cefotiam-6762 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefotiam-6762 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACVR1B activin A receptor, type IB
ADAM12 ADAM metallopeptidase domain 12
ANKRD12 ankyrin repeat domain 12
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL2BP ADP-ribosylation factor-like 2 binding protein
AURKA aurora kinase A
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP8B bone morphogenetic protein 8b
BNC1 basonuclin 1
BTG2 BTG family, member 2
C11ORF30 chromosome 11 open reading frame 30
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD53 CD53 molecule
CD58 CD58 molecule
CD6 CD6 molecule
CTSS cathepsin S
CTSZ cathepsin Z
DCTN1 dynactin 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
DKFZP434C153 DKFZP434C153 protein
DPF3 D4, zinc and double PHD fingers, family 3
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFR3B EFR3 homolog B (S. cerevisiae)
EGFL7 EGF-like-domain, multiple 7
EIF5B eukaryotic translation initiation factor 5B
ERAP1 endoplasmic reticulum aminopeptidase 1
EREG epiregulin
EZR ezrin
FAM131B family with sequence similarity 131, member B
FAM134B family with sequence similarity 134, member B
FBXO11 F-box protein 11
FGF1 fibroblast growth factor 1 (acidic)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GPATCH4 G patch domain containing 4
GRSF1 G-rich RNA sequence binding factor 1
GUK1 guanylate kinase 1
GYPA glycophorin A (MNS blood group)
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H4F histone cluster 1, H4f
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IER3IP1 immediate early response 3 interacting protein 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNIP2 Kv channel interacting protein 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0226L KIAA0226-like
KIF25-AS1 KIF25 antisense RNA 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LPPR4 lipid phosphate phosphatase-related protein type 4
MCOLN3 mucolipin 3
MEF2D myocyte enhancer factor 2D
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS18C mitochondrial ribosomal protein S18C
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEB nebulin
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAZ3 ornithine decarboxylase antizyme 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7A5 olfactory receptor, family 7, subfamily A, member 5
PEX5L peroxisomal biogenesis factor 5-like
PGK1 phosphoglycerate kinase 1
POU6F1 POU class 6 homeobox 1
PPP5C protein phosphatase 5, catalytic subunit
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RARB retinoic acid receptor, beta
RGS10 regulator of G-protein signaling 10
RHEB Ras homolog enriched in brain
RPAIN RPA interacting protein
RPL10 ribosomal protein L10
RPL13 ribosomal protein L13
RPL14 ribosomal protein L14
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS3A ribosomal protein S3A
S100A13 S100 calcium binding protein A13
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SYT2 synaptotagmin II
TK2 thymidine kinase 2, mitochondrial
TM6SF1 transmembrane 6 superfamily member 1
TRAM1 translocation associated membrane protein 1
TWF1 twinfilin actin binding protein 1
VDAC3 voltage-dependent anion channel 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
YIPF4 Yip1 domain family, member 4
ZBTB20 zinc finger and BTB domain containing 20
ZC3H7B zinc finger CCCH-type containing 7B
ZFAND5 zinc finger, AN1-type domain 5
ZNF287 zinc finger protein 287
ZNF639 zinc finger protein 639
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM23 ADAM metallopeptidase domain 23
AFAP1 actin filament associated protein 1
ANXA2P3 annexin A2 pseudogene 3
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD5 ATPase family, AAA domain containing 5
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BTBD2 BTB (POZ) domain containing 2
CALCOCO1 calcium binding and coiled-coil domain 1
CAMKMT calmodulin-lysine N-methyltransferase
CASS4 Cas scaffolding protein family member 4
CBX8 chromobox homolog 8
CCNJL cyclin J-like
CDK6 cyclin-dependent kinase 6
CENPO centromere protein O
CHM choroideremia (Rab escort protein 1)
CLDN1 claudin 1
CORO1A coronin, actin binding protein, 1A
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DIXDC1 DIX domain containing 1
DSPP dentin sialophosphoprotein
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC5 exocyst complex component 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM168B family with sequence similarity 168, member B
FBXL15 F-box and leucine-rich repeat protein 15
FKBP5 FK506 binding protein 5
FRS2 fibroblast growth factor receptor substrate 2
GMPR guanosine monophosphate reductase
GOLGA8B golgin A8 family, member B
GRM4 glutamate receptor, metabotropic 4
GTPBP2 GTP binding protein 2
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HELZ helicase with zinc finger
HIST1H2BN histone cluster 1, H2bn
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGFBP4 insulin-like growth factor binding protein 4
IL36RN interleukin 36 receptor antagonist
IPO8 importin 8
LINS lines homolog (Drosophila)
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFGE8 milk fat globule-EGF factor 8 protein
MYH15 myosin, heavy chain 15
MYL9 myosin, light chain 9, regulatory
MYLIP myosin regulatory light chain interacting protein
NABP2 nucleic acid binding protein 2
NRSN2 neurensin 2
NTSR1 neurotensin receptor 1 (high affinity)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSBP2 oxysterol binding protein 2
PAX9 paired box 9
PCDH12 protocadherin 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKM pyruvate kinase, muscle
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRICKLE3 prickle homolog 3 (Drosophila)
PRSS8 protease, serine, 8
PTPRS protein tyrosine phosphatase, receptor type, S
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
SCARA3 scavenger receptor class A, member 3
SCIN scinderin
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SND1-IT1 SND1 intronic transcript 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TOM1 target of myb1 (chicken)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSKU tsukushi, small leucine rich proteoglycan
ULBP2 UL16 binding protein 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
YY2 YY2 transcription factor
ZNF222 zinc finger protein 222
ZNF778 zinc finger protein 778