cefazolin-7385 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefazolin-7385 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADCY6 adenylate cyclase 6
ADPRH ADP-ribosylarginine hydrolase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL15 ADP-ribosylation factor-like 15
ARMCX4 armadillo repeat containing, X-linked 4
C4BPA complement component 4 binding protein, alpha
C9ORF9 chromosome 9 open reading frame 9
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC170 coiled-coil domain containing 170
CD6 CD6 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLUL1 clusterin-like 1 (retinal)
CNTNAP3B contactin associated protein-like 3B
COL4A6 collagen, type IV, alpha 6
CPN2 carboxypeptidase N, polypeptide 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF11 DDB1 and CUL4 associated factor 11
DFNB31 deafness, autosomal recessive 31
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAL4 dynein, axonemal, light chain 4
DOHH deoxyhypusine hydroxylase/monooxygenase
ESR1 estrogen receptor 1
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FABP7 fatty acid binding protein 7, brain
FASTKD2 FAST kinase domains 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAS7 growth arrest-specific 7
GATA2 GATA binding protein 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLP1R glucagon-like peptide 1 receptor
GMPR guanosine monophosphate reductase
GRK5 G protein-coupled receptor kinase 5
GRM8 glutamate receptor, metabotropic 8
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUK1 guanylate kinase 1
HIST1H2BN histone cluster 1, H2bn
HIST1H4D histone cluster 1, H4d
HOXC4 homeobox C4
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL32 interleukin 32
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCTD14 potassium channel tetramerization domain containing 14
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
MAPK12 mitogen-activated protein kinase 12
MAPK4 mitogen-activated protein kinase 4
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MR1 major histocompatibility complex, class I-related
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO15A myosin XVA
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NF2 neurofibromin 2 (merlin)
NLGN1 neuroligin 1
NPEPL1 aminopeptidase-like 1
NPM3 nucleophosmin/nucleoplasmin 3
OASL 2'-5'-oligoadenylate synthetase-like
PAX2 paired box 2
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
POMT2 protein-O-mannosyltransferase 2
PRB4 proline-rich protein BstNI subfamily 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB6B RAB6B, member RAS oncogene family
RB1 retinoblastoma 1
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
SAPCD1 suppressor APC domain containing 1
SCD5 stearoyl-CoA desaturase 5
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BP2 SH3-domain binding protein 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAB2 stabilin 2
TCP10L t-complex 10-like
TRA2A transformer 2 alpha homolog (Drosophila)
TRAPPC13 trafficking protein particle complex 13
VCAN versican
VCX2 variable charge, X-linked 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WSB1 WD repeat and SOCS box containing 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP17 Rho GTPase activating protein 17
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATP7B ATPase, Cu++ transporting, beta polypeptide
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL9 B-cell CLL/lymphoma 9
BEX4 brain expressed, X-linked 4
C9ORF114 chromosome 9 open reading frame 114
CASKIN2 CASK interacting protein 2
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CEP112 centrosomal protein 112kDa
CFAP44 cilia and flagella associated protein 44
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DENND4C DENN/MADD domain containing 4C
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
ELP3 elongator acetyltransferase complex subunit 3
EPN3 epsin 3
EXOC3 exocyst complex component 3
F3 coagulation factor III (thromboplastin, tissue factor)
GALK1 galactokinase 1
GDAP1 ganglioside induced differentiation associated protein 1
GPATCH3 G patch domain containing 3
GRAMD4 GRAM domain containing 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC4 histone deacetylase 4
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSPA4L heat shock 70kDa protein 4-like
KIAA1551 KIAA1551
KLF2 Kruppel-like factor 2
LHFPL2 lipoma HMGIC fusion partner-like 2
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MCTP1 multiple C2 domains, transmembrane 1
MON1B MON1 secretory trafficking family member B
MTERF4 mitochondrial transcription termination factor 4
MYL5 myosin, light chain 5, regulatory
NABP2 nucleic acid binding protein 2
NADSYN1 NAD synthetase 1
NOL12 nucleolar protein 12
NT5M 5',3'-nucleotidase, mitochondrial
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBL1 retinoblastoma-like 1
RCAN3 RCAN family member 3
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RIN1 Ras and Rab interactor 1
RIPPLY3 ripply transcriptional repressor 3
SCEL sciellin
SECISBP2 SECIS binding protein 2
SESN1 sestrin 1
SFT2D2 SFT2 domain containing 2
SLC22A18 solute carrier family 22, member 18
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG20 small nucleolar RNA host gene 20
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAC SH3 and cysteine rich domain
TAGLN transgelin
THOP1 thimet oligopeptidase 1
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TTC28 tetratricopeptide repeat domain 28
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6NL USP6 N-terminal like
VASP vasodilator-stimulated phosphoprotein
WDR91 WD repeat domain 91
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBED8 zinc finger, BED-type containing 8
ZNF329 zinc finger protein 329
ZNF408 zinc finger protein 408
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene
ZNHIT2 zinc finger, HIT-type containing 2