cefamandole-4718 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the cefamandole-4718 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADGRG2 adhesion G protein-coupled receptor G2
ADRBK1 adrenergic, beta, receptor kinase 1
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
ARTN artemin
ASIC1 acid sensing (proton gated) ion channel 1
ATM ATM serine/threonine kinase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BMP5 bone morphogenetic protein 5
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD47 CD47 molecule
CDC14A cell division cycle 14A
CDK18 cyclin-dependent kinase 18
COL5A1 collagen, type V, alpha 1
CRMP1 collapsin response mediator protein 1
CSF1 colony stimulating factor 1 (macrophage)
CTBP2 C-terminal binding protein 2
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR4 chemokine (C-X-C motif) receptor 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCN decorin
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DTX3 deltex 3, E3 ubiquitin ligase
DUSP4 dual specificity phosphatase 4
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EVA1B eva-1 homolog B (C. elegans)
FH fumarate hydratase
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GID4 GID complex subunit 4
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GREB1 growth regulation by estrogen in breast cancer 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HFE hemochromatosis
HOXB2 homeobox B2
IL5RA interleukin 5 receptor, alpha
IL6ST interleukin 6 signal transducer
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIAA0125 KIAA0125
KITLG KIT ligand
LAT2 linker for activation of T cells family, member 2
LCMT2 leucine carboxyl methyltransferase 2
LIMCH1 LIM and calponin homology domains 1
LOC157562 uncharacterized LOC157562
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEF2D myocyte enhancer factor 2D
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MR1 major histocompatibility complex, class I-related
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCALD neurocalcin delta
NDRG2 NDRG family member 2
NUP54 nucleoporin 54kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OGDHL oxoglutarate dehydrogenase-like
PARD6B par-6 family cell polarity regulator beta
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHA6 protocadherin alpha 6
PCDHGB5 protocadherin gamma subfamily B, 5
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSME4 proteasome (prosome, macropain) activator subunit 4
PTHLH parathyroid hormone-like hormone
QKI QKI, KH domain containing, RNA binding
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASAL2 RAS protein activator like 2
RFXAP regulatory factor X-associated protein
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS2 ribosomal protein S2
RRAGB Ras-related GTP binding B
RS1 retinoschisin 1
RUNX1 runt-related transcription factor 1
SCAF4 SR-related CTD-associated factor 4
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SLC43A3 solute carrier family 43, member 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRN3 striatin, calmodulin binding protein 3
TAPBP TAP binding protein (tapasin)
TBL2 transducin (beta)-like 2
TESC tescalcin
TGFB2 transforming growth factor, beta 2
TMEM63A transmembrane protein 63A
TRD T cell receptor delta locus
VEZT vezatin, adherens junctions transmembrane protein
ZNF24 zinc finger protein 24
ZNF304 zinc finger protein 304
ZNF34 zinc finger protein 34
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF750 zinc finger protein 750
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABI3BP ABI family, member 3 (NESH) binding protein
ABLIM3 actin binding LIM protein family, member 3
AFF4 AF4/FMR2 family, member 4
BAG4 BCL2-associated athanogene 4
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CHML choroideremia-like (Rab escort protein 2)
CLCN2 chloride channel, voltage-sensitive 2
CLSPN claspin
COL4A5 collagen, type IV, alpha 5
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CTIF CBP80/20-dependent translation initiation factor
CXADR coxsackie virus and adenovirus receptor
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
ELSPBP1 epididymal sperm binding protein 1
ETAA1 Ewing tumor-associated antigen 1
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
FLJ21369 uncharacterized protein FLJ21369
FLRT3 fibronectin leucine rich transmembrane protein 3
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
HCFC2 host cell factor C2
HIST1H2BN histone cluster 1, H2bn
HIST1H3B histone cluster 1, H3b
HIST1H3I histone cluster 1, H3i
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPB6 heat shock protein, alpha-crystallin-related, B6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT31 keratin 31, type I
LMBR1L limb development membrane protein 1-like
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAP1S microtubule-associated protein 1S
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFAP2 microfibrillar-associated protein 2
MUC3B mucin 3B, cell surface associated
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
NPR3 natriuretic peptide receptor 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PEX26 peroxisomal biogenesis factor 26
PLAT plasminogen activator, tissue
PMEL premelanosome protein
PRB3 proline-rich protein BstNI subfamily 3
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS53 protease, serine, 53
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPAP1 RNA polymerase II associated protein 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SMA4 glucuronidase, beta pseudogene
SNTA1 syntrophin, alpha 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SREK1IP1 SREK1-interacting protein 1
STARD5 StAR-related lipid transfer (START) domain containing 5
STIM1 stromal interaction molecule 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD12 tudor domain containing 12
TLN1 talin 1
UBQLN4 ubiquilin 4
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB44 zinc finger and BTB domain containing 44
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF219 zinc finger protein 219
ZNF816 zinc finger protein 816