cell leading edge Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The area of a motile cell closest to the direction of movement. (Gene Ontology, GO_0031252)
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Genes

456 proteins co-occuring with the cell leading edge cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 2.61375
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 2.6076
CDC42 cell division cycle 42 2.23752
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.07651
CTTN cortactin 1.73814
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.54291
PXN paxillin 1.50114
VASP vasodilator-stimulated phosphoprotein 1.44686
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.42092
VCL vinculin 1.39907
FN1 fibronectin 1 1.35868
VAV2 vav 2 guanine nucleotide exchange factor 1.35539
PLEK pleckstrin 1.29639
DOCK1 dedicator of cytokinesis 1 1.27717
WAS Wiskott-Aldrich syndrome 1.25232
PKN1 protein kinase N1 1.23818
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.23713
CNTNAP1 contactin associated protein 1 1.20705
EZR ezrin 1.2055
FSCN1 fascin actin-bundling protein 1 1.20395
MCF2 MCF.2 cell line derived transforming sequence 1.188
BAIAP2 BAI1-associated protein 2 1.1844
TIAM1 T-cell lymphoma invasion and metastasis 1 1.16645
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.07461
ARF6 ADP-ribosylation factor 6 1.07359
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.06397
MSN moesin 1.05085
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.05035
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.02829
FSCN3 fascin actin-bundling protein 3, testicular 1.01883
FSCN2 fascin actin-bundling protein 2, retinal 1.00103
PFN1 profilin 1 0.981959
RDX radixin 0.964549
WASF3 WAS protein family, member 3 0.938795
VAV1 vav 1 guanine nucleotide exchange factor 0.938795
NFASC neurofascin 0.925604
MAG myelin associated glycoprotein 0.917177
ELMO2 engulfment and cell motility 2 0.914376
NEXN nexilin (F actin binding protein) 0.908785
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.905531
PFN2 profilin 2 0.89672
WASF2 WAS protein family, member 2 0.876409
PFN4 profilin family, member 4 0.873647
IQGAP1 IQ motif containing GTPase activating protein 1 0.870885
INPPL1 inositol polyphosphate phosphatase-like 1 0.826336
LRRC16A leucine rich repeat containing 16A 0.823123
ARHGAP31 Rho GTPase activating protein 31 0.808441
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.804772
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.790106
GRB2 growth factor receptor-bound protein 2 0.784156
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.776384
FMN1 formin 1 0.775928
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.766349
CNTN2 contactin 2 (axonal) 0.763617
ZYX zyxin 0.761342
ACHE acetylcholinesterase (Yt blood group) 0.756345
TPM1 tropomyosin 1 (alpha) 0.753623
SPATA13 spermatogenesis associated 13 0.745025
ARHGAP1 Rho GTPase activating protein 1 0.744122
ILK integrin-linked kinase 0.744122
VAV3 vav 3 guanine nucleotide exchange factor 0.736014
FLNA filamin A, alpha 0.731076
PARVB parvin, beta 0.726599
CORO1B coronin, actin binding protein, 1B 0.71857
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.708366
NGF nerve growth factor (beta polypeptide) 0.705273
DNM2 dynamin 2 0.701744
EPS8 epidermal growth factor receptor pathway substrate 8 0.699983
WASL Wiskott-Aldrich syndrome-like 0.689451
LIMK1 LIM domain kinase 1 0.688139
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.687264
ANK1 ankyrin 1, erythrocytic 0.68639
GSN gelsolin 0.681591
FGD3 FYVE, RhoGEF and PH domain containing 3 0.676803
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 0.672894
EGFR epidermal growth factor receptor 0.671159
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.669425
ARHGAP35 Rho GTPase activating protein 35 0.668992
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.655602
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.65345
BCAR1 breast cancer anti-estrogen resistance 1 0.647003
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.643572
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.642286
ARHGAP18 Rho GTPase activating protein 18 0.637578
FHOD1 formin homology 2 domain containing 1 0.635868
STARD13 StAR-related lipid transfer (START) domain containing 13 0.63544
DNAH8 dynein, axonemal, heavy chain 8 0.635013
