cefamandole-7394 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefamandole-7394 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALPPL2 alkaline phosphatase, placental-like 2
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP28 Rho GTPase activating protein 28
ARHGAP35 Rho GTPase activating protein 35
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP1 bone morphogenetic protein 1
CACYBP calcyclin binding protein
CADM4 cell adhesion molecule 4
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP1 caspase 1, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CES2 carboxylesterase 2
CLDN11 claudin 11
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIO3 deiodinase, iodothyronine, type III
DOHH deoxyhypusine hydroxylase/monooxygenase
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
DZIP1 DAZ interacting zinc finger protein 1
EFNA3 ephrin-A3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
EWSR1 EWS RNA-binding protein 1
FBRS fibrosin
FBXL15 F-box and leucine-rich repeat protein 15
FGF5 fibroblast growth factor 5
FRMPD1 FERM and PDZ domain containing 1
FYB FYN binding protein
GPR135 G protein-coupled receptor 135
GPR137 G protein-coupled receptor 137
GREB1L growth regulation by estrogen in breast cancer-like
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H3I histone cluster 1, H3i
HOXC4 homeobox C4
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
IL17RA interleukin 17 receptor A
IL1RL1 interleukin 1 receptor-like 1
IL32 interleukin 32
IQSEC2 IQ motif and Sec7 domain 2
KIFC3 kinesin family member C3
KRT17 keratin 17, type I
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN7B lin-7 homolog B (C. elegans)
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MT1M metallothionein 1M
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PANK3 pantothenate kinase 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDS5A PDS5 cohesin associated factor A
PLCG1 phospholipase C, gamma 1
PLXNA3 plexin A3
POMT2 protein-O-mannosyltransferase 2
PVT1 Pvt1 oncogene (non-protein coding)
RAD52 RAD52 homolog (S. cerevisiae)
RAP1GAP RAP1 GTPase activating protein
RBM34 RNA binding motif protein 34
RBM48 RNA binding motif protein 48
RBMS2 RNA binding motif, single stranded interacting protein 2
RECQL5 RecQ protein-like 5
RHOT2 ras homolog family member T2
RPS3A ribosomal protein S3A
S1PR1 sphingosine-1-phosphate receptor 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH2D2A SH2 domain containing 2A
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMC1A structural maintenance of chromosomes 1A
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TNK1 tyrosine kinase, non-receptor, 1
TRAPPC13 trafficking protein particle complex 13
TSPAN8 tetraspanin 8
TTC12 tetratricopeptide repeat domain 12
TUBA3C tubulin, alpha 3c
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR78 WD repeat domain 78
WT1 Wilms tumor 1
ZNF222 zinc finger protein 222
ZNF592 zinc finger protein 592
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ACVR2B activin A receptor, type IIB
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASCC3 activating signal cointegrator 1 complex subunit 3
BAG4 BCL2-associated athanogene 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAPN15 calpain 15
CBX7 chromobox homolog 7
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CHM choroideremia (Rab escort protein 1)
CLEC10A C-type lectin domain family 10, member A
CLEC2B C-type lectin domain family 2, member B
CPED1 cadherin-like and PC-esterase domain containing 1
CTSK cathepsin K
DIXDC1 DIX domain containing 1
DNMBP dynamin binding protein
EAF2 ELL associated factor 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC3 exocyst complex component 3
FZD3 frizzled class receptor 3
GALK1 galactokinase 1
GLDC glycine dehydrogenase (decarboxylating)
GOLGA1 golgin A1
GRWD1 glutamate-rich WD repeat containing 1
GTF2I general transcription factor IIi
HINFP histone H4 transcription factor
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
IREB2 iron-responsive element binding protein 2
ITPKC inositol-trisphosphate 3-kinase C
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0513 KIAA0513
KRT15 keratin 15, type I
LMBR1L limb development membrane protein 1-like
LMO7 LIM domain 7
MAGEA6 melanoma antigen family A6
MANBA mannosidase, beta A, lysosomal
MAP9 microtubule-associated protein 9
MCM9 minichromosome maintenance complex component 9
MED22 mediator complex subunit 22
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MOB3B MOB kinase activator 3B
MRPL44 mitochondrial ribosomal protein L44
MVP major vault protein
MYL5 myosin, light chain 5, regulatory
NBEA neurobeachin
NCS1 neuronal calcium sensor 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NINJ1 ninjurin 1
NINL ninein-like
NPDC1 neural proliferation, differentiation and control, 1
NT5M 5',3'-nucleotidase, mitochondrial
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTK6 protein tyrosine kinase 6
RBM47 RNA binding motif protein 47
RNF2 ring finger protein 2
S100A3 S100 calcium binding protein A3
SCAI suppressor of cancer cell invasion
SCG5 secretogranin V
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETBP1 SET binding protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNX15 sorting nexin 15
SPAG4 sperm associated antigen 4
STIM1 stromal interaction molecule 1
TMC7 transmembrane channel-like 7
TMEM212 transmembrane protein 212
TPRA1 transmembrane protein, adipocyte asscociated 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB14 zinc finger and BTB domain containing 14
ZDHHC11 zinc finger, DHHC-type containing 11
ZMAT5 zinc finger, matrin-type 5
ZNF253 zinc finger protein 253
ZNF273 zinc finger protein 273
ZNF408 zinc finger protein 408
ZNF468 zinc finger protein 468
ZNF510 zinc finger protein 510
ZNF671 zinc finger protein 671