cd95 death-inducing signaling complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. (Gene Ontology, GO_0031265)
External Link http://amigo.geneontology.org/amigo/term/GO:0031265
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Genes

6 proteins localized to the cd95 death-inducing signaling complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CFLAR CASP8 and FADD-like apoptosis regulator
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAS Fas cell surface death receptor