ACTB actin, beta 0.632878
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.632024
IQGAP2 IQ motif containing GTPase activating protein 2 0.626057
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.624781
PLCG1 phospholipase C, gamma 1 0.623079
ACTG1 actin gamma 1 0.623079
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 0.622229
RHOQ ras homolog family member Q 0.620104
FRMD1 FERM domain containing 1 0.616285
EVL Enah/Vasp-like 0.612048
NCKIPSD NCK interacting protein with SH3 domain 0.611625
MYLK myosin light chain kinase 0.609086
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.605284
CD44 CD44 molecule (Indian blood group) 0.60444
LAYN layilin 0.602331
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.601909
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.59896
ELMO3 engulfment and cell motility 3 0.592652
SSH1 slingshot protein phosphatase 1 0.589714
AMPH amphiphysin 0.588875
PLCD1 phospholipase C, delta 1 0.588037
DIAPH3 diaphanous-related formin 3 0.587618
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 0.585523
CYTH1 cytohesin 1 0.579669
PLD2 phospholipase D2 0.576747
CSF1 colony stimulating factor 1 (macrophage) 0.575495
SPRY2 sprouty homolog 2 (Drosophila) 0.564262
SH3YL1 SH3 and SYLF domain containing 1 0.560528
TJP1 tight junction protein 1 0.557629
RAB34 RAB34, member RAS oncogene family 0.557214
CDKN2A cyclin-dependent kinase inhibitor 2A 0.555145
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.552251
SEBOX SEBOX homeobox 0.550186
MYO18A myosin XVIIIA 0.54936
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.548535
DOCK5 dedicator of cytokinesis 5 0.547297
ARF1 ADP-ribosylation factor 1 0.545648
S1PR1 sphingosine-1-phosphate receptor 1 0.543176
NCK2 NCK adaptor protein 2 0.54194
RHOB ras homolog family member B 0.539472
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.53906
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.538649
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.538649
ANKRD28 ankyrin repeat domain 28 0.535772
CORO1C coronin, actin binding protein, 1C 0.534951
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.531258
JUN jun proto-oncogene 0.529618
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 0.527979
EPB41 erythrocyte membrane protein band 4.1 0.523067
NCK1 NCK adaptor protein 1 0.50107
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.500258
BCAR3 breast cancer anti-estrogen resistance 3 0.500258
ITGB1BP1 integrin beta 1 binding protein 1 0.49499
SYK spleen tyrosine kinase 0.492561
DGKZ diacylglycerol kinase, zeta 0.492561
NRG4 neuregulin 4 0.492157
KPTN kaptin (actin binding protein) 0.489731
PALLD palladin, cytoskeletal associated protein 0.488115
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.486904
PLEK2 pleckstrin 2 0.4865
MARCKS myristoylated alanine-rich protein kinase C substrate 0.483676
PLAU plasminogen activator, urokinase 0.478843
ABI1 abl-interactor 1 0.47844
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.478038
ARF5 ADP-ribosylation factor 5 0.476027
GMFG glia maturation factor, gamma 0.476027
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.475625
TESC tescalcin 0.473617
SCYL3 SCY1-like 3 (S. cerevisiae) 0.472011
HRAS Harvey rat sarcoma viral oncogene homolog 0.472011
FYB FYN binding protein 0.471609
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.471208
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.469203
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.468001
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.464397
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.464397
EFS embryonal Fyn-associated substrate 0.455214
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.454816
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.452029
CD2AP CD2-associated protein 0.451233
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.445672
EPS8L3 EPS8-like 3 0.444482
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.441708
MYO9B myosin IXB 0.438937
IGF1 insulin-like growth factor 1 (somatomedin C) 0.438146
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.435775
CTNND1 catenin (cadherin-associated protein), delta 1 0.434196
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.430253
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.424353
AKIRIN1 akirin 1 0.42396
TRIP10 thyroid hormone receptor interactor 10 0.42082
