cefmetazole-7222 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the cefmetazole-7222 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP10B ATPase, class V, type 10B
ATP9B ATPase, class II, type 9B
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1ORF35 chromosome 1 open reading frame 35
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CHST10 carbohydrate sulfotransferase 10
CLCA1 chloride channel accessory 1
CLDN6 claudin 6
CORT cortistatin
CPD carboxypeptidase D
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DFNB31 deafness, autosomal recessive 31
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL5 ELOVL fatty acid elongase 5
FLNC filamin C, gamma
FZD7 frizzled class receptor 7
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR21 G protein-coupled receptor 21
GRM1 glutamate receptor, metabotropic 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HEG1 heart development protein with EGF-like domains 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HIST1H4D histone cluster 1, H4d
HOXC4 homeobox C4
HRH4 histamine receptor H4
HSPA1L heat shock 70kDa protein 1-like
HUS1 HUS1 checkpoint homolog (S. pombe)
IDI2-AS1 IDI2 antisense RNA 1
IGFBP5 insulin-like growth factor binding protein 5
IL11 interleukin 11
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IPO8 importin 8
JAKMIP2 janus kinase and microtubule interacting protein 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KITLG KIT ligand
LIG4 ligase IV, DNA, ATP-dependent
LINC00341 long intergenic non-protein coding RNA 341
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL3 muscleblind-like splicing regulator 3
MED25 mediator complex subunit 25
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCR2 natural cytotoxicity triggering receptor 2
NEB nebulin
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NUP50 nucleoporin 50kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PER3 period circadian clock 3
PLK4 polo-like kinase 4
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRB3 proline-rich protein BstNI subfamily 3
PRODH proline dehydrogenase (oxidase) 1
PROL1 proline rich, lacrimal 1
PSG9 pregnancy specific beta-1-glycoprotein 9
PTBP3 polypyrimidine tract binding protein 3
PTCRA pre T-cell antigen receptor alpha
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB3A RAB3A, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RTN2 reticulon 2
SCN1B sodium channel, voltage gated, type I beta subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SYBU syntabulin (syntaxin-interacting)
TGFB1 transforming growth factor, beta 1
TMEM19 transmembrane protein 19
TOP3B topoisomerase (DNA) III beta
TP73-AS1 TP73 antisense RNA 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TTC30A tetratricopeptide repeat domain 30A
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VAMP5 vesicle-associated membrane protein 5
WDTC1 WD and tetratricopeptide repeats 1
XDH xanthine dehydrogenase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZFAND5 zinc finger, AN1-type domain 5
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AGO3 argonaute RISC catalytic component 3
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATAD2B ATPase family, AAA domain containing 2B
ATP7B ATPase, Cu++ transporting, beta polypeptide
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
C10ORF88 chromosome 10 open reading frame 88
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CBR4 carbonyl reductase 4
CCDC9 coiled-coil domain containing 9
CHMP6 charged multivesicular body protein 6
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYBG3 beta-gamma crystallin domain containing 3
CUEDC1 CUE domain containing 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DENND4A DENN/MADD domain containing 4A
DSCAM Down syndrome cell adhesion molecule
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXD3 exonuclease 3'-5' domain containing 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP14 FK506 binding protein 14, 22 kDa
FPGT fucose-1-phosphate guanylyltransferase
GLS2 glutaminase 2 (liver, mitochondrial)
GOLGA8B golgin A8 family, member B
GPATCH3 G patch domain containing 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BO histone cluster 1, H2bo
HOXC11 homeobox C11
IFNA14 interferon, alpha 14
IL17RA interleukin 17 receptor A
IREB2 iron-responsive element binding protein 2
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KPNA4 karyopherin alpha 4 (importin alpha 3)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHX6 LIM homeobox 6
LMCD1 LIM and cysteine-rich domains 1
LNPEP leucyl/cystinyl aminopeptidase
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
MANBA mannosidase, beta A, lysosomal
MFSD12 major facilitator superfamily domain containing 12
MYO1E myosin IE
MYO9A myosin IXA
NDE1 nudE neurodevelopment protein 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUBPL nucleotide binding protein-like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP16 poly (ADP-ribose) polymerase family, member 16
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PROCR protein C receptor, endothelial
PYCRL pyrroline-5-carboxylate reductase-like
RNF170 ring finger protein 170
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A4 S100 calcium binding protein A4
SCAI suppressor of cancer cell invasion
SCHIP1 schwannomin interacting protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETD1B SET domain containing 1B
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2D4A SH2 domain containing 4A
SHPK sedoheptulokinase
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STBD1 starch binding domain 1
STX5 syntaxin 5
SUSD4 sushi domain containing 4
TMC5 transmembrane channel-like 5
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TRIM5 tripartite motif containing 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WASF2 WAS protein family, member 2
WDR60 WD repeat domain 60
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF211 zinc finger protein 211
ZNF219 zinc finger protein 219
ZNF778 zinc finger protein 778