cefoxitin-3477 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the cefoxitin-3477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARNT aryl hydrocarbon receptor nuclear translocator
ATF7IP activating transcription factor 7 interacting protein
BTBD7 BTB (POZ) domain containing 7
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
COMT catechol-O-methyltransferase
CUEDC1 CUE domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
E2F4 E2F transcription factor 4, p107/p130-binding
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAXDC2 fatty acid hydroxylase domain containing 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAS7 growth arrest-specific 7
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GM2A GM2 ganglioside activator
GYG2 glycogenin 2
HAP1 huntingtin-associated protein 1
HBS1L HBS1-like translational GTPase
HDAC7 histone deacetylase 7
HIST1H1E histone cluster 1, H1e
HOXC10 homeobox C10
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
ING2 inhibitor of growth family, member 2
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD7 potassium channel tetramerization domain containing 7
KITLG KIT ligand
KREMEN2 kringle containing transmembrane protein 2
LAMB3 laminin, beta 3
LHX6 LIM homeobox 6
LMNA lamin A/C
LTBP2 latent transforming growth factor beta binding protein 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCF2L MCF.2 cell line derived transforming sequence-like
MEG3 maternally expressed 3 (non-protein coding)
MOCS1 molybdenum cofactor synthesis 1
MZF1 myeloid zinc finger 1
NCOA2 nuclear receptor coactivator 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGLY1 N-glycanase 1
NIPAL3 NIPA-like domain containing 3
NRL neural retina leucine zipper
NRSN2 neurensin 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAOX polyamine oxidase (exo-N4-amino)
PAX5 paired box 5
PCDH9 protocadherin 9
PCSK6 proprotein convertase subtilisin/kexin type 6
PIDD1 p53-induced death domain protein 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP4R4 protein phosphatase 4, regulatory subunit 4
PSD4 pleckstrin and Sec7 domain containing 4
PVRL3 poliovirus receptor-related 3
PXN paxillin
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM19 RNA binding motif protein 19
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
RIN2 Ras and Rab interactor 2
RNF19B ring finger protein 19B
RNF2 ring finger protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A8 S100 calcium binding protein A8
SH2B1 SH2B adaptor protein 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNN stannin
SOS2 son of sevenless homolog 2 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STX7 syntaxin 7
TACSTD2 tumor-associated calcium signal transducer 2
TBX19 T-box 19
TDRKH tudor and KH domain containing
TEX261 testis expressed 261
TGFB2 transforming growth factor, beta 2
TIMELESS timeless circadian clock
TPMT thiopurine S-methyltransferase
TRAF2 TNF receptor-associated factor 2
TREX1 three prime repair exonuclease 1
UBE3A ubiquitin protein ligase E3A
WASL Wiskott-Aldrich syndrome-like
WDR55 WD repeat domain 55
WNT10B wingless-type MMTV integration site family, member 10B
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC14 zinc finger, DHHC-type containing 14
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTL8 actin-like 8
ADAM15 ADAM metallopeptidase domain 15
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALS2CL ALS2 C-terminal like
ATG2A autophagy related 2A
BAG4 BCL2-associated athanogene 4
BEX4 brain expressed, X-linked 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
C22ORF29 chromosome 22 open reading frame 29
C2ORF54 chromosome 2 open reading frame 54
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC121 coiled-coil domain containing 121
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CENPJ centromere protein J
CENPT centromere protein T
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAL4 dynein, axonemal, light chain 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAM63A family with sequence similarity 63, member A
FCHO1 FCH domain only 1
FER fer (fps/fes related) tyrosine kinase
FRK fyn-related Src family tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPATCH3 G patch domain containing 3
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HPS6 Hermansky-Pudlak syndrome 6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ICK intestinal cell (MAK-like) kinase
IPO8 importin 8
IREB2 iron-responsive element binding protein 2
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIFAP3 kinesin-associated protein 3
LOC390998 ribosomal protein L10 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MPI mannose phosphate isomerase
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NCS1 neuronal calcium sensor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NEK11 NIMA-related kinase 11
NT5E 5'-nucleotidase, ecto (CD73)
NXPH4 neurexophilin 4
ODF2 outer dense fiber of sperm tails 2
PAIP2B poly(A) binding protein interacting protein 2B
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLH polymerase (DNA directed), eta
PRSS22 protease, serine, 22
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB30 RAB30, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RANBP17 RAN binding protein 17
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC46A3 solute carrier family 46, member 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
THRAP3 thyroid hormone receptor associated protein 3
TMC5 transmembrane channel-like 5
TMC7 transmembrane channel-like 7
TMEM2 transmembrane protein 2
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
USP20 ubiquitin specific peptidase 20
XAB2 XPA binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF250 zinc finger protein 250
ZNF770 zinc finger protein 770
ZSCAN26 zinc finger and SCAN domain containing 26