celecoxib-922 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the celecoxib-922 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
AKAP13 A kinase (PRKA) anchor protein 13
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARL4C ADP-ribosylation factor-like 4C
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF3 activating transcription factor 3
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BHLHE40 basic helix-loop-helix family, member e40
CADM4 cell adhesion molecule 4
CAMTA2 calmodulin binding transcription activator 2
CCNJL cyclin J-like
CEMIP cell migration inducing protein, hyaluronan binding
CFAP45 cilia and flagella associated protein 45
CLEC10A C-type lectin domain family 10, member A
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTNA dystrobrevin, alpha
EGR1 early growth response 1
EPN2 epsin 2
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GLUD2 glutamate dehydrogenase 2
GPATCH2L G patch domain containing 2-like
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AE histone cluster 1, H2ae
HIST1H2AK histone cluster 1, H2ak
HIST1H3B histone cluster 1, H3b
HIST1H4H histone cluster 1, H4h
HSDL2 hydroxysteroid dehydrogenase like 2
HSF4 heat shock transcription factor 4
HYAL4 hyaluronoglucosaminidase 4
IRF1 interferon regulatory factor 1
ITGB4 integrin, beta 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KANSL3 KAT8 regulatory NSL complex subunit 3
KRTAP1-3 keratin associated protein 1-3
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LRRC40 leucine rich repeat containing 40
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MED25 mediator complex subunit 25
MINK1 misshapen-like kinase 1
MMP19 matrix metallopeptidase 19
MTMR1 myotubularin related protein 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MXD4 MAX dimerization protein 4
NF1 neurofibromin 1
NGLY1 N-glycanase 1
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NPTX1 neuronal pentraxin I
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
PAX4 paired box 4
PBX2 pre-B-cell leukemia homeobox 2
PCDH12 protocadherin 12
PDGFB platelet-derived growth factor beta polypeptide
PEX7 peroxisomal biogenesis factor 7
PHC3 polyhomeotic homolog 3 (Drosophila)
PLTP phospholipid transfer protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM12 PR domain containing 12
PRDX2 peroxiredoxin 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKD3 protein kinase D3
PTHLH parathyroid hormone-like hormone
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNDC3B RUN domain containing 3B
SAP30 Sin3A-associated protein, 30kDa
SIDT1 SID1 transmembrane family, member 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX13 sorting nexin 13
SRRT serrate, RNA effector molecule
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SURF1 surfeit 1
TBC1D2 TBC1 domain family, member 2
TMEM63A transmembrane protein 63A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM23 tripartite motif containing 23
TRIO trio Rho guanine nucleotide exchange factor
TTC28 tetratricopeptide repeat domain 28
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
ZNF783 zinc finger family member 783
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BTBD2 BTB (POZ) domain containing 2
C14ORF93 chromosome 14 open reading frame 93
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC85C coiled-coil domain containing 85C
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP85 centrosomal protein 85kDa
CORO1A coronin, actin binding protein, 1A
CORT cortistatin
CYB5R1 cytochrome b5 reductase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHDDS dehydrodolichyl diphosphate synthase
DTX4 deltex 4, E3 ubiquitin ligase
EMC7 ER membrane protein complex subunit 7
EPHB3 EPH receptor B3
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
F8 coagulation factor VIII, procoagulant component
FAM114A2 family with sequence similarity 114, member A2
FAM118A family with sequence similarity 118, member A
FAM188A family with sequence similarity 188, member A
FASTKD1 FAST kinase domains 1
FMO4 flavin containing monooxygenase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GLTP glycolipid transfer protein
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HPS6 Hermansky-Pudlak syndrome 6
HSPA2 heat shock 70kDa protein 2
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
JMJD4 jumonji domain containing 4
KIAA0125 KIAA0125
KIAA0141 KIAA0141
KRT15 keratin 15, type I
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP9 microtubule-associated protein 9
MAPK3 mitogen-activated protein kinase 3
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHA5 protocadherin alpha 5
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHACTR4 phosphatase and actin regulator 4
PIBF1 progesterone immunomodulatory binding factor 1
PLA2G15 phospholipase A2, group XV
POLH polymerase (DNA directed), eta
PRPH peripherin
PSKH1 protein serine kinase H1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBL1 retinoblastoma-like 1
RNF39 ring finger protein 39
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SAMD9 sterile alpha motif domain containing 9
SART1 squamous cell carcinoma antigen recognized by T cells
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC12A9 solute carrier family 12, member 9
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
SOAT1 sterol O-acyltransferase 1
STX5 syntaxin 5
TESK1 testis-specific kinase 1
THOP1 thimet oligopeptidase 1
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
WDR25 WD repeat domain 25
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC11 zinc finger, DHHC-type containing 11
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF226 zinc finger protein 226
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF787 zinc finger protein 787