein 22 0.663342
MARCKS myristoylated alanine-rich protein kinase C substrate 0.663342
RND3 Rho family GTPase 3 0.663342
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.663342
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.663342
FZD2 frizzled class receptor 2 0.663342
MME membrane metallo-endopeptidase 0.663342
RPS18P12 ribosomal protein S18 pseudogene 12 0.663342
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.663342
LIMS1 LIM and senescent cell antigen-like domains 1 0.663342
LIMS2 LIM and senescent cell antigen-like domains 2 0.663342
LPXN leupaxin 0.663342
PDLIM7 PDZ and LIM domain 7 (enigma) 0.237908
SORBS1 sorbin and SH3 domain containing 1 0.237908
PNMA1 paraneoplastic Ma antigen 1 0.237908
BCAR1 breast cancer anti-estrogen resistance 1 0.237908
C2CD4B C2 calcium-dependent domain containing 4B 0.237908
SDC1 syndecan 1 0.237908
PDLIM2 PDZ and LIM domain 2 (mystique) 0.237908
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.237908
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.237908
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.237908
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.237908
HCK HCK proto-oncogene, Src family tyrosine kinase 0.237908
MDC1 mediator of DNA-damage checkpoint 1 0.237908
ACTN2 actinin, alpha 2 0.237908
NUP214 nucleoporin 214kDa 0.237908
ZNF185 zinc finger protein 185 (LIM domain) 0.237908
EVL Enah/Vasp-like 0.237908
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.237908
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 0.237908
KIF22 kinesin family member 22 0.237908
TADA1 transcriptional adaptor 1 0.237908
LIG4 ligase IV, DNA, ATP-dependent 0.237908
AIF1L allograft inflammatory factor 1-like 0.237908
AATF apoptosis antagonizing transcription factor 0.237908
KDM4B lysine (K)-specific demethylase 4B 0.237908
NRAP nebulin-related anchoring protein 0.237908
REXO2 RNA exonuclease 2 0.237908
PTPRC protein tyrosine phosphatase, receptor type, C 0.237908
SENP1 SUMO1/sentrin specific peptidase 1 0.237908
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.237908
EBAG9 estrogen receptor binding site associated, antigen, 9 0.237908
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.098109
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.098109
CIB2 calcium and integrin binding family member 2 0.03318
NOX4 NADPH oxidase 4 0.03318
AJUBA ajuba LIM protein 0.03318
ITGA7 integrin, alpha 7 0.03318
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.03318
SDC4 syndecan 4 0.03318
SMPX small muscle protein, X-linked 0.03318
LIMK1 LIM domain kinase 1 0.03318
EPB41L5 erythrocyte membrane protein band 4.1 like 5 0.03318
ZNF384 zinc finger protein 384 0.03318
NEURL2 neuralized E3 ubiquitin protein ligase 2 0.03318