cefoxitin-2735 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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191 genes differentially expressed following the cefoxitin-2735 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
AMACR alpha-methylacyl-CoA racemase
AMPH amphiphysin
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPH aspartate beta-hydroxylase
BAAT bile acid CoA:amino acid N-acyltransferase
BFSP1 beaded filament structural protein 1, filensin
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C8A complement component 8, alpha polypeptide
CCKAR cholecystokinin A receptor
CD7 CD7 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEMP1 cementum protein 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLDN3 claudin 3
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL8A2 collagen, type VIII, alpha 2
CST1 cystatin SN
CTNND1 catenin (cadherin-associated protein), delta 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCLK2 doublecortin-like kinase 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DKKL1 dickkopf-like 1
EBF2 early B-cell factor 2
FAM13C family with sequence similarity 13, member C
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FGF21 fibroblast growth factor 21
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FLT4 fms-related tyrosine kinase 4
FOSL2 FOS-like antigen 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GJA8 gap junction protein, alpha 8, 50kDa
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRHL2 grainyhead-like 2 (Drosophila)
GRK4 G protein-coupled receptor kinase 4
GRM8 glutamate receptor, metabotropic 8
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXD10 homeobox D10
HRG histidine-rich glycoprotein
IGH immunoglobulin heavy locus
IGHA1 immunoglobulin heavy constant alpha 1
IGLJ3 immunoglobulin lambda joining 3
IL1RN interleukin 1 receptor antagonist
IL37 interleukin 37
JPH3 junctophilin 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT31 keratin 31, type I
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAOA monoamine oxidase A
MET MET proto-oncogene, receptor tyrosine kinase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPS18C mitochondrial ribosomal protein S18C
MTSS1 metastasis suppressor 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYO6 myosin VI
NRG1 neuregulin 1
PADI4 peptidyl arginine deiminase, type IV
PAPOLB poly(A) polymerase beta (testis specific)
PBOV1 prostate and breast cancer overexpressed 1
PICALM phosphatidylinositol binding clathrin assembly protein
PICK1 protein interacting with PRKCA 1
PNOC prepronociceptin
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRUNE2 prune homolog 2 (Drosophila)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RBP4 retinol binding protein 4, plasma
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3B submaxillary gland androgen regulated protein 3B
SNED1 sushi, nidogen and EGF-like domains 1
SPRR1A small proline-rich protein 1A
STMN3 stathmin-like 3
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM212 transmembrane protein 212
TRIO trio Rho guanine nucleotide exchange factor
WNT8B wingless-type MMTV integration site family, member 8B
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AMDHD2 amidohydrolase domain containing 2
ANKH ANKH inorganic pyrophosphate transport regulator
ARMCX4 armadillo repeat containing, X-linked 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AZI2 5-azacytidine induced 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C21ORF91 chromosome 21 open reading frame 91
C8ORF44 chromosome 8 open reading frame 44
CBX7 chromobox homolog 7
CES3 carboxylesterase 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRYGC crystallin, gamma C
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DUSP2 dual specificity phosphatase 2
EFNA3 ephrin-A3
EGR3 early growth response 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERO1LB ERO1-like beta (S. cerevisiae)
EXOSC1 exosome component 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM127B family with sequence similarity 127, member B
FAM131A family with sequence similarity 131, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FKBP9 FK506 binding protein 9, 63 kDa
GCH1 GTP cyclohydrolase 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK3P glycerol kinase 3 pseudogene
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR22 G protein-coupled receptor 22
GTF2IRD1 GTF2I repeat domain containing 1
HDAC7 histone deacetylase 7
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11RA interleukin 11 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
INPPL1 inositol polyphosphate phosphatase-like 1
IQCG IQ motif containing G
KANSL1L KAT8 regulatory NSL complex subunit 1-like
LGALS4 lectin, galactoside-binding, soluble, 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LSP1 lymphocyte-specific protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAB21L1 mab-21-like 1 (C. elegans)
MAGEH1 melanoma antigen family H1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MVP major vault protein
NBEA neurobeachin
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NINJ2 ninjurin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLAH oleoyl-ACP hydrolase
OXCT2 3-oxoacid CoA transferase 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
RETN resistin
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOH ras homolog family member H
RNF121 ring finger protein 121
RNF122 ring finger protein 122
SALL2 spalt-like transcription factor 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D4A SH2 domain containing 4A
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35F6 solute carrier family 35, member F6
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SYCP2 synaptonemal complex protein 2
TEC tec protein tyrosine kinase
TMEM209 transmembrane protein 209
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM3 tropomyosin 3
TRPS1 trichorhinophalangeal syndrome I
URM1 ubiquitin related modifier 1
USP6NL USP6 N-terminal like
VN1R1 vomeronasal 1 receptor 1
WASF3 WAS protein family, member 3
ZFHX4 zinc finger homeobox 4
ZNF225 zinc finger protein 225
ZNF34 zinc finger protein 34
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492
ZNHIT2 zinc finger, HIT-type containing 2