NCKAP1 NCK-associated protein 1 0.418468
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.413773
LIMA1 LIM domain and actin binding 1 0.41221
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.41182
GAS7 growth arrest-specific 7 0.41182
PLS3 plastin 3 0.410649
MAPK8 mitogen-activated protein kinase 8 0.409869
FYN FYN proto-oncogene, Src family tyrosine kinase 0.409089
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.408699
OCRL oculocerebrorenal syndrome of Lowe 0.40675
ABHD12B abhydrolase domain containing 12B 0.400916
CALD1 caldesmon 1 0.400916
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.399363
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.399363
RET ret proto-oncogene 0.397035
GLDN gliomedin 0.395485
RND1 Rho family GTPase 1 0.39471
WWC2 WW and C2 domain containing 2 0.393162
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.392388
RAP2B RAP2B, member of RAS oncogene family 0.392388
ERBB2 erb-b2 receptor tyrosine kinase 2 0.392001
PLS1 plastin 1 0.390455
CD302 CD302 molecule 0.390068
CD82 CD82 molecule 0.388137
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.388137
CDH5 cadherin 5, type 2 (vascular endothelium) 0.387365
PRX periaxin 0.386593
MBP myelin basic protein 0.385822
SAR1A secretion associated, Ras related GTPase 1A 0.385436
ARF3 ADP-ribosylation factor 3 0.385051
MMP9 matrix metallopeptidase 9 0.383509
INSR insulin receptor 0.382354
RAB1B RAB1B, member RAS oncogene family 0.381969
GRB7 growth factor receptor-bound protein 7 0.379276
DOCK4 dedicator of cytokinesis 4 0.378507
INS insulin 0.377354
MYO6 myosin VI 0.376202
TNC tenascin C 0.375434
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.374666
CFL1 cofilin 1 (non-muscle) 0.373132
DOCK8 dedicator of cytokinesis 8 0.371982
TMEM97 transmembrane protein 97 0.367771
MYO10 myosin X 0.366241
PTPN20 protein tyrosine phosphatase, non-receptor type 20 0.365095
PTEN phosphatase and tensin homolog 0.363567
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.361659
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.359752
MTSS1 metastasis suppressor 1 0.359371
SOS1 son of sevenless homolog 1 (Drosophila) 0.358609
MYO1B myosin IB 0.357847
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.357086
ACTN4 actinin, alpha 4 0.355944
VAMP3 vesicle-associated membrane protein 3 0.355944
NHSL2 NHS-like 2 0.353282
NHSL1 NHS-like 1 0.353282
MAPK4 mitogen-activated protein kinase 4 0.352522
DBNL drebrin-like 0.351382
ICAM1 intercellular adhesion molecule 1 0.349484
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.348725
SYP synaptophysin 0.348346
TIAM2 T-cell lymphoma invasion and metastasis 2 0.345692
SASH1 SAM and SH3 domain containing 1 0.344556
MET MET proto-oncogene, receptor tyrosine kinase 0.341151
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.336241
CSK c-src tyrosine kinase 0.336241
NCAM1 neural cell adhesion molecule 1 0.335487
PI3 peptidase inhibitor 3, skin-derived 0.33511
FAT1 FAT atypical cadherin 1 0.333979
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.333602
UGT8 UDP glycosyltransferase 8 0.333225
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.332472
TESK1 testis-specific kinase 1 0.332095
ADGRF5 adhesion G protein-coupled receptor F5 0.330966
CDK20 cyclin-dependent kinase 20 0.330966
WASF1 WAS protein family, member 1 0.329837
GDNF glial cell derived neurotrophic factor 0.329837
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.329084
EFHD2 EF-hand domain family, member D2 0.329084
F2R coagulation factor II (thrombin) receptor 0.327581
VEGFA vascular endothelial growth factor A 0.319702
ICAM5 intercellular adhesion molecule 5, telencephalin 0.318953
THBS1 thrombospondin 1 0.31783
NRP1 neuropilin 1 0.317456
COMMD5 COMM domain containing 5 0.317082
FGD1 FYVE, RhoGEF and PH domain containing 1 0.316708
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.314839
GPM6A glycoprotein M6A 0.312224
KNG1 kininogen 1 0.311851
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.309986
EPS8L2 EPS8-like 2 0.309613
TYRO3 TYRO3 protein tyrosine kinase 0.307749
PODXL podocalyxin-like 0.305888
RRAS related RAS viral (r-ras) oncogene homolog 0.304771
CYTH4 cytohesin 4 0.30254
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing 0.30254
EPS8L1 EPS8-like 1 0.300682
TF transferrin 0.300311
CXCL12 chemokine (C-X-C motif) ligand 12 0.29994
