cefoxitin-7148 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cefoxitin-7148 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACVR1B activin A receptor, type IB
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANG angiogenin, ribonuclease, RNase A family, 5
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATXN7L1 ataxin 7-like 1
BIN1 bridging integrator 1
BMP1 bone morphogenetic protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTN3A1 butyrophilin, subfamily 3, member A1
CCNA1 cyclin A1
CD22 CD22 molecule
CDH8 cadherin 8, type 2
CDKL3 cyclin-dependent kinase-like 3
CHMP6 charged multivesicular body protein 6
CNTNAP2 contactin associated protein-like 2
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DCAKD dephospho-CoA kinase domain containing
DENND4A DENN/MADD domain containing 4A
DHODH dihydroorotate dehydrogenase (quinone)
DUSP10 dual specificity phosphatase 10
EFNA5 ephrin-A5
ELOVL5 ELOVL fatty acid elongase 5
EPHB2 EPH receptor B2
ERCC1 excision repair cross-complementation group 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV1 ets variant 1
FKBP15 FK506 binding protein 15, 133kDa
FOXG1 forkhead box G1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FUZ fuzzy planar cell polarity protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPX2 glutathione peroxidase 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAPLN1 hyaluronan and proteoglycan link protein 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2BO histone cluster 1, H2bo
HNF1B HNF1 homeobox B
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOMER3 homer scaffolding protein 3
HOXA4 homeobox A4
HSF2 heat shock transcription factor 2
IFIH1 interferon induced with helicase C domain 1
IFT74 intraflagellar transport 74
IGFBP3 insulin-like growth factor binding protein 3
INF2 inverted formin, FH2 and WH2 domain containing
ITGA10 integrin, alpha 10
KRIT1 KRIT1, ankyrin repeat containing
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAPK12 mitogen-activated protein kinase 12
MAST4 microtubule associated serine/threonine kinase family member 4
MDFI MyoD family inhibitor
MFSD6 major facilitator superfamily domain containing 6
MLYCD malonyl-CoA decarboxylase
MVK mevalonate kinase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK myosin light chain kinase
MZF1 myeloid zinc finger 1
NF2 neurofibromin 2 (merlin)
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OGDHL oxoglutarate dehydrogenase-like
OPTN optineurin
PAIP2B poly(A) binding protein interacting protein 2B
PLK4 polo-like kinase 4
POLH polymerase (DNA directed), eta
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PTBP3 polypyrimidine tract binding protein 3
RAB2A RAB2A, member RAS oncogene family
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNF126P1 ring finger protein 126 pseudogene 1
SCARA3 scavenger receptor class A, member 3
SCARB1 scavenger receptor class B, member 1
SH3BP2 SH3-domain binding protein 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SRD5A3 steroid 5 alpha-reductase 3
TMEM80 transmembrane protein 80
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRAF3IP2 TRAF3 interacting protein 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCL vinculin
VWA8 von Willebrand factor A domain containing 8
WDR1 WD repeat domain 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF467 zinc finger protein 467
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABI1 abl-interactor 1
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANOS1 anosmin 1
ANXA10 annexin A10
ARID4A AT rich interactive domain 4A (RBP1-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C1ORF106 chromosome 1 open reading frame 106
C2CD5 C2 calcium-dependent domain containing 5
C2ORF42 chromosome 2 open reading frame 42
C5ORF15 chromosome 5 open reading frame 15
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CCRL2 chemokine (C-C motif) receptor-like 2
CD70 CD70 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP170B centrosomal protein 170B
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRYL1 crystallin, lambda 1
DCLRE1A DNA cross-link repair 1A
DGKD diacylglycerol kinase, delta 130kDa
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E4F1 E4F transcription factor 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM222B family with sequence similarity 222, member B
FBXW12 F-box and WD repeat domain containing 12
FOXJ2 forkhead box J2
GLCE glucuronic acid epimerase
GOLGA3 golgin A3
HIST1H3B histone cluster 1, H3b
INCENP inner centromere protein antigens 135/155kDa
IRF6 interferon regulatory factor 6
IRF9 interferon regulatory factor 9
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0232 KIAA0232
KIAA1551 KIAA1551
KIN Kin17 DNA and RNA binding protein
KPNA4 karyopherin alpha 4 (importin alpha 3)
LINS lines homolog (Drosophila)
LY6E lymphocyte antigen 6 complex, locus E
MAN2B2 mannosidase, alpha, class 2B, member 2
MANBA mannosidase, beta A, lysosomal
MB myoglobin
MELK maternal embryonic leucine zipper kinase
MGC12488
MITF microphthalmia-associated transcription factor
MKS1 Meckel syndrome, type 1
MMP13 matrix metallopeptidase 13
MON1B MON1 secretory trafficking family member B
NAP1L3 nucleosome assembly protein 1-like 3
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL6 nucleolar protein 6 (RNA-associated)
NRSN2 neurensin 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PALB2 partner and localizer of BRCA2
PARD6A par-6 family cell polarity regulator alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRPF8 pre-mRNA processing factor 8
PTK7 protein tyrosine kinase 7 (inactive)
RARS arginyl-tRNA synthetase
RBL1 retinoblastoma-like 1
RHOC ras homolog family member C
RPA2 replication protein A2, 32kDa
RPAP2 RNA polymerase II associated protein 2
RPL7A ribosomal protein L7a
RUVBL1 RuvB-like AAA ATPase 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERTAD3 SERTA domain containing 3
SFMBT1 Scm-like with four mbt domains 1
SIX1 SIX homeobox 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX15 sorting nexin 15
SOD3 superoxide dismutase 3, extracellular
STX17 syntaxin 17
TAGLN3 transgelin 3
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TMOD3 tropomodulin 3 (ubiquitous)
TNNI3 troponin I type 3 (cardiac)
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
TULP4 tubby like protein 4
UNG uracil-DNA glycosylase
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZFP36 ZFP36 ring finger protein
ZMYM3 zinc finger, MYM-type 3
ZNF175 zinc finger protein 175
ZNF189 zinc finger protein 189
ZSCAN5A zinc finger and SCAN domain containing 5A