cefoperazone-6323 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefoperazone-6323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACPP acid phosphatase, prostate
ACVR1B activin A receptor, type IB
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ASIC1 acid sensing (proton gated) ion channel 1
ATG10 autophagy related 10
AXIN1 axin 1
BAIAP2 BAI1-associated protein 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTC betacellulin
C16ORF59 chromosome 16 open reading frame 59
CA11 carbonic anhydrase XI
CALD1 caldesmon 1
CAPN5 calpain 5
CCDC6 coiled-coil domain containing 6
CCDC88A coiled-coil domain containing 88A
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CNTD2 cyclin N-terminal domain containing 2
CTSF cathepsin F
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAL4 dynein, axonemal, light chain 4
EFNA3 ephrin-A3
EML3 echinoderm microtubule associated protein like 3
ENG endoglin
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FLOT1 flotillin 1
GATA2 GATA binding protein 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF2I general transcription factor IIi
HNMT histamine N-methyltransferase
HOXB7 homeobox B7
HOXC11 homeobox C11
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IFFO1 intermediate filament family orphan 1
IL11 interleukin 11
IL1RL1 interleukin 1 receptor-like 1
IRAK4 interleukin-1 receptor-associated kinase 4
KLF4 Kruppel-like factor 4 (gut)
LINC00312 long intergenic non-protein coding RNA 312
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK11 mitogen-activated protein kinase 11
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OXLD1 oxidoreductase-like domain containing 1
PAPPA2 pappalysin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PEX26 peroxisomal biogenesis factor 26
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGPEP1 pyroglutamyl-peptidase I
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRSS16 protease, serine, 16 (thymus)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTPRF protein tyrosine phosphatase, receptor type, F
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANGAP1 Ran GTPase activating protein 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPH3AL rabphilin 3A-like (without C2 domains)
RPP25 ribonuclease P/MRP 25kDa subunit
SAYSD1 SAYSVFN motif domain containing 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SENP5 SUMO1/sentrin specific peptidase 5
SH3BP2 SH3-domain binding protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT5 sirtuin 5
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC39A9 solute carrier family 39, member 9
SLMO1 slowmo homolog 1 (Drosophila)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTBN1 spectrin, beta, non-erythrocytic 1
SS18 synovial sarcoma translocation, chromosome 18
SSH3 slingshot protein phosphatase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SYNJ2 synaptojanin 2
TACR1 tachykinin receptor 1
TK2 thymidine kinase 2, mitochondrial
TMEM53 transmembrane protein 53
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
TPR translocated promoter region, nuclear basket protein
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM14 tripartite motif containing 14
TRIM25 tripartite motif containing 25
TSFM Ts translation elongation factor, mitochondrial
WDR4 WD repeat domain 4
WNT10B wingless-type MMTV integration site family, member 10B
YOD1 YOD1 deubiquitinase
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF227 zinc finger protein 227

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMBRA1 autophagy/beclin-1 regulator 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANXA2P1 annexin A2 pseudogene 1
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCAS4 breast carcinoma amplified sequence 4
BDNF brain-derived neurotrophic factor
BFSP1 beaded filament structural protein 1, filensin
BNC1 basonuclin 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKL3 cyclin-dependent kinase-like 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYBA2 crystallin, beta A2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4A DENN/MADD domain containing 4A
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYSF dysferlin
E4F1 E4F transcription factor 1
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
ELP6 elongator acetyltransferase complex subunit 6
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GJC1 gap junction protein, gamma 1, 45kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BJ histone cluster 1, H2bj
HOXA2 homeobox A2
IMPAD1 inositol monophosphatase domain containing 1
IQSEC2 IQ motif and Sec7 domain 2
KIAA0894 KIAA0894 protein
KIAA1462 KIAA1462
LINC00341 long intergenic non-protein coding RNA 341
LINS lines homolog (Drosophila)
MAPK12 mitogen-activated protein kinase 12
MMP2 matrix metallopeptidase 2
MRPL44 mitochondrial ribosomal protein L44
MRPS18C mitochondrial ribosomal protein S18C
NLGN1 neuroligin 1
NLRX1 NLR family member X1
ORAI3 ORAI calcium release-activated calcium modulator 3
OSBP2 oxysterol binding protein 2
PACS1 phosphofurin acidic cluster sorting protein 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHA6 pleckstrin homology domain containing, family A member 6
POM121 POM121 transmembrane nucleoporin
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRR7 proline rich 7 (synaptic)
PTCD2 pentatricopeptide repeat domain 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASA2 RAS p21 protein activator 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
SAA4 serum amyloid A4, constitutive
SCG2 secretogranin II
SCN1B sodium channel, voltage gated, type I beta subunit
SDF2 stromal cell-derived factor 2
SECTM1 secreted and transmembrane 1
SIRT6 sirtuin 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STIM1 stromal interaction molecule 1
TAGLN3 transgelin 3
TMEM159 transmembrane protein 159
TRAPPC6A trafficking protein particle complex 6A
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
XAB2 XPA binding protein 2
ZFHX3 zinc finger homeobox 3
ZNF253 zinc finger protein 253
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF528 zinc finger protein 528
ZNF529 zinc finger protein 529
ZNF552 zinc finger protein 552
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747
ZNRD1-AS1 ZNRD1 antisense RNA 1