LGALS3 lectin, galactoside-binding, soluble, 3 0.298455
ACTA1 actin, alpha 1, skeletal muscle 0.298084
DIAPH1 diaphanous-related formin 1 0.297342
ATE1 arginyltransferase 1 0.296601
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.295489
MTMR9 myotubularin related protein 9 0.295119
PARD6A par-6 family cell polarity regulator alpha 0.295119
DLC1 DLC1 Rho GTPase activating protein 0.294378
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.291417
ADGRE1 adhesion G protein-coupled receptor E1 0.290678
AIF1 allograft inflammatory factor 1 0.290308
MSH6 mutS homolog 6 0.290308
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.290308
FGD5 FYVE, RhoGEF and PH domain containing 5 0.289569
FAM215A family with sequence similarity 215, member A (non-protein coding) 0.288091
BAIAP2L1 BAI1-associated protein 2-like 1 0.284769
DGKA diacylglycerol kinase, alpha 80kDa 0.284401
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.282926
PRKD1 protein kinase D1 0.281821
MICALL2 MICAL-like 2 0.281453
CALCA calcitonin-related polypeptide alpha 0.279245
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 0.278141
SYNJ2 synaptojanin 2 0.277038
RAB5A RAB5A, member RAS oncogene family 0.276671
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 0.276304
MMP2 matrix metallopeptidase 2 0.272267
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.270068
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.268969
MIR197 microRNA 197 0.268237
LAMB2 laminin, beta 2 (laminin S) 0.267871
NEBL nebulette 0.267871
FGF1 fibroblast growth factor 1 (acidic) 0.267139
PTK2 protein tyrosine kinase 2 0.266774
RICTOR RPTOR independent companion of MTOR, complex 2 0.266774
RALGDS ral guanine nucleotide dissociation stimulator 0.265311
NRCAM neuronal cell adhesion molecule 0.264946
TGFB1 transforming growth factor, beta 1 0.264581
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.264215
SNAP23 synaptosomal-associated protein, 23kDa 0.264215
FLNB filamin B, beta 0.264215
PLXNB1 plexin B1 0.263485
NISCH nischarin 0.26239
TPRKB TP53RK binding protein 0.260202
ADAP1 ArfGAP with dual PH domains 1 0.259837
CAV1 caveolin 1, caveolae protein, 22kDa 0.259109
PTPRD protein tyrosine phosphatase, receptor type, D 0.258381
CLASP2 cytoplasmic linker associated protein 2 0.256561
NT5E 5'-nucleotidase, ecto (CD73) 0.255107
FGF2 fibroblast growth factor 2 (basic) 0.254017
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.251839
CHN1 chimerin 1 0.250026
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.247854
ITGB6 integrin, beta 6 0.246407
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.246407
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.244962
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 0.244962
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.24424
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.24424
S100A4 S100 calcium binding protein A4 0.243158
BTK Bruton agammaglobulinemia tyrosine kinase 0.241716
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 0.239197
RTN4 reticulon 4 0.238119
PDE9A phosphodiesterase 9A 0.23776
EPHA2 EPH receptor A2 0.236683
CAPN2 calpain 2, (m/II) large subunit 0.235966
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.235607
ITGB5 integrin, beta 5 0.233817
ITGB4 integrin, beta 4 0.233101
NTN1 netrin 1 0.233101
EFNB2 ephrin-B2 0.232744
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.232029
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.232029
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.231672
GAP43 growth associated protein 43 0.230245
SNX9 sorting nexin 9 0.229888
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.229532
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.226686
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.225976
FLNC filamin C, gamma 0.224913
ELMO1 engulfment and cell motility 1 0.224204
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.223497
WDR44 WD repeat domain 44 0.222436
CXCR2 chemokine (C-X-C motif) receptor 2 0.222083
GBP5 guanylate binding protein 5 0.221378
LMBR1 limb development membrane protein 1 0.219969
HDAC6 histone deacetylase 6 0.218914
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.217861
DCP1B decapping mRNA 1B 0.21716
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.21716
ALPPL2 alkaline phosphatase, placental-like 2 0.21646
