cell fate commitment Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. (Gene Ontology, GO_0045165)
External Link http://amigo.geneontology.org/amigo/term/GO:0045165
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Genes

136 genes participating in the cell fate commitment biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACVR1 activin A receptor, type I
ARX aristaless related homeobox
ASCL1 achaete-scute family bHLH transcription factor 1
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
C17ORF96 chromosome 17 open reading frame 96
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDC73 cell division cycle 73
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
DLL4 delta-like 4 (Drosophila)
DLX1 distal-less homeobox 1
DLX2 distal-less homeobox 2
EPAS1 endothelial PAS domain protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FEZF2 FEZ family zinc finger 2
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FOXC2 forkhead box C2
FOXN4 forkhead box N4
FOXP3 forkhead box P3
GAP43 growth associated protein 43
GAS1 growth arrest-specific 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GBX1 gastrulation brain homeobox 1
GCM1 glial cells missing homolog 1 (Drosophila)
GDF7 growth differentiation factor 7
GFI1 growth factor independent 1 transcription repressor
GSX1 GS homeobox 1
GSX2 GS homeobox 2
HES5 hes family bHLH transcription factor 5
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IHH indian hedgehog
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
IRF4 interferon regulatory factor 4
JAG2 jagged 2
KDR kinase insert domain receptor
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LHX6 LIM homeobox 6
MEN1 multiple endocrine neoplasia I
MITF microphthalmia-associated transcription factor
MYF5 myogenic factor 5
MYF6 myogenic factor 6 (herculin)
MYOD1 myogenic differentiation 1
MYOG myogenin (myogenic factor 4)
NANOG Nanog homeobox
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
NEUROG1 neurogenin 1
NEUROG2 neurogenin 2
NKX2-1 NK2 homeobox 1
NKX2-2 NK2 homeobox 2
NKX2-5 NK2 homeobox 5
NOTCH1 notch 1
NOTCH3 notch 3
NR2E1 nuclear receptor subfamily 2, group E, member 1
NRG1 neuregulin 1
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
ONECUT1 one cut homeobox 1
ONECUT2 one cut homeobox 2
OTX2 orthodenticle homeobox 2
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAX3 paired box 3
PAX6 paired box 6
PAX7 paired box 7
PITX1 paired-like homeodomain 1
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PRDM1 PR domain containing 1, with ZNF domain
PRDM14 PR domain containing 14
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTF1A pancreas specific transcription factor, 1a
RAG2 recombination activating gene 2
RARA retinoic acid receptor, alpha
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RUNX2 runt-related transcription factor 2
SATB2 SATB homeobox 2
SFRP1 secreted frizzled-related protein 1
SHH sonic hedgehog
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SOX12 SRY (sex determining region Y)-box 12
SOX2 SRY (sex determining region Y)-box 2
SOX5 SRY (sex determining region Y)-box 5
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAL1 T-cell acute lymphocytic leukemia 1
TBR1 T-box, brain, 1
TBX1 T-box 1
TBX19 T-box 19
TBX3 T-box 3
TCF3 transcription factor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TLX1 T-cell leukemia homeobox 1
TP53 tumor protein p53
VSX2 visual system homeobox 2
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
WNT8A wingless-type MMTV integration site family, member 8A
WNT8B wingless-type MMTV integration site family, member 8B
WNT9A wingless-type MMTV integration site family, member 9A
WNT9B wingless-type MMTV integration site family, member 9B
WT1 Wilms tumor 1
ZFPM1 zinc finger protein, FOG family member 1