cefsulodin-3328 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefsulodin-3328 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDOB aldolase B, fructose-bisphosphate
ARHGAP26 Rho GTPase activating protein 26
ATF6 activating transcription factor 6
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AUTS2 autism susceptibility candidate 2
BTF3P11 basic transcription factor 3 pseudogene 11
CAMKV CaM kinase-like vesicle-associated
CARD14 caspase recruitment domain family, member 14
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD96 CD96 molecule
CELA2A chymotrypsin-like elastase family, member 2A
CNGB1 cyclic nucleotide gated channel beta 1
CNR2 cannabinoid receptor 2 (macrophage)
COL10A1 collagen, type X, alpha 1
CXCL6 chemokine (C-X-C motif) ligand 6
CXORF21 chromosome X open reading frame 21
DEAF1 DEAF1 transcription factor
DOK5 docking protein 5
ELSPBP1 epididymal sperm binding protein 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLJ42627 uncharacterized LOC645644
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FXYD5 FXYD domain containing ion transport regulator 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAS7 growth arrest-specific 7
GH1 growth hormone 1
GP5 glycoprotein V (platelet)
GPR3 G protein-coupled receptor 3
GRK4 G protein-coupled receptor kinase 4
GSK3A glycogen synthase kinase 3 alpha
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCG4B HLA complex group 4B (non-protein coding)
HGD homogentisate 1,2-dioxygenase
HIST1H1T histone cluster 1, H1t
HOXA10 homeobox A10
IGLJ3 immunoglobulin lambda joining 3
IL1RN interleukin 1 receptor antagonist
IL7R interleukin 7 receptor
ING1 inhibitor of growth family, member 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KDM4B lysine (K)-specific demethylase 4B
KRT85 keratin 85, type II
KSR1 kinase suppressor of ras 1
LEF1 lymphoid enhancer-binding factor 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTBP2 latent transforming growth factor beta binding protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MX1 MX dynamin-like GTPase 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOX1 NADPH oxidase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OTOR otoraplin
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX8 paired box 8
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE9A phosphodiesterase 9A
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RHEB Ras homolog enriched in brain
RIMS2 regulating synaptic membrane exocytosis 2
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIPA1 signal-induced proliferation-associated 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNTG1 syntrophin, gamma 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTBN1 spectrin, beta, non-erythrocytic 1
STATH statherin
STMN1 stathmin 1
SYNDIG1 synapse differentiation inducing 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEF thyrotrophic embryonic factor
TIMP3 TIMP metallopeptidase inhibitor 3
TLDC1 TBC/LysM-associated domain containing 1
TRIM68 tripartite motif containing 68
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZC3H13 zinc finger CCCH-type containing 13
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF407 zinc finger protein 407
ZNF589 zinc finger protein 589
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHD1 bromo adjacent homology domain containing 1
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC176 coiled-coil domain containing 176
CCNK cyclin K
CGA glycoprotein hormones, alpha polypeptide
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COPZ2 coatomer protein complex, subunit zeta 2
CRY2 cryptochrome circadian clock 2
CTNND2 catenin (cadherin-associated protein), delta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DIXDC1 DIX domain containing 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
EXOC6B exocyst complex component 6B
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FLCN folliculin
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMEB1 glucocorticoid modulatory element binding protein 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AL histone cluster 1, H2al
HIST2H2AA3 histone cluster 2, H2aa3
IL17RA interleukin 17 receptor A
INADL InaD-like (Drosophila)
KCTD7 potassium channel tetramerization domain containing 7
KLF11 Kruppel-like factor 11
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
LIME1 Lck interacting transmembrane adaptor 1
LRRC20 leucine rich repeat containing 20
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MTCP1 mature T-cell proliferation 1
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLXNA3 plexin A3
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRODH proline dehydrogenase (oxidase) 1
RAB30 RAB30, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIN2 Ras and Rab interactor 2
RPL10L ribosomal protein L10-like
RRAGB Ras-related GTP binding B
SCAI suppressor of cancer cell invasion
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2B3 SH2B adaptor protein 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPTBN2 spectrin, beta, non-erythrocytic 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARP TCR gamma alternate reading frame protein
TDRD1 tudor domain containing 1
TLR5 toll-like receptor 5
TMEM180 transmembrane protein 180
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBXN6 UBX domain protein 6
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
ZBTB44 zinc finger and BTB domain containing 44
ZNF276 zinc finger protein 276
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF747 zinc finger protein 747