LYN LYN proto-oncogene, Src family tyrosine kinase 0.216111
ALPL alkaline phosphatase, liver/bone/kidney 0.215761
ALPP alkaline phosphatase, placental 0.215412
LMCD1 LIM and cysteine-rich domains 1 0.214366
RIN2 Ras and Rab interactor 2 0.214366
BCHE butyrylcholinesterase 0.213322
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.212627
SH2D5 SH2 domain containing 5 0.211933
ARHGAP24 Rho GTPase activating protein 24 0.211587
NTN3 netrin 3 0.209513
ACPP acid phosphatase, prostate 0.208137
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.207794
TBC1D24 TBC1 domain family, member 24 0.207108
MYO5A myosin VA (heavy chain 12, myoxin) 0.206423
WDR26 WD repeat domain 26 0.204718
C5AR1 complement component 5a receptor 1 0.204718
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.204378
PHLDB1 pleckstrin homology-like domain, family B, member 1 0.202009
CDH13 cadherin 13 0.198991
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.198658
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.197993
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.195681
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.195025
PARD3B par-3 family cell polarity regulator beta 0.194698
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.194045
ZNF675 zinc finger protein 675 0.192746
STX4 syntaxin 4 0.191135
NF2 neurofibromin 2 (merlin) 0.190814
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.190495
GAS6 growth arrest-specific 6 0.189539
WASH7P WAS protein family homolog 7 pseudogene 0.188274
CCNG2 cyclin G2 0.18796
WDFY1 WD repeat and FYVE domain containing 1 0.187646
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 0.187333
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.18702
PLA2G1B phospholipase A2, group IB (pancreas) 0.18702
WASH6P WAS protein family homolog 6 pseudogene 0.185469
PARVG parvin, gamma 0.18516
ANXA2 annexin A2 0.18516
TNR tenascin R 0.184853
GJB1 gap junction protein, beta 1, 32kDa 0.184547
WASH1 WAS protein family homolog 1 0.183328
EFNB3 ephrin-B3 0.183328
ALB albumin 0.183025
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.182422
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.181823
PHACTR4 phosphatase and actin regulator 4 0.180339
SMPX small muscle protein, X-linked 0.179167
CCR10 chemokine (C-C motif) receptor 10 0.178588
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.178011
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.177439
RIC8A RIC8 guanine nucleotide exchange factor A 0.177439
MYH9 myosin, heavy chain 9, non-muscle 0.177154
INPP5K inositol polyphosphate-5-phosphatase K 0.174911
LGALS8 lectin, galactoside-binding, soluble, 8 0.174635
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.173273
MEGF10 multiple EGF-like-domains 10 0.173273
AQP1 aquaporin 1 (Colton blood group) 0.172735
BDNF brain-derived neurotrophic factor 0.171937
DOCK2 dedicator of cytokinesis 2 0.171673
CCDC88A coiled-coil domain containing 88A 0.171149
DVL3 dishevelled segment polarity protein 3 0.170114
GRP gastrin-releasing peptide 0.168847
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 0.168847
MYO1A myosin IA 0.167856
MCF2L MCF.2 cell line derived transforming sequence-like 0.167611
RAB10 RAB10, member RAS oncogene family 0.167611
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.167366
PTH parathyroid hormone 0.165463
RHOBTB1 Rho-related BTB domain containing 1 0.165231
MOB1B MOB kinase activator 1B 0.165231
LTBP2 latent transforming growth factor beta binding protein 2 0.164089
CADM2 cell adhesion molecule 2 0.163865
FGD4 FYVE, RhoGEF and PH domain containing 4 0.1632
EIF5A2 eukaryotic translation initiation factor 5A2 0.16298
CCDC88C coiled-coil domain containing 88C 0.162117
MTMR6 myotubularin related protein 6 0.161693
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.159856
ERBB3 erb-b2 receptor tyrosine kinase 3 0.159268
GSK3A glycogen synthase kinase 3 alpha 0.158882
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.158692
ITGB7 integrin, beta 7 0.158502
NAV3 neuron navigator 3 0.158315
WNT5A wingless-type MMTV integration site family, member 5A 0.158129
ITGB8 integrin, beta 8 0.158129
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.158129
IGSF5 immunoglobulin superfamily, member 5 0.15776
DPYSL3 dihydropyrimidinase-like 3 0.15776
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.15776
DBN1 drebrin 1 0.157397