cefadroxil-4080 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the cefadroxil-4080 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AHSG alpha-2-HS-glycoprotein
AIM1L absent in melanoma 1-like
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX12 arachidonate 12-lipoxygenase
APP amyloid beta (A4) precursor protein
ARSA arylsulfatase A
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BGN biglycan
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C16ORF59 chromosome 16 open reading frame 59
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CKM creatine kinase, muscle
CNGB1 cyclic nucleotide gated channel beta 1
COL17A1 collagen, type XVII, alpha 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
ESRRG estrogen-related receptor gamma
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGB fibrinogen beta chain
FGF22 fibroblast growth factor 22
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC3 glypican 3
GPR183 G protein-coupled receptor 183
GSDMB gasdermin B
HAPLN1 hyaluronan and proteoglycan link protein 1
HDAC6 histone deacetylase 6
HGD homogentisate 1,2-dioxygenase
HOPX HOP homeobox
IL32 interleukin 32
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KLHL22 kelch-like family member 22
LGALS14 lectin, galactoside-binding, soluble, 14
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC284244 uncharacterized LOC284244
LRRK1 leucine-rich repeat kinase 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MEG3 maternally expressed 3 (non-protein coding)
MFSD7 major facilitator superfamily domain containing 7
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLANA melan-A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYB v-myb avian myeloblastosis viral oncogene homolog
MYT1L myelin transcription factor 1-like
NOX1 NADPH oxidase 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NUP188 nucleoporin 188kDa
OBSL1 obscurin-like 1
PAX8 paired box 8
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDPN podoplanin
PGLYRP4 peptidoglycan recognition protein 4
PHOX2B paired-like homeobox 2b
POU2F2 POU class 2 homeobox 2
PRKCQ protein kinase C, theta
PRTN3 proteinase 3
RASA3 RAS p21 protein activator 3
RGS4 regulator of G-protein signaling 4
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RIF1 replication timing regulatory factor 1
RPLP2 ribosomal protein, large, P2
SIL1 SIL1 nucleotide exchange factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SUGP1 SURP and G patch domain containing 1
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TMPRSS2 transmembrane protease, serine 2
TP63 tumor protein p63
TRA T cell receptor alpha locus
TREM1 triggering receptor expressed on myeloid cells 1
TRGV5 T cell receptor gamma variable 5
TRIM29 tripartite motif containing 29
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
VIL1 villin 1
VPRBP Vpr (HIV-1) binding protein
WT1-AS WT1 antisense RNA
XCR1 chemokine (C motif) receptor 1
ZBTB20 zinc finger and BTB domain containing 20
ZFP2 ZFP2 zinc finger protein
ZFPL1 zinc finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADTRP androgen-dependent TFPI-regulating protein
AGO4 argonaute RISC catalytic component 4
ALS2CL ALS2 C-terminal like
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASTN1 astrotactin 1
ATAT1 alpha tubulin acetyltransferase 1
BTC betacellulin
BTF3P11 basic transcription factor 3 pseudogene 11
C1R complement component 1, r subcomponent
C5 complement component 5
CA11 carbonic anhydrase XI
CAPN15 calpain 15
CDK6 cyclin-dependent kinase 6
CENPJ centromere protein J
CLDN15 claudin 15
CLEC16A C-type lectin domain family 16, member A
CNTFR ciliary neurotrophic factor receptor
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREB5 cAMP responsive element binding protein 5
DLK2 delta-like 2 homolog (Drosophila)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
ECM1 extracellular matrix protein 1
ELP6 elongator acetyltransferase complex subunit 6
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM118A family with sequence similarity 118, member A
FBXO2 F-box protein 2
FBXO31 F-box protein 31
FURIN furin (paired basic amino acid cleaving enzyme)
GALT galactose-1-phosphate uridylyltransferase
GMIP GEM interacting protein
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H3A histone cluster 1, H3a
HOXA6 homeobox A6
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1549L KIAA1549-like
KIRREL kin of IRRE like (Drosophila)
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LY6G5C lymphocyte antigen 6 complex, locus G5C
MANBA mannosidase, beta A, lysosomal
MED31 mediator complex subunit 31
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP9 matrix metallopeptidase 9
MTSS1L metastasis suppressor 1-like
NBEAL2 neurobeachin-like 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NRSN2 neurensin 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALMD palmdelphin
PCDH12 protocadherin 12
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLBD1 phospholipase B domain containing 1
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRF1 perforin 1 (pore forming protein)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM38 RNA binding motif protein 38
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD2A RWD domain containing 2A
SAYSD1 SAYSVFN motif domain containing 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMR3A submaxillary gland androgen regulated protein 3A
SNORA21 small nucleolar RNA, H/ACA box 21
SNPH syntaphilin
SNRPN small nuclear ribonucleoprotein polypeptide N
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
WDR4 WD repeat domain 4
WDR62 WD repeat domain 62
ZBTB22 zinc finger and BTB domain containing 22
ZNF232 zinc finger protein 232
ZNF749 zinc finger protein 749
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein