cefalotin-4482 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cefalotin-4482 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
ADCY9 adenylate cyclase 9
AIM1L absent in melanoma 1-like
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD3 adenosine monophosphate deaminase 3
ANP32A-IT1 ANP32A intronic transcript 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ASF1A anti-silencing function 1A histone chaperone
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP2 bone morphogenetic protein 2
C17ORF53 chromosome 17 open reading frame 53
C3 complement component 3
CACFD1 calcium channel flower domain containing 1
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CFLAR CASP8 and FADD-like apoptosis regulator
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIDEB cell death-inducing DFFA-like effector b
CLTCL1 clathrin, heavy chain-like 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL11A2 collagen, type XI, alpha 2
COL16A1 collagen, type XVI, alpha 1
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CSNK1G1 casein kinase 1, gamma 1
DOCK1 dedicator of cytokinesis 1
DSTYK dual serine/threonine and tyrosine protein kinase
ELSPBP1 epididymal sperm binding protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FAM63A family with sequence similarity 63, member A
FBXO40 F-box protein 40
FGF16 fibroblast growth factor 16
GPR85 G protein-coupled receptor 85
HAL histidine ammonia-lyase
HOMER3 homer scaffolding protein 3
HOXD1 homeobox D1
ICOSLG inducible T-cell co-stimulator ligand
IGHD immunoglobulin heavy constant delta
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD14 potassium channel tetramerization domain containing 14
KIAA1467 KIAA1467
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LAMC3 laminin, gamma 3
LIMD1 LIM domains containing 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
NCAPH2 non-SMC condensin II complex, subunit H2
NCOR2 nuclear receptor corepressor 2
NPHP1 nephronophthisis 1 (juvenile)
NRP2 neuropilin 2
PCDHB3 protocadherin beta 3
PDCD2 programmed cell death 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLK3 polo-like kinase 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKCE protein kinase C, epsilon
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
QPCTL glutaminyl-peptide cyclotransferase-like
RAB6A RAB6A, member RAS oncogene family
RLN1 relaxin 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
SAFB2 scaffold attachment factor B2
SBNO1 strawberry notch homolog 1 (Drosophila)
SFTPB surfactant protein B
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SORT1 sortilin 1
SPHK2 sphingosine kinase 2
STOML1 stomatin (EPB72)-like 1
TBX6 T-box 6
TCP11 t-complex 11, testis-specific
TCP11L1 t-complex 11, testis-specific-like 1
TFCP2L1 transcription factor CP2-like 1
TGFB2 transforming growth factor, beta 2
TLN2 talin 2
TLR2 toll-like receptor 2
TMPRSS15 transmembrane protease, serine 15
TMPRSS6 transmembrane protease, serine 6
TNS1 tensin 1
TRIM29 tripartite motif containing 29
TTC12 tetratricopeptide repeat domain 12
VAV1 vav 1 guanine nucleotide exchange factor
VCX2 variable charge, X-linked 2
VWA5A von Willebrand factor A domain containing 5A
WSB1 WD repeat and SOCS box containing 1
ZBTB33 zinc finger and BTB domain containing 33
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF778 zinc finger protein 778
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACADSB acyl-CoA dehydrogenase, short/branched chain
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATAD5 ATPase family, AAA domain containing 5
ATG10 autophagy related 10
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHD1 bromo adjacent homology domain containing 1
C14ORF93 chromosome 14 open reading frame 93
CCL27 chemokine (C-C motif) ligand 27
CCNJL cyclin J-like
CD3EAP CD3e molecule, epsilon associated protein
CD70 CD70 molecule
CHMP1A charged multivesicular body protein 1A
CLDN11 claudin 11
CNTLN centlein, centrosomal protein
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGKE diacylglycerol kinase, epsilon 64kDa
DUS2 dihydrouridine synthase 2
EGF epidermal growth factor
EIF5A2 eukaryotic translation initiation factor 5A2
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FOXN2 forkhead box N2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR19 G protein-coupled receptor 19
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H2BJ histone cluster 1, H2bj
HIST1H3A histone cluster 1, H3a
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA7 homeobox A7
HOXC8 homeobox C8
HPN hepsin
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL12A interleukin 12A
IL17RB interleukin 17 receptor B
IL33 interleukin 33
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIAA1107 KIAA1107
KIRREL kin of IRRE like (Drosophila)
LIMD2 LIM domain containing 2
LPPR4 lipid phosphate phosphatase-related protein type 4
LY86 lymphocyte antigen 86
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
NKX3-2 NK3 homeobox 2
NMB neuromedin B
NME5 NME/NM23 family member 5
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPIPB15 nuclear pore complex interacting protein family, member B15
PAIP2B poly(A) binding protein interacting protein 2B
PARP6 poly (ADP-ribose) polymerase family, member 6
PDGFA platelet-derived growth factor alpha polypeptide
PID1 phosphotyrosine interaction domain containing 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLL polymerase (DNA directed), lambda
POU3F2 POU class 3 homeobox 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
RPS14P3 ribosomal protein S14 pseudogene 3
SEPP1 selenoprotein P, plasma, 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SLC22A14 solute carrier family 22, member 14
SLN sarcolipin
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPATA2L spermatogenesis associated 2-like
STAP2 signal transducing adaptor family member 2
STARD5 StAR-related lipid transfer (START) domain containing 5
SYNGR3 synaptogyrin 3
TCTN2 tectonic family member 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMEM180 transmembrane protein 180
TNNI3 troponin I type 3 (cardiac)
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VN1R1 vomeronasal 1 receptor 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF350 zinc finger protein 350
ZNF442 zinc finger protein 442
ZNF552 zinc finger protein 552
ZNF667 zinc finger protein 667