cefadroxil-4161 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the cefadroxil-4161 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AIM2 absent in melanoma 2
ALOX15B arachidonate 15-lipoxygenase, type B
AMACR alpha-methylacyl-CoA racemase
ANK1 ankyrin 1, erythrocytic
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARHGAP24 Rho GTPase activating protein 24
BHMT2 betaine--homocysteine S-methyltransferase 2
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF16 chromosome 11 open reading frame 16
C1RL complement component 1, r subcomponent-like
C8ORF44 chromosome 8 open reading frame 44
CCDC70 coiled-coil domain containing 70
CCR4 chemokine (C-C motif) receptor 4
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD1E CD1e molecule
CDC14B cell division cycle 14B
CDO1 cysteine dioxygenase type 1
CFDP1 craniofacial development protein 1
CIB2 calcium and integrin binding family member 2
COL4A1 collagen, type IV, alpha 1
COL5A2 collagen, type V, alpha 2
CRP C-reactive protein, pentraxin-related
CTNNA2 catenin (cadherin-associated protein), alpha 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DTX2 deltex 2, E3 ubiquitin ligase
EDN1 endothelin 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
EVA1B eva-1 homolog B (C. elegans)
FAM110D family with sequence similarity 110, member D
FGF18 fibroblast growth factor 18
FGF6 fibroblast growth factor 6
FYB FYN binding protein
GALR3 galanin receptor 3
GAS2L1 growth arrest-specific 2 like 1
GFER growth factor, augmenter of liver regeneration
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNRH2 gonadotropin-releasing hormone 2
GRIK1 glutamate receptor, ionotropic, kainate 1
GSK3A glycogen synthase kinase 3 alpha
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H2BN histone cluster 1, H2bn
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXB5 homeobox B5
IFNA14 interferon, alpha 14
IL2RB interleukin 2 receptor, beta
IL36G interleukin 36, gamma
ITM2A integral membrane protein 2A
JAM3 junctional adhesion molecule 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYZL6 lysozyme-like 6
MAP2K7 mitogen-activated protein kinase kinase 7
MCAM melanoma cell adhesion molecule
MCTP1 multiple C2 domains, transmembrane 1
MED18 mediator complex subunit 18
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PCDHB6 protocadherin beta 6
PDAP1 PDGFA associated protein 1
PDE4D phosphodiesterase 4D, cAMP-specific
PKNOX2 PBX/knotted 1 homeobox 2
PODNL1 podocan-like 1
POFUT1 protein O-fucosyltransferase 1
PRB1 proline-rich protein BstNI subfamily 1
PROL1 proline rich, lacrimal 1
PROSC proline synthetase co-transcribed homolog (bacterial)
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RABGAP1 RAB GTPase activating protein 1
RHOH ras homolog family member H
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SOGA1 suppressor of glucose, autophagy associated 1
SUSD5 sushi domain containing 5
SYNJ2 synaptojanin 2
TEK TEK tyrosine kinase, endothelial
TMPRSS4 transmembrane protease, serine 4
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRIM10 tripartite motif containing 10
TRIM29 tripartite motif containing 29
TTC9 tetratricopeptide repeat domain 9
TUBA4B tubulin, alpha 4b
VNN2 vanin 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF440 zinc finger protein 440
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTL8 actin-like 8
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARRB1 arrestin, beta 1
ATG10 autophagy related 10
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BHLHE41 basic helix-loop-helix family, member e41
C22ORF29 chromosome 22 open reading frame 29
CAMK1 calcium/calmodulin-dependent protein kinase I
CD8A CD8a molecule
CDK18 cyclin-dependent kinase 18
CES3 carboxylesterase 3
CLEC4E C-type lectin domain family 4, member E
CPB2 carboxypeptidase B2 (plasma)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FAM76A family with sequence similarity 76, member A
FBXO2 F-box protein 2
FSCN3 fascin actin-bundling protein 3, testicular
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GMPR guanosine monophosphate reductase
GPR182 G protein-coupled receptor 182
GPRASP1 G protein-coupled receptor associated sorting protein 1
HCAR3 hydroxycarboxylic acid receptor 3
HDAC5 histone deacetylase 5
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HOXC5 homeobox C5
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ING4 inhibitor of growth family, member 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM8 lysine (K)-specific demethylase 8
KIAA1024 KIAA1024
KIF13A kinesin family member 13A
KREMEN2 kringle containing transmembrane protein 2
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTR1 leucine-zipper-like transcription regulator 1
MAPK10 mitogen-activated protein kinase 10
MAST3 microtubule associated serine/threonine kinase 3
MDM4 MDM4, p53 regulator
MMP3 matrix metallopeptidase 3
MOB3B MOB kinase activator 3B
MYO1F myosin IF
NME5 NME/NM23 family member 5
NT5E 5'-nucleotidase, ecto (CD73)
OCA2 oculocutaneous albinism II
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PARD6A par-6 family cell polarity regulator alpha
PARG poly (ADP-ribose) glycohydrolase
PCDHB13 protocadherin beta 13
PCDHGB5 protocadherin gamma subfamily B, 5
PER3 period circadian clock 3
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POPDC3 popeye domain containing 3
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSG4 pregnancy specific beta-1-glycoprotein 4
PXN paxillin
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RASL11B RAS-like, family 11, member B
RGS19 regulator of G-protein signaling 19
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF208 ring finger protein 208
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPINK5 serine peptidase inhibitor, Kazal type 5
ST5 suppression of tumorigenicity 5
STARD3 StAR-related lipid transfer (START) domain containing 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM121 transmembrane protein 121
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAF2 TNF receptor-associated factor 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM68 tripartite motif containing 68
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTC30A tetratricopeptide repeat domain 30A
UPP1 uridine phosphorylase 1
ZNF444 zinc finger protein 444
ZNF701 zinc finger protein 701