cefmetazole-6086 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefmetazole-6086 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACTA1 actin, alpha 1, skeletal muscle
ADAMDEC1 ADAM-like, decysin 1
ADORA1 adenosine A1 receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALOX12B arachidonate 12-lipoxygenase, 12R type
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C10ORF10 chromosome 10 open reading frame 10
C15ORF39 chromosome 15 open reading frame 39
C19ORF73 chromosome 19 open reading frame 73
C7ORF69 chromosome 7 open reading frame 69
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CD2 CD2 molecule
CD34 CD34 molecule
CDRT1 CMT1A duplicated region transcript 1
CEMP1 cementum protein 1
CERS4 ceramide synthase 4
CLCN6 chloride channel, voltage-sensitive 6
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CSF1 colony stimulating factor 1 (macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGKQ diacylglycerol kinase, theta 110kDa
DPYSL4 dihydropyrimidinase-like 4
DSC3 desmocollin 3
DSCR4 Down syndrome critical region 4
DUSP1 dual specificity phosphatase 1
DVL3 dishevelled segment polarity protein 3
ECM1 extracellular matrix protein 1
ELOVL5 ELOVL fatty acid elongase 5
EMCN endomucin
FBXO2 F-box protein 2
FGFBP1 fibroblast growth factor binding protein 1
FXYD2 FXYD domain containing ion transport regulator 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GM2A GM2 ganglioside activator
GPR39 G protein-coupled receptor 39
GRAP GRB2-related adaptor protein
GSK3A glycogen synthase kinase 3 alpha
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2BL histone cluster 1, H2bl
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HOXA10 homeobox A10
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
JPH3 junctophilin 3
KIAA0125 KIAA0125
KIAA1654 KIAA1654 protein
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KLF12 Kruppel-like factor 12
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC3 laminin, gamma 3
LDB3 LIM domain binding 3
LEF1 lymphoid enhancer-binding factor 1
LRRC23 leucine rich repeat containing 23
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MFSD6 major facilitator superfamily domain containing 6
MTRF1L mitochondrial translational release factor 1-like
MUC3B mucin 3B, cell surface associated
MXRA5 matrix-remodelling associated 5
NF1 neurofibromin 1
NOP16 NOP16 nucleolar protein
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX5 paired box 5
PCDHB6 protocadherin beta 6
PEX14 peroxisomal biogenesis factor 14
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RNF122 ring finger protein 122
RPH3A rabphilin 3A
RPL35A ribosomal protein L35a
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
S100A8 S100 calcium binding protein A8
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC39A9 solute carrier family 39, member 9
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYT5 synaptotagmin V
TCF12 transcription factor 12
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TDRD12 tudor domain containing 12
TGM2 transglutaminase 2
TMPRSS15 transmembrane protease, serine 15
TTC38 tetratricopeptide repeat domain 38
TUBA4B tubulin, alpha 4b
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VIPR1 vasoactive intestinal peptide receptor 1
WASL Wiskott-Aldrich syndrome-like
WNT6 wingless-type MMTV integration site family, member 6
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BMP10 bone morphogenetic protein 10
C3ORF18 chromosome 3 open reading frame 18
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD82 CD82 molecule
CEP170B centrosomal protein 170B
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIDEB cell death-inducing DFFA-like effector b
CLCF1 cardiotrophin-like cytokine factor 1
CSF1R colony stimulating factor 1 receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDAR ectodysplasin A receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGL1 fibrinogen-like 1
FILIP1L filamin A interacting protein 1-like
FMOD fibromodulin
FOSL1 FOS-like antigen 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLS2 glutaminase 2 (liver, mitochondrial)
GRAMD1C GRAM domain containing 1C
HDAC11 histone deacetylase 11
HDAC5 histone deacetylase 5
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST2H2AA3 histone cluster 2, H2aa3
HOXC10 homeobox C10
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
INPP1 inositol polyphosphate-1-phosphatase
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A3 leucine rich repeat containing 37, member A3
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEF1 melanoma antigen family F1
MEFV Mediterranean fever
MSI1 musashi RNA-binding protein 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
OLFML2A olfactomedin-like 2A
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRPH peripherin
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVRL3 poliovirus receptor-related 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REPS2 RALBP1 associated Eps domain containing 2
RFXAP regulatory factor X-associated protein
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLPI secretory leukocyte peptidase inhibitor
SNUPN snurportin 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TFF2 trefoil factor 2
TMCC2 transmembrane and coiled-coil domain family 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMLHE trimethyllysine hydroxylase, epsilon
TRAIP TRAF interacting protein
UNC119 unc-119 homolog (C. elegans)
VEGFB vascular endothelial growth factor B
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMAT5 zinc finger, matrin-type 5
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF606 zinc finger protein 606