cell cycle checkpoint Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction. (Gene Ontology, GO_0000075)
External Link http://amigo.geneontology.org/amigo/term/GO:0000075
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Genes

152 genes participating in the cell cycle checkpoint biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
APC adenomatous polyposis coli
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
AURKB aurora kinase B
BABAM1 BRISC and BRCA1 A complex member 1
BCL2L1 BCL2-like 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRSK1 BR serine/threonine kinase 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C10ORF90 chromosome 10 open reading frame 90
CASC5 cancer susceptibility candidate 5
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE2 cyclin E2
CCNG1 cyclin G1
CCNG2 cyclin G2
CDC14B cell division cycle 14B
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CENPF centromere protein F, 350/400kDa
CEP63 centrosomal protein 63kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CLOCK clock circadian regulator
CLSPN claspin
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
DCLRE1B DNA cross-link repair 1B
DLG1 discs, large homolog 1 (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F1 E2F transcription factor 1
FAM175A family with sequence similarity 175, member A
FANCG Fanconi anemia, complementation group G
FBXO31 F-box protein 31
FBXO6 F-box protein 6
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GIGYF2 GRB10 interacting GYF protein 2
H2AFX H2A histone family, member X
HINFP histone H4 transcription factor
HMGA2 high mobility group AT-hook 2
HORMAD1 HORMA domain containing 1
HRAS Harvey rat sarcoma viral oncogene homolog
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
IER3 immediate early response 3
INTS3 integrator complex subunit 3
INTS7 integrator complex subunit 7
KLHL22 kelch-like family member 22
KNTC1 kinetochore associated 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBD4 methyl-CpG binding domain protein 4
MDC1 mediator of DNA-damage checkpoint 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH2 mutS homolog 2
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NBN nibrin
NEK11 NIMA-related kinase 11
NEK6 NIMA-related kinase 6
PEA15 phosphoprotein enriched in astrocytes 15
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PLK5 polo-like kinase 5
PRCC papillary renal cell carcinoma (translocation-associated)
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RFWD3 ring finger and WD repeat domain 3
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA4 replication protein A4, 30kDa
RPS27L ribosomal protein S27-like
RPS6 ribosomal protein S6
SETMAR SET domain and mariner transposase fusion gene
SMC1A structural maintenance of chromosomes 1A
SPDL1 spindle apparatus coiled-coil protein 1
STIL SCL/TAL1 interrupting locus
STRA8 stimulated by retinoic acid 8
SYF2 SYF2 pre-mRNA-splicing factor
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TEX14 testis expressed 14
TGFB1 transforming growth factor, beta 1
TICRR TOPBP1-interacting checkpoint and replication regulator
TIPIN TIMELESS interacting protein
TIPRL TOR signaling pathway regulator
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPR translocated promoter region, nuclear basket protein
TRRAP transformation/transcription domain-associated protein
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UIMC1 ubiquitin interaction motif containing 1
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP28 ubiquitin specific peptidase 28
WAC WW domain containing adaptor with coiled-coil
WNT9A wingless-type MMTV integration site family, member 9A
XPC xeroderma pigmentosum, complementation group C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF207 zinc finger protein 207
ZNF830 zinc finger protein 830
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein