cefalotin-6819 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefalotin-6819 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADGRG1 adhesion G protein-coupled receptor G1
ALOX15 arachidonate 15-lipoxygenase
AMPD3 adenosine monophosphate deaminase 3
ANGPTL2 angiopoietin-like 2
AQP4 aquaporin 4
ARHGAP26 Rho GTPase activating protein 26
ATP9A ATPase, class II, type 9A
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CA4 carbonic anhydrase IV
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CNPY4 canopy FGF signaling regulator 4
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DES desmin
DTNB dystrobrevin, beta
EBI3 Epstein-Barr virus induced 3
EHBP1L1 EH domain binding protein 1-like 1
EMCN endomucin
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
FBXO21 F-box protein 21
FLOT1 flotillin 1
FOXO4 forkhead box O4
GIMAP5 GTPase, IMAP family member 5
GNRHR gonadotropin-releasing hormone receptor
GPR137 G protein-coupled receptor 137
GRM2 glutamate receptor, metabotropic 2
GRM8 glutamate receptor, metabotropic 8
GSTP1 glutathione S-transferase pi 1
HIPK3 homeodomain interacting protein kinase 3
KAT6A K(lysine) acetyltransferase 6A
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KDM5A lysine (K)-specific demethylase 5A
KEL Kell blood group, metallo-endopeptidase
KIAA0754 KIAA0754
KIFC3 kinesin family member C3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLF13 Kruppel-like factor 13
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
LIN7A lin-7 homolog A (C. elegans)
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPL lipoprotein lipase
LY86 lymphocyte antigen 86
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
MLANA melan-A
MLNR motilin receptor
MMP11 matrix metallopeptidase 11
MUC3B mucin 3B, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO7A myosin VIIA
ONECUT2 one cut homeobox 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAPPA2 pappalysin 2
PCDH12 protocadherin 12
PCDH17 protocadherin 17
PER2 period circadian clock 2
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PML promyelocytic leukemia
PRKCE protein kinase C, epsilon
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RARG retinoic acid receptor, gamma
RGS12 regulator of G-protein signaling 12
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
SCAPER S-phase cyclin A-associated protein in the ER
SDS serine dehydratase
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SPEF1 sperm flagellar 1
SSTR5 somatostatin receptor 5
SULT4A1 sulfotransferase family 4A, member 1
TAS2R10 taste receptor, type 2, member 10
TCP11L1 t-complex 11, testis-specific-like 1
TGM2 transglutaminase 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53I11 tumor protein p53 inducible protein 11
TPM3 tropomyosin 3
TRAPPC9 trafficking protein particle complex 9
TTC38 tetratricopeptide repeat domain 38
TTC9 tetratricopeptide repeat domain 9
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA4B tubulin, alpha 4b
WDFY3 WD repeat and FYVE domain containing 3
WNT10B wingless-type MMTV integration site family, member 10B
XYLB xylulokinase homolog (H. influenzae)
ZFPL1 zinc finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF460 zinc finger protein 460
ZP2 zona pellucida glycoprotein 2 (sperm receptor)

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACOT8 acyl-CoA thioesterase 8
ADCY6 adenylate cyclase 6
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
C12ORF4 chromosome 12 open reading frame 4
C19ORF73 chromosome 19 open reading frame 73
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CHKB choline kinase beta
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRIP1 cysteine-rich protein 1 (intestinal)
CST6 cystatin E/M
CTC1 CTS telomere maintenance complex component 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEAF1 DEAF1 transcription factor
DYSF dysferlin
EIF5A2 eukaryotic translation initiation factor 5A2
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM204A family with sequence similarity 204, member A
FAM46C family with sequence similarity 46, member C
FBXO31 F-box protein 31
FER fer (fps/fes related) tyrosine kinase
FGGY FGGY carbohydrate kinase domain containing
FOXI1 forkhead box I1
GAMT guanidinoacetate N-methyltransferase
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HMOX1 heme oxygenase 1
HOXC8 homeobox C8
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGSF1 immunoglobulin superfamily, member 1
JMJD4 jumonji domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
KRT16 keratin 16, type I
LHX6 LIM homeobox 6
LMBR1L limb development membrane protein 1-like
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NDRG4 NDRG family member 4
NES nestin
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPY5R neuropeptide Y receptor Y5
OGFRL1 opioid growth factor receptor-like 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PADI3 peptidyl arginine deiminase, type III
PHC2 polyhomeotic homolog 2 (Drosophila)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G3 phospholipase A2, group III
PLXNA3 plexin A3
PNPLA6 patatin-like phospholipase domain containing 6
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
QTRT1 queuine tRNA-ribosyltransferase 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RECQL4 RecQ protein-like 4
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC38A10 solute carrier family 38, member 10
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
TBC1D19 TBC1 domain family, member 19
THBS3 thrombospondin 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TMEM51 transmembrane protein 51
TPST2 tyrosylprotein sulfotransferase 2
TTC33 tetratricopeptide repeat domain 33
USP36 ubiquitin specific peptidase 36
VGF VGF nerve growth factor inducible
WDR46 WD repeat domain 46
WDR76 WD repeat domain 76
ZFP69B ZFP69 zinc finger protein B
ZNF282 zinc finger protein 282
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNRD1-AS1 ZNRD1 antisense RNA 1