cell trailing edge Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The area of a motile cell opposite to the direction of movement. (Gene Ontology, GO_0031254)
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Genes

104 proteins co-occuring with the cell trailing edge cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ICAM3 intercellular adhesion molecule 3 1.47796
MSN moesin 1.45307
EZR ezrin 1.36527
RDX radixin 1.31358
SELPLG selectin P ligand 1.30658
ICAM1 intercellular adhesion molecule 1 1.10154
CXCL12 chemokine (C-X-C motif) ligand 12 0.999068
CD44 CD44 molecule (Indian blood group) 0.980016
FLOT1 flotillin 1 0.950665
CTSZ cathepsin Z 0.813487
ZBTB20 zinc finger and BTB domain containing 20 0.807524
FLOT2 flotillin 2 0.783241
SPN sialophorin 0.779583
RHOT2 ras homolog family member T2 0.751357
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.727494
SYTL5 synaptotagmin-like 5 0.648721
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.627335
CDC42 cell division cycle 42 0.624355
LPAR2 lysophosphatidic acid receptor 2 0.587618
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.585942
ORAI1 ORAI calcium release-activated calcium modulator 1 0.546885
SEPT5 septin 5 0.534951
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.527569
LPAR4 lysophosphatidic acid receptor 4 0.512047
VAV1 vav 1 guanine nucleotide exchange factor 0.510418
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.498636
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.497826
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.497015
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.483676
SELL selectin L 0.476429
ICAM2 intercellular adhesion molecule 2 0.450836
IL15 interleukin 15 0.450836
BST1 bone marrow stromal cell antigen 1 0.432224
CCR2 chemokine (C-C motif) receptor 2 0.427891
DPYSL2 dihydropyrimidinase-like 2 0.42082
CCL21 chemokine (C-C motif) ligand 21 0.419252
CCR7 chemokine (C-C motif) receptor 7 0.41886
SHARPIN SHANK-associated RH domain interactor 0.414164
TUBA1B tubulin, alpha 1b 0.409869
KIDINS220 kinase D-interacting substrate, 220kDa 0.406361
VCAM1 vascular cell adhesion molecule 1 0.399363
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.387751
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.363185
SYK spleen tyrosine kinase 0.356705
SHPK sedoheptulokinase 0.352142
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.345692
RHOT1 ras homolog family member T1 0.342664
MYLK myosin light chain kinase 0.341529
CTSK cathepsin K 0.336241
SNX27 sorting nexin family member 27 0.334733
STIM1 stromal interaction molecule 1 0.331342
PLCB2 phospholipase C, beta 2 0.329461
CD4 CD4 molecule 0.327956
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.325327
BICD2 bicaudal D homolog 2 (Drosophila) 0.321201
ISL1 ISL LIM homeobox 1 0.320826
DNM2 dynamin 2 0.314839
SRCIN1 SRC kinase signaling inhibitor 1 0.308494
PLSCR1 phospholipid scramblase 1 0.296972
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.295119
CD34 CD34 molecule 0.293267
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.276304
MCF2 MCF.2 cell line derived transforming sequence 0.260202
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.258745
MYH9 myosin, heavy chain 9, non-muscle 0.258381
C5AR1 complement component 5a receptor 1 0.256561
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.255107
MST1 macrophage stimulating 1 0.248216
PKN1 protein kinase N1 0.244962
FYB FYN binding protein 0.23776
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.23776
PLAUR plasminogen activator, urokinase receptor 0.226686
VCL vinculin 0.224558
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.224204
FN1 fibronectin 1 0.22385
SDC1 syndecan 1 0.220673
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.218212
HAX1 HCLS1 associated protein X-1 0.21646
OSGEP O-sialoglycoprotein endopeptidase 0.213322
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.213322
RAB27A RAB27A, member RAS oncogene family 0.210203
SELE selectin E 0.209513
GYPE glycophorin E (MNS blood group) 0.208137
CNOT1 CCR4-NOT transcription complex, subunit 1 0.198658
GPC1 glypican 1 0.196339
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.196339
MARCKS myristoylated alanine-rich protein kinase C substrate 0.19601
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.195025
WAS Wiskott-Aldrich syndrome 0.194698
SFTPA1 surfactant protein A1 0.191456
CXCR5 chemokine (C-X-C motif) receptor 5 0.190175
MCM6 minichromosome maintenance complex component 6 0.188905
STX8 syntaxin 8 0.188274
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.18702
RAB27B RAB27B, member RAS oncogene family 0.180339
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.179459
PRIMA1 proline rich membrane anchor 1 0.177724
SYT7 synaptotagmin VII 0.173003
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.172201
CXCL8 chemokine (C-X-C motif) ligand 8 0.169604
LEPR leptin receptor 0.168847
CLTC clathrin, heavy chain (Hc) 0.168349
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.166405
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.161068