cefixime-3247 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the cefixime-3247 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ALPK1 alpha-kinase 1
AMH anti-Mullerian hormone
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP33 Rho GTPase activating protein 33
ATG12 autophagy related 12
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP8B bone morphogenetic protein 8b
CA12 carbonic anhydrase XII
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCNJL cyclin J-like
CCNT2 cyclin T2
CD53 CD53 molecule
CDC25A cell division cycle 25A
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRYGC crystallin, gamma C
CTAGE5 CTAGE family, member 5
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL9 cullin 9
DFNB31 deafness, autosomal recessive 31
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOPEY1 dopey family member 1
DSPP dentin sialophosphoprotein
DTNA dystrobrevin, alpha
FAM204A family with sequence similarity 204, member A
FGFR4 fibroblast growth factor receptor 4
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT4 fms-related tyrosine kinase 4
FYB FYN binding protein
GLG1 golgi glycoprotein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H1FX H1 histone family, member X
HIST1H1D histone cluster 1, H1d
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA4 homeobox A4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS2 insulin receptor substrate 2
ITSN1 intersectin 1 (SH3 domain protein)
KAT6A K(lysine) acetyltransferase 6A
KDM6B lysine (K)-specific demethylase 6B
KIF21B kinesin family member 21B
KLF6 Kruppel-like factor 6
LPPR2 lipid phosphate phosphatase-related protein type 2
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MTA1 metastasis associated 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG1 N-myc downstream regulated 1
NRF1 nuclear respiratory factor 1
PAIP2B poly(A) binding protein interacting protein 2B
PCNXL2 pecanex-like 2 (Drosophila)
PCSK7 proprotein convertase subtilisin/kexin type 7
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLDB1 pleckstrin homology-like domain, family B, member 1
PNPLA6 patatin-like phospholipase domain containing 6
PODXL podocalyxin-like
PRB1 proline-rich protein BstNI subfamily 1
PRODH proline dehydrogenase (oxidase) 1
PROSER1 proline and serine rich 1
PTGDR2 prostaglandin D2 receptor 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASAL2 RAS protein activator like 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REM1 RAS (RAD and GEM)-like GTP-binding 1
SDC2 syndecan 2
SF3A1 splicing factor 3a, subunit 1, 120kDa
SIN3B SIN3 transcription regulator family member B
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMC4 structural maintenance of chromosomes 4
SMIM14 small integral membrane protein 14
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST5 suppression of tumorigenicity 5
STX1A syntaxin 1A (brain)
TBCD tubulin folding cofactor D
THRAP3 thyroid hormone receptor associated protein 3
TMEM19 transmembrane protein 19
TOP3A topoisomerase (DNA) III alpha
TP53I11 tumor protein p53 inducible protein 11
TRD T cell receptor delta locus
TRIM36 tripartite motif containing 36
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VIPR2 vasoactive intestinal peptide receptor 2
VPS9D1 VPS9 domain containing 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF318 zinc finger protein 318
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BFSP1 beaded filament structural protein 1, filensin
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
C9ORF9 chromosome 9 open reading frame 9
CAMKMT calmodulin-lysine N-methyltransferase
CHML choroideremia-like (Rab escort protein 2)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXORF56 chromosome X open reading frame 56
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FAM188A family with sequence similarity 188, member A
GADD45G growth arrest and DNA-damage-inducible, gamma
GBP2 guanylate binding protein 2, interferon-inducible
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRB7 growth factor receptor-bound protein 7
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR1 interferon (alpha, beta and omega) receptor 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JUNB jun B proto-oncogene
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MVD mevalonate (diphospho) decarboxylase
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
OVOL1 ovo-like zinc finger 1
PCDHB13 protocadherin beta 13
PDIA3 protein disulfide isomerase family A, member 3
PLA2G10 phospholipase A2, group X
PP14571 uncharacterized LOC100130449
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SECTM1 secreted and transmembrane 1
SIX1 SIX homeobox 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPAG7 sperm associated antigen 7
SRPX sushi-repeat containing protein, X-linked
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
TARP TCR gamma alternate reading frame protein
TCHH trichohyalin
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOM1 target of myb1 (chicken)
TRIM25 tripartite motif containing 25
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
WLS wntless Wnt ligand secretion mediator
YEATS4 YEATS domain containing 4
ZBTB44 zinc finger and BTB domain containing 44
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF85 zinc finger